Cardiovascular Responses to the Cold Pressor Test in Exercise-Trained and Untrained Men

1988 ◽  
Vol 8 (12) ◽  
pp. 518-524 ◽  
Author(s):  
Paul J. Rogers ◽  
Alfred A. Bove ◽  
Ray W. Squires ◽  
Kent R. Bailey
Keyword(s):  
Cold Pressor Test ◽  
Cold Pressor ◽  
Cardiovascular Responses ◽  
Pressor Test

scholarly journals Blunted cardiovascular responses to exercise in Parkinson’s disease patients: role of the muscle metaboreflex

2018 ◽  
Vol 120 (4) ◽  
pp. 1516-1524 ◽  
Author(s):  
Jeann L. Sabino-Carvalho ◽  
André L. Teixeira ◽  
Milena Samora ◽  
Maurício Daher ◽  
Lauro C. Vianna
Keyword(s):  
Blood Pressure ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cold Pressor Test ◽  
Peripheral Resistance ◽  
Cold Pressor ◽  
Cardiovascular Responses ◽  
Group Differences ◽  
Muscle Metaboreflex ◽  
Pressor Test

Patients with Parkinson’s disease (PD) exhibit attenuated cardiovascular responses to exercise. The underlying mechanisms that are potentially contributing to these impairments are not fully understood. Therefore, we sought to test the hypothesis that patients with PD exhibit blunted cardiovascular responses to isolated muscle metaboreflex activation following exercise. For this, mean blood pressure, cardiac output, and total peripheral resistance were measured using finger photoplethysmography and the Modelflow method in 11 patients with PD [66 ± 2 yr; Hoehn and Yahr score: 2 ± 1 a.u.; time since diagnosis: 7 ± 1 yr; means ± SD) and 9 age-matched controls (66 ± 3 yr). Measurements were obtained at rest, during isometric handgrip exercise performed at 40% maximal voluntary contraction, and during postexercise ischemia. Also, a cold pressor test was assessed to confirm that blunted cardiovascular responses were specific to exercise and not representative of generalized sympathetic responsiveness. Changes in mean blood pressure were attenuated in patients with PD during handgrip (PD: ∆25 ± 2 mmHg vs. controls: ∆31 ± 3 mmHg; P < 0.05), and these group differences remained during postexercise ischemia (∆17 ± 1 mmHg vs. ∆26 ± 1 mmHg, respectively; P < 0.01). Additionally, changes in total peripheral resistance were attenuated during exercise and postexercise ischemia, indicating blunted reflex vasoconstriction in patients with PD. Responses to cold pressor test did not differ between groups, suggesting no group differences in generalized sympathetic responsiveness. Our results support the concept that attenuated cardiovascular responses to exercise observed in patients with PD are, at least in part, explained by an altered skeletal muscle metaboreflex. NEW & NOTEWORTHY Patients with Parkinson’s disease (PD) presented blunted cardiovascular responses to exercise. We showed that cardiovascular response evoked by the metabolic component of the exercise pressor reflex is blunted in patients with PD. Furthermore, patients with PD presented similar pressor response during the cold pressor test compared with age-matched controls. Altogether, our results support the hypothesis that attenuated cardiovascular responses to exercise observed in patients with PD are mediate by an altered skeletal muscle metaboreflex.

scholarly journals Stress-induced cardiovascular responses to cold pressortest in healthy young subjects

2020 ◽  
Vol 10 (2) ◽  
pp. 182-188
Author(s):  
Valeri Nikolov ◽  
Miroslava Petkova ◽  
Emil Nikolov
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Reactivity ◽  
Sleep Disturbances ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Cardiovascular Responses ◽  
Aortic Pulse Wave Velocity ◽  
Applanation Tonometry ◽  
Pressor Test ◽  
Young Subjects

