Pycnogenol Supplementation Retards Immune Dysfunction in Murine AIDS (MAIDS) After LP-BM5 Leukemia Virus Infection by Modulating Cytokine Secretion

2005 ◽  
Vol 10 (2) ◽  
pp. 161-166
Author(s):  
Jeong-Min Lee ◽  
Kun-Young Park ◽  
Kwon-Tack Hwang ◽  
Ronald R. Watson
Keyword(s):  
Virus Infection ◽  
Leukemia Virus ◽  
Immune Dysfunction ◽  
Cytokine Secretion ◽  
Murine Aids

A Serological Study on Bovine Leukemia Virus Infection in Ten Provinces of Iran between 2010 and 2012

2012 ◽  
Vol 6 (3) ◽  
pp. 1-7 ◽  
Author(s):  
M Kazemimanesh ◽  
O Madadgar ◽  
MR Mahzoonieh ◽  
T Zahraei-Salehi ◽  
F Steinbach ◽  
...  
Keyword(s):  
Virus Infection ◽  
Bovine Leukemia Virus ◽  
Leukemia Virus ◽  
Bovine Leukemia Virus Infection ◽  
Serological Study

Effect of interferon on the exogenous friend murine leukemia virus infection

Virology ◽  
1982 ◽  
Vol 118 (1) ◽  
pp. 202-213 ◽  
Author(s):  
Charles H. Riggin ◽  
Paula M. Pithai
Keyword(s):  
Virus Infection ◽  
Murine Leukemia Virus ◽  
Leukemia Virus ◽  
Murine Leukemia

scholarly journals A role for elevated H-2 antigen expression in resistance to neoplasia caused by radiation-induced leukemia virus. Enhancement of effective tumor surveillance by killer lymphocytes.

1979 ◽  
Vol 149 (4) ◽  
pp. 898-909 ◽  
Author(s):  
D Meruelo
Keyword(s):  
Virus Infection ◽  
Leukemia Virus ◽  
Antigen Expression ◽  
Cell Surface Expression ◽  
Target Cells ◽  
Cell Mediated Immunity ◽  
Altered Expression ◽  
Radiation Induced ◽  
Low Levels

Resistance to neoplasia caused by radiation-induced leukemia virus (RadLV) is mediated by gene(s) in the H-2D region of the major histocompatibility complex. The previous observation that rapid increases in cellular synthesis and cell-surface expression of H-2 antigens are detectable immediately after virus inoculation has suggested that altered expression of H-2 antigens may play a significant role in the mechanism(s) of host defense to virus infection. This concept is supported by the following observations. First, cell-mediated immunity against RadLV transformed or infected cells can be detected with ease when H-2-positive target cells are used in the cell-mediated lympholysis (CML) assay. (Although RadLV transformed cells obtained from overtly leukemic animals and maintained in tissue culture are H-2 negative, these cells can regain their H-2 phenotype by in vivo passage in normal animals. The H-2-negative cells are poor targets in a CML assay.) Second, resistant mice develop greater numbers of effectors when infected with RadLV than do susceptible mice. Third, injection of normal (uninfected) thymocytes into syngeneic recipients of resistant or susceptible H-2 type does not stimulate a CML response. However, injection of RadLV infected thymocytes from resistant mice produces a vigorous CMI response, and such thymocytes elicit the strongest response at a time when both H-2 and viral antigen expression is elevated. By contrast, injection of infected thymocytes from susceptible mice, which express viral antigens, but low levels of H-2 antigens, does not stimulate a CML reaction. These findings may explain the easier induction of leukemia found by many investigators when virus is inoculated into neonatal mice and the preferential thymus tropism of some oncogenic type-C RNA virus. Cells expressing very low levels of H-2, such as thymocytes, may serve as permissive targets for virus infection because they lack an important component (H-2 antigens) of the dual or altered recognition signal required to trigger a defensive host immune response.

scholarly journals Persistent infection of rabbits with bovine leukemia virus associated with development of immune dysfunction.

1989 ◽  
Vol 63 (11) ◽  
pp. 4498-4506 ◽  
Author(s):  
C R Wyatt ◽  
D Wingett ◽  
J S White ◽  
C D Buck ◽  
D Knowles ◽  
...  
Keyword(s):  
Persistent Infection ◽  
Bovine Leukemia Virus ◽  
Leukemia Virus ◽  
Immune Dysfunction

scholarly journals trans-dominant interference with virus infection at two different stages by a mutant envelope protein of Friend murine leukemia virus.

1993 ◽  
Vol 67 (4) ◽  
pp. 2026-2033 ◽  
Author(s):  
T Matano ◽  
T Odawara ◽  
M Ohshima ◽  
H Yoshikura ◽  
A Iwamoto
Keyword(s):  
Virus Infection ◽  
Envelope Protein ◽  
Murine Leukemia Virus ◽  
Leukemia Virus ◽  
Murine Leukemia
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