Fluvoxamine augmentation of antipsychotics improves negative symptoms in psychotic chronic schizophrenic patients: a placebo-controlled study

2000 ◽  
Vol 15 (5) ◽  
pp. 257-261 ◽  
Author(s):  
H. Silver ◽  
I. Barash ◽  
N. Aharon ◽  
A. Kaplan ◽  
M. Poyurovsky
Keyword(s):  
Negative Symptoms ◽  
Controlled Study ◽  
Chronic Schizophrenic ◽  
Schizophrenic Patients

Self-Reports in Chronic Schizophrenic Patients with Primary Negative Symptoms: Preliminary Results

1990 ◽  
Vol 23 (04) ◽  
pp. 195-197 ◽  
Author(s):  
H. Gerbaldo ◽  
C. de las Carreras ◽  
A. Osuna ◽  
G. Laves ◽  
J. Orlando
Keyword(s):  
Negative Symptoms ◽  
Chronic Schizophrenic ◽  
Preliminary Results ◽  
Self Reports ◽  
Schizophrenic Patients

A Controlled Study of the Effectiveness of Trifluopromazine Hydrochloride

1959 ◽  
Vol 105 (440) ◽  
pp. 811-814 ◽  
Author(s):  
J. G. Hegarty ◽  
A. R. Dabbs
Keyword(s):  
Field Trial ◽  
Psychotic Disorders ◽  
Small Population ◽  
Controlled Study ◽  
Previous Issue ◽  
Chronic Schizophrenic ◽  
Schizophrenic Patients

Vespral, chemically designated as 10-(3-dimethylaminopropyl-2-trifluoro-methyl)-phenothiazine hydrochloride, or trifluopromazine hydrochloride is a new ataractic drug which has only recently become available in this country. A clinical field trial with Vespral has been reported in a previous issue of this journal (1). It was then suggested that the drug was most effective in the treatment of psychotic disorders, schizophrenia in particular. The aim of this study was to evaluate, with some claim to objectivity, the effectiveness of the administration of trifluopromazine hydrochloride on the behaviour of a small population of chronic schizophrenic patients.

Cognitive impairment and negative symptoms in geriatric chronic schizophrenic patients: a follow-up study

1996 ◽  
Vol 22 (3) ◽  
pp. 223-231 ◽  
Author(s):  
Philip D. Harvey ◽  
Janel Lombardi ◽  
Martin Leibman ◽  
Leonard White ◽  
Michael Parrella ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Negative Symptoms ◽  
Chronic Schizophrenic ◽  
Follow Up Study ◽  
Schizophrenic Patients

Adjunctive fluoxetine in the treatment of negative symptoms in chronic schizophrenic patients

1994 ◽  
Vol 9 (4) ◽  
pp. 281-286 ◽  
Author(s):  
E. Spina ◽  
P. De Domenico ◽  
C. Ruello ◽  
N. Longobardo ◽  
C. Gitto ◽  
...  
Keyword(s):  
Negative Symptoms ◽  
Chronic Schizophrenic ◽  
Schizophrenic Patients

A Behavioural Training Programme for Chronic Schizophrenic Patients

1994 ◽  
Vol 165 (S24) ◽  
pp. 32-37 ◽  
Author(s):  
Feifei Li ◽  
Mingde Wang
Keyword(s):  
Negative Symptoms ◽  
Skills Training ◽  
Training Programme ◽  
Token Economy ◽  
Psychiatric Nurses ◽  
Control Group ◽  
Behavioural Treatment ◽  
Chronic Schizophrenic ◽  
Schizophrenic Patients ◽  
Experimental Group

This paper discusses the effectiveness of an in-patient rehabilitation programme administered by nurses that combines life skills training, active encouragement, and a token economy. Fifty-two chronic schizophrenic patients with prominent negative symptoms who had been continuously in hospital for at least a year were randomly assigned to the experimental or control group. The training and associated reinforcement schedule were administered daily to experimental subjects by two specially trained rehabilitation nurses. Control subjects did not receive training or reinforcement but were individually asked to perform the same daily tasks and participate in the same activities as the experimental-group subjects. Patients in both groups received their previous dosage of medication throughout the trial. After three months the severity of negative symptoms, as assessed by blind evaluators, decreased in both groups of subjects, but the improvement in the experimental group was much greater than that in the control group. These findings demonstrate the efficacy of behavioural interventions for chronic schizophrenic in-patients in China and highlight the importance of changing the role of Chinese psychiatric nurses from that of custodians who control patients' behaviour to that of therapists who provide psychological and behavioural treatment.

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