Inhibition of Murine AIDS by Alternate Administration of Azidothymidine and Fludarabine Monophosphate

2000 ◽  
Vol 23 (3) ◽  
pp. 209-220 ◽  
Author(s):  
A. Fraternale ◽  
A. Casabianca ◽  
A. Tonelli ◽  
G. Vallanti ◽  
L. Chiarantini ◽  
...  
2000 ◽  
Vol 23 (3) ◽  
pp. 209-220 ◽  
Author(s):  
A. Fraternale ◽  
A. Casabianca ◽  
A. Tonelli ◽  
G. Vallanti ◽  
L. Chiarantini ◽  
...  

Author(s):  
Yukio Suruga ◽  
Masahiko Makino ◽  
Yoshiaki Okada ◽  
Hiromitsu Tanaka ◽  
Erik De Clercq ◽  
...  
Keyword(s):  

1998 ◽  
Vol 188 (2) ◽  
pp. 151-157 ◽  
Author(s):  
Mohamed Trebak ◽  
Charles A. Lambert ◽  
Souad Rahmouni ◽  
Serge Debrus ◽  
Marie-Paule Defresne ◽  
...  
Keyword(s):  

2012 ◽  
Vol 29 (4) ◽  
pp. 392-396 ◽  
Author(s):  
Milda Rudzianskiene ◽  
Rasa Griniute ◽  
Elona Juozaityte ◽  
Arturas Inciura ◽  
Viktoras Rudzianskas ◽  
...  

2002 ◽  
Vol 76 (24) ◽  
pp. 13106-13110 ◽  
Author(s):  
Kathy A. Green ◽  
W. James Cook ◽  
Arlene H. Sharpe ◽  
William R. Green

ABSTRACT C57BL/6 (B6) mice infected with LP-BM5 retroviruses develop disease, including an immunodeficiency similar to AIDS. This disease, murine AIDS (MAIDS), is inhibited by in vivo anti-CD154 monoclonal antibody treatment. The similar levels of insusceptibility of CD40−/− and CD154−/− B6 mice indicate that CD154/CD40 molecular interactions are required for MAIDS. CD4+ T and B cells, respectively, provide the CD154 and CD40 expression needed for MAIDS induction. Here, the required CD154/CD40 interaction is shown to be independent of CD80 and CD86 expression: CD80/CD86−/− B6 mice develop MAIDS after LP-BM5 infection.


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