Absent or Shortened Nasal Bone Length and the Detection of Down Syndrome in Second-Trimester Fetuses

2007 ◽  
Vol 109 (2, Part 1) ◽  
pp. 371-375 ◽  
Author(s):  
Elisa A. Gianferrari ◽  
Peter A. Benn ◽  
Lisa Dries ◽  
Kim Brault ◽  
James F. X. Egan ◽  
...  
2011 ◽  
Vol 204 (1) ◽  
pp. S143
Author(s):  
Jennifer McNamara ◽  
Harish Sehdev ◽  
Alison Cahill ◽  
Linda Odibo ◽  
George Macones ◽  
...  

2005 ◽  
Vol 25 (10) ◽  
pp. 906-911 ◽  
Author(s):  
Ron Maymon ◽  
Orna Levinsohn-Tavor ◽  
Howard Cuckle ◽  
Yosef Tovbin ◽  
Eli Dreazen ◽  
...  

2004 ◽  
Vol 191 (6) ◽  
pp. S45 ◽  
Author(s):  
Carolyn Zelop ◽  
Peter Benn ◽  
Elizabeth Milewski ◽  
Kimberly Brault ◽  
Adam Borgida ◽  
...  

2008 ◽  
Vol 34 (4) ◽  
pp. 518-523 ◽  
Author(s):  
Jeng-Hsiu Hung ◽  
Chong Yau Fu ◽  
Chih-Yao Chen ◽  
Kuan-Chong Chao ◽  
Jamie Hung

2012 ◽  
Vol 40 (S1) ◽  
pp. 157-158 ◽  
Author(s):  
A. Szabó ◽  
K. Szili ◽  
J. Szabó ◽  
D. Isaszegi ◽  
E. Horváth ◽  
...  

2005 ◽  
Vol 24 (11) ◽  
pp. 1487-1489 ◽  
Author(s):  
Carolyn M. Zelop ◽  
Elizabeth Milewski ◽  
Kimberly Brault ◽  
Peter Benn ◽  
Adam F. Borgida ◽  
...  

2007 ◽  
Vol 27 (2) ◽  
pp. 154-157 ◽  
Author(s):  
Eui Jung ◽  
Hye-Sung Won ◽  
Pil Ryang Lee ◽  
Ahm Kim

2006 ◽  
Vol 32 (4) ◽  
pp. 403-407 ◽  
Author(s):  
Takeshi Kanagawa ◽  
Hirotsugu Fukuda ◽  
Yukiko Kinugasa ◽  
Mihyon Son ◽  
Koichiro Shimoya ◽  
...  

2015 ◽  
Vol 38 (1) ◽  
pp. 48-54 ◽  
Author(s):  
F.I. Vos ◽  
E.A.P. De Jong-Pleij ◽  
M. Bakker ◽  
E. Tromp ◽  
C.M. Bilardo

Objectives: To evaluate trends of nasal bone length (NBL), prenasal thickness (PT), nuchal fold (NF), prenasal thickness to nasal bone length (PT-NBL) ratio, and prefrontal space ratio (PFSR), measured serially in second- and third-trimester Down syndrome (DS) fetuses. Methods: Prenatal databases were searched for cases of continuing DS pregnancies with serial measurements, taken at least two weeks apart. Trends were plotted on previously reported normal ranges. Results: Serial measurements were available in 25 Down syndrome fetuses. Median gestational age (GA) was 25 weeks; average number of visits per case was 2.44, with a median interval of 39 days between investigations. In DS fetuses, NBL and PT showed fairly stable trends with gestation. PFSR, but especially NF, had a more unpredictable trend. The PT-NBL ratio was the most stable marker, remaining unchanged in 95% of cases. NBL, PT, and NF showed more deviance from the normal range with advancing gestation, but MoM values remained stable. All but two fetuses had ultrasound markers or structural anomalies, especially heart defects. Conclusions: The PT-NBL ratio is the most constant DS marker throughout gestation, following a predictable trend.


2009 ◽  
Vol 34 (S1) ◽  
pp. 235-235
Author(s):  
F. I. Vos ◽  
E. A. de Jong-Pleij ◽  
E. Timmerman ◽  
L. R. Pistorius ◽  
E. Pajkrