FLUVOXAMINE IN THE TREATMENT OF DEPRESSION - A DOUBLE-BLIND COMPARISON WITH IMIPRAMINE AND PLACEBO IN OUTPATIENTS WITH MAJOR DEPRESSION

1992 ◽  
Vol 15 ◽  
pp. 416B ◽  
Author(s):  
L. Fabre ◽  
J. Vettraino ◽  
L. Birkhimer ◽  
V. Houser
1992 ◽  
Vol 26 (3) ◽  
pp. 454-458 ◽  
Author(s):  
Larry Evans ◽  
Tom George ◽  
Brendan O'sullivan ◽  
Philip Mitchell ◽  
Gordon Johnson ◽  
...  

This paper reports the results of a multicentre study of the new monoamine oxidase inhibitor, moclobemide, in the treatment of major depression. Moclobemide is a specific monoamine oxidase-A inhibitor which does not bind irreversibly to the enzyme, unlike the currently available MAOIs. Recent studies would suggest that in subjects taking moclobemide blood pressure elevation caused by tyramine is significantly less than that induced by the irreversible MAOIs, particularly when tyramine is administered in an oral form. Forty-eight patients with major depression were randomly allocated to treatment with either moclobemide or amitriptyline for 4 weeks in a double-blind comparison. There were no statistically significant differences between the two groups on measures of efficacy. Patients taking amitriptyline reported a greater number of side-effects and more patients in the amitriptyline group dropped out because of these. There were no reports of interactions with tyramine-containing foods.


1998 ◽  
Vol 8 ◽  
pp. S207
Author(s):  
S. Eriksson ◽  
K. Behnke ◽  
J. Segaard ◽  
P. Østergaard ◽  
T. Koskinen ◽  
...  

1989 ◽  
Vol 4 (2) ◽  
pp. 127-134 ◽  
Author(s):  
JOHN P. FEIGHNER ◽  
WILLIAM F. BOYER ◽  
CHARLES H. MERIDETH ◽  
G. GORDON HENDRICKSON

2005 ◽  
Vol 66 (06) ◽  
pp. 708-716 ◽  
Author(s):  
Veronica Murray ◽  
Magnus von Arbin ◽  
Aniko Bartfai ◽  
Anna-Lena Berggren ◽  
Anne-Marie Landtblom ◽  
...  

1971 ◽  
Vol 19 (2) ◽  
pp. 153-162 ◽  
Author(s):  
M. S. Lipsedge ◽  
W. Linford Rees ◽  
D. J. Pike

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