CLINICAL COURSE OF CYTOMEGALOVIRUS (CMV) VIREMIA WITH AND WITHOUT GANCICLOVIR TREATMENT IN CMV-SEROPOSITIVE RENAL TRANSPLANT RECIPIENTS: LONGITUDINAL STUDY OF CMV PP65 ANTIGENEMIA ASSAY

1998 ◽  
Vol 65 (12) ◽  
pp. S152
Author(s):  
C W Yang ◽  
Y O Kim ◽  
Y S Kim ◽  
S Y Kim ◽  
I S Moon ◽  
...  
1980 ◽  
Vol 25 (4) ◽  
pp. 320-322 ◽  
Author(s):  
A. B. MacLean ◽  
F. Sharp ◽  
J. D. Briggs ◽  
S. G. MacPherson

There are now many reported successful pregnancies to renal transplant recipients, but this is believed to be the first reported successful case of triplets. The clinical course, complications and management of the pregnancy are described.


2000 ◽  
Vol 38 (10) ◽  
pp. 3743-3745 ◽  
Author(s):  
Stephen K. N. Ho ◽  
Fu-Keung Li ◽  
Kar-Neng Lai ◽  
Tak-Mao Chan

We compared the CMV Brite Turbo Kit (BT) and the Digene Hybrid Capture CMV DNA (version 2.0) assay (HC2) in the quantitation of pp65 antigenemia and cytomegalovirus (CMV) DNA levels in immunosuppressed renal transplant recipients. Of 123 blood specimens collected from 24 renal transplant recipients, BT and HC2 assays detected 35 and 39 positive samples, respectively. The overall concordance rate between the two assays was 90%. Discordant results were observed at low levels of viremia, so that 8 samples were HC2 positive but BT negative and another 4 were BT positive but HC2 negative. There was good correlation (R 2 = 0.766; P < 0.01) between the levels of CMV DNA and pp65 antigenemia in the 31 concordant positive samples. Correlation between results obtained with the two assays was confirmed by longitudinal studies for a patient who developed clinical CMV disease. HC2 may be more sensitive at low viremia levels and allow earlier detection of impending CMV disease. The BT assay offered the advantage of a rapid (2-h) turnaround time. We conclude that BT and HC2 assays have similar sensitivity and efficacy in the diagnosis and monitoring of CMV infection and disease in renal transplant recipients. While the HC2 assay would be appropriate for centers that handle a large number of samples, the BT test may be more suitable for small sample numbers or when results are needed urgently.


2005 ◽  
Vol 5 (8) ◽  
pp. 1926-1933 ◽  
Author(s):  
C. Bressollette-Bodin ◽  
M. Coste-Burel ◽  
M. Hourmant ◽  
V. Sebille ◽  
E. Andre-Garnier ◽  
...  

1993 ◽  
Vol 6 (4) ◽  
pp. 185-190 ◽  
Author(s):  
GREGOR Bein ◽  
ANDREAS Bitsch ◽  
JOCHEM Hoyer ◽  
JIIRGEN Steinhoff ◽  
LUTZ Fricke ◽  
...  

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