Hypertension is one of the leading diseases of the cardiovascular system. It is manifested by changes in arterial stiffness. Cardiovascular reactivity, especially blood pressure (BP), changes during the cold pressor test (CPT) depending on various factors. Undoubtedly, stress is one of the most important factors. The aim of this study is to investigate the various effects of CPT on cardiovascular responses in healthy young subjects. A total of 56 healthy individuals aged between 21 and 26 years were investigated. The cardiovascular responses (BP, heart rate and aortic pulse wave velocity) to CPT were recorded by using the applanation tonometry. The Medical Outcomes Study Sleep Scale and the State-Trait Anxiety Inventory were used. 32.14% (n = 18) of the individuals who showed differences in systolic BP more than 22 mm Hg and differences in diastolic BP more than 18 mm Hg after the CPT were defined as hyperreactors. Hyperreactors showed a significantly higher increase in sleep disturbances (p > 0.01) and anxiety when compared to normoreactors. The CPT used to diagnose cardiovascular reactivity in young individuals and the assessment of perceived stress can help identify candidates who are at risk of hypertonic disease in the future.   Keywords: Cold pressor test, cardiovascular reactivity, applanation tonometry, blood pressure, stress.

Pupillary and cardiovascular responses to the cold-pressor test

1995 ◽  
Vol 55 (1-2) ◽  
pp. 45-49 ◽  
Author(s):  
Cristina Tassorelli ◽  
Giuseppe Micieli ◽  
Vera Osipova ◽  
Francesco Rossi ◽  
Giuseppe Nappi
Keyword(s):  
Cold Pressor Test ◽  
Cold Pressor ◽  
Cardiovascular Responses ◽  
Pressor Test

scholarly journals Attenuated Cardiovascular Responses to the Cold Pressor Test in Concussed Collegiate Athletes

2020 ◽  
Vol 55 (2) ◽  
pp. 124-131 ◽  
Author(s):  
Blair D. Johnson ◽  
James R. Sackett ◽  
Zachary J. Schlader ◽  
John J. Leddy
Keyword(s):  
Heart Rate ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Cold Pressor Test ◽  
Collegiate Athletes ◽  
Cold Pressor ◽  
Cardiovascular Responses ◽  
Pressor Test ◽  
Healthy Control ◽  
Peak Increase

Context Cardiovascular responses to the cold pressor test (CPT) provide information regarding sympathetic function. Objective To determine if recently concussed collegiate athletes had blunted cardiovascular responses during the CPT. Design Cross-sectional study. Setting Laboratory. Patients or Other Participants A total of 10 symptomatic concussed collegiate athletes (5 men, 5 women; age = 20 ± 2 years) who were within 7 days of diagnosis and 10 healthy control individuals (5 men, 5 women; age = 24 ± 4 years). Intervention(s) The participants' right hands were submerged in agitated ice water for 120 seconds (CPT). Main Outcome Measure(s) Heart rate and blood pressure were continuously measured and averaged at baseline and every 30 seconds during the CPT. Results Baseline heart rate and mean arterial pressure were not different between groups. Heart rate increased throughout 90 seconds of the CPT (peak increase at 60 seconds = 16 ± 13 beats/min; P &lt; .001) in healthy control participants but remained unchanged in concussed athletes (peak increase at 60 seconds = 7 ± 10 beats/min; P = .08). We observed no differences between groups for the heart rate response (P &gt; .28). Mean arterial pressure was elevated throughout the CPT starting at 30 seconds (5 ± 7 mm Hg; P = .048) in healthy control individuals (peak increase at 120 seconds = 26 ± 9 mm Hg; P &lt; .001). Mean arterial pressure increased in concussed athletes at 90 seconds (8 ± 8 mm Hg; P = .003) and 120 seconds (12 ± 8 mm Hg; P &lt; .001). Healthy control participants had a greater increase in mean arterial pressure starting at 60 seconds (P &lt; .001) and throughout the CPT than concussed athletes (peak difference at 90 seconds = 25 ± 10 mm Hg and 8 ± 8 mm Hg, respectively; P &lt; .001). Conclusions Recently concussed athletes had blunted cardiovascular responses to the CPT, which indicated sympathetic dysfunction.

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