A double-blind comparison of the efficacy and safety of paroxetine and imipramine in the treatment of depression with dementia

1996 ◽  
Vol 11 ◽  
pp. 345s ◽  
Author(s):  
B. Hunter ◽  
R. Judge
Keyword(s):  
Efficacy And Safety ◽  
Double Blind ◽  
Treatment Of Depression ◽  
Blind Comparison

Double-Blind Comparison of Maternal Analgesia and Neonatal Neurobehaviour following Intravenous Butorphanol and Meperidine

1979 ◽  
Vol 7 (3) ◽  
pp. 224-230 ◽  
Author(s):  
Robert Hodgkinson ◽  
Robert W Huff ◽  
Robert H Hayashi ◽  
Farkhanda J Husain
Keyword(s):  
Side Effects ◽  
Severe Pain ◽  
Randomized Study ◽  
Analgesic Efficacy ◽  
Foetal Heart Rate ◽  
Efficacy And Safety ◽  
Cervical Dilation ◽  
Double Blind ◽  
Significant Difference ◽  
Blind Comparison

Butorphanol (1 mg and 2 mg) and meperidine (40 mg and 80 mg), given intravenously, were evaluated for analgesic efficacy and safety in a double-blind randomized study employing 200 consenting pre-partum patients in moderate to severe pain during the late first stage of labour. Both drugs provided adequate relief of pain to the mothers. There was no significant difference in the rate of cervical dilation, the foetal heart rate, the Apgar score, pain relief or neonatal neurobehavioural scores between those receiving butorphanol and those receiving meperidine. Twenty-two mothers who received butorphanol and eleven who received meperidine nursed their infants with no adverse effects observed. Side-effects were generally infrequent in this study; however, more side-effects were reported by the patients and observed by the investigator in the meperidine-treated cases (13%) than in the cases treated with butorphanol (2%).

A double-blind comparison of dothiepin and amitriptyline for the treatment of depression with anxiety

1971 ◽  
Vol 19 (2) ◽  
pp. 153-162 ◽  
Author(s):  
M. S. Lipsedge ◽  
W. Linford Rees ◽  
D. J. Pike
Keyword(s):  
Double Blind ◽  
Treatment Of Depression ◽  
Blind Comparison
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