CHIMERIC CELLS OF DONOR PHENOTYPE PRESENT IN LIVING RELATED RENAL TRANSPLANT RECIPIENTS INFUSED WITH DONOR MARROW AS POTENT REGULATORS OF RECIPIENT ANTI-DONOR IMMUNE RESPONSES.

2000 ◽  
Vol 69 (Supplement) ◽  
pp. S342
Author(s):  
James M. Mathew ◽  
Rolando Garcia-Morales ◽  
Laphalle Fuller ◽  
Theresa Vallone ◽  
Manuel Carreno ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Immune Responses ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Living Related

scholarly journals Human Cytomegalovirus-Encoded microRNAs Can Be Found in Saliva Samples from Renal Transplant Recipients

2020 ◽  
Vol 6 (4) ◽  
pp. 50
Author(s):  
Shelley Waters ◽  
Silvia Lee ◽  
Kylie Munyard ◽  
Ashley Irish ◽  
Patricia Price ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Immune Responses ◽  
Human Cytomegalovirus ◽  
Renal Transplant Recipients ◽  
Healthy Controls ◽  
Transplant Recipients ◽  
Host Immune Responses ◽  
Cell Responses ◽  
Hcmv Disease ◽  
Mirna Species

Human cytomegalovirus (HCMV) infections are common following renal transplantation and may have long-lasting effects. HCMV can be measured directly by viral DNA or indirectly via host immune responses. HCMV-encoded microRNA (miRNA) may alter the pathobiology of HCMV infections and contribute to the progression of HCMV disease. HCMV-encoded miRNAs can be detected in blood but have not been sought in saliva. We investigated saliva samples from 32 renal transplant recipients (RTR) and 12 seropositive healthy controls for whom immunological data was available. Five HCMV-encoded miRNAs (miR-UL112-5p, miR-US5-2-3p, miR-UL36, miR-US25-2-3p and miR-UL22A) were sought using primer probe assays. HCMV miRNA species were detected in saliva from 15 RTR and 3 healthy controls, with miR-US5-2-3p most commonly detected. The presence of HCMV miRNAs associated with increased T-cell responses to HCMV IE-1 in RTR, suggesting a link with frequent reactivations of HCMV.

Prophylactic deoxyspergualin treatment in living-related renal-transplant recipients transfused with donor-specific blood

2003 ◽  
Vol 75 (1) ◽  
pp. 60-66 ◽  
Author(s):  
Noritoshi Amada ◽  
Hajime Okazaki ◽  
Takaomi Sato ◽  
Shunji Miura ◽  
Yoichi Ohashi
Keyword(s):  
Renal Transplant ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Living Related
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