P8: Anaplastic Large Cell Lymphoma Arising in a Saline Breast Implant Capsule after Tissue Expander Breast Reconstruction

2006 ◽  
Vol 118 (Supplement) ◽  
pp. 92 ◽  
Author(s):  
Brian Olack ◽  
Raavi Gupta ◽  
Glen S. Brooks
2019 ◽  
Vol 143 ◽  
pp. 51S-58S ◽  
Author(s):  
Gregory A. Lamaris ◽  
Charles E. Butler ◽  
Anand K. Deva ◽  
Roberto N. Miranda ◽  
Kelly K. Hunt ◽  
...  

2019 ◽  
Vol 56 (1) ◽  
pp. 229-234
Author(s):  
Silviu Adrian Marinescu ◽  
Catalin Gheorghe Bejinariu ◽  
Carmen Giuglea

The worldwide increasing number of reports related to new cases of Breast Implant-associated Anaplastic Large Cell Lymphoma (BIA-ALCL) raises the interest of the scientific community in understanding the pathophysiology and the prognosis of these patients. This material presents the impact that BIA-ALCL exerts on the reconstructive options for patients who have undergone mastectomy. The research is based on data obtained from the analysis of a group of patients who have undergone 71 surgeries performed within the National Breast Reconstruction Program between 2015 and 2019. The statistical analysis revealed that 35.14% of the patients that were examined during the breast reconstruction consult refused the use of alloplastic techniques by invoking the potential associated risks described in the insufficient documentation of BIA-ALCL pathophysiology. Improving BIA-ALCL detection and reporting systems has led to an accelerated increase in the number of new diagnosed cases, determining the patients� reticence towards the use of alloplastic reconstructive techniques.


2018 ◽  
Vol 89 (12) ◽  
pp. 1679-1682
Author(s):  
Giuseppe Broggi ◽  
Fabio Motta ◽  
Andrea Angilello ◽  
Carlo Bortolussi ◽  
Gaetano Meli ◽  
...  

Materials ◽  
2018 ◽  
Vol 11 (12) ◽  
pp. 2393 ◽  
Author(s):  
Maria Mempin ◽  
Honghua Hu ◽  
Durdana Chowdhury ◽  
Anand Deva ◽  
Karen Vickery

Breast implantation either for cosmetic or reconstructive e purposes is one of the most common procedures performed in plastic surgery. Biofilm infection is hypothesised to be involved in the development of both capsular contracture and anaplastic large cell lymphoma (ALCL). Capsular contracture is one of the principal reasons for breast revision surgery and is characterised by the tightening and hardening of the capsule surrounding the implant, and ALCL is an indolent lymphoma found only in women with textured implants. We describe the types of breast implants available with regard to their surface characteristics of surface area and roughness and how this might contribute to capsular contracture and/or biofilm formation. The pathogenesis of capsular contracture is thought to be due to biofilm formation on the implant, which results in on-going inflammation. We describe the current research into breast implant associated ALCL and how implant properties may affect its pathogenesis, with ALCL only occurring in women with textured implants.


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