Benzodiazepines as oral premedication. A comparison between oxazepam, flunitrazepam, and placebo

1989 ◽  
Vol 84 (5) ◽  
pp. 868
Author(s):  
José Guerrerosantos ◽  
B. Hofstad
Keyword(s):  
2005 ◽  
Vol 15 (7) ◽  
pp. 554-559 ◽  
Author(s):  
BABITA GHAI ◽  
RADHIKA PRASAD GRANDHE ◽  
ARUN KUMAR ◽  
PRAMILA CHARI

2021 ◽  
Vol 10 (35) ◽  
pp. 2975-2979
Author(s):  
Aruna Vijay Chandak ◽  
Deepjit Bhuyan ◽  
Krishnendu S. ◽  
Vijay Chandak

BACKGROUND The perioperative habits contemplate showing that kids are in more danger of encountering fierce sedative enlistment and unfriendly social sequelae. In paediatric sedation, decent premedication is fundamental to lessen tension and disturbance in youngsters. Parental partition and odd operating room environment as a rule bring about blustery acceptance while giving general sedation. Narcotic premedication is vital for making kids quiet and cooperative in a weird environment. Our study was done to compare the efficacy of midazolam 0.5 mg / kg and triclofos sodium 100 mg / kg as oral premedications in children undergoing elective surgery. METHODS In this prospective randomised comparative study, sixty children posted for elective surgery were enrolled. The patients were randomly divided into midazolam group (Group M) and triclofos sodium group (Group T) of thirty each. Group M received oral midazolam 0.5 mg / kg 30 min before induction, and Group T received oral triclofos sodium 100 mg / kg 60 min before induction. All children were evaluated for level of sedation after premedication, behaviour at the time of separation from parents and at the time of mask placement for induction of anaesthesia. RESULTS Oral midazolam showed satisfactory sedation in children after premedication when compared to oral triclofos (P = 0.003). Both the drugs had a successful separation from parents, and the children were very cooperative during induction. No adverse effects attributable to the premedicants were seen. CONCLUSIONS Oral midazolam is better than triclofos sodium as a sedative anxiolytic in the paediatric population. KEY WORDS Anaesthesia, Hypnotics and Sedatives, Midazolam, Paediatrics, Premedication, Triclofos sodium


Anaesthesia ◽  
1977 ◽  
Vol 32 (4) ◽  
pp. 370-372 ◽  
Author(s):  
E. N. S. Fry ◽  
S. Deshpande
Keyword(s):  

Author(s):  
Satish Kumar ◽  
Sanjay Kumar

Background: Premedication is the administration of medication before anaesthesia. It is used to prepare the patient for anaesthesia and to provideoptimal conditions for surgery. Methods: The study of oral premedication dose of clonidine in spinal surgery at different time was conducted on sixty ASA grade-1 patients of eithersex between 20 to 60 years of age undergoing elective spine surgery. This study was performed after approval from ethics committee of the institute.Informed consent was obtained from each patient. Results: Sedation score was recorded preoperatively in both the groups when the patient were shifted to the operation theater according to score givenby American Society of Anaesthesia. In group-1, 25 patients (83.3%) had sedation score of 0 and 5 patients (16.7%) had score of 1. Similarly in group-2, 29 patients (96.7) had a sedation score 0 and only 1 patient (3.3%) had sedation score1. Conclusion: In conclusion this study establishes that the premedication with tab. clonidine 200µg (As tab. clonidine is available in 100µg) 90 minutebefore the surgery or 3.5 hour before the surgery produced adequate sedation Keywords: Clonidine, Sedation, Spine


2020 ◽  
Vol 37 (4) ◽  
pp. 520-523
Author(s):  
Krzysztof Specjalski ◽  
Lucyna Górska ◽  
Beata Wajda ◽  
Marta Chełmińska ◽  
Ewa Jassem

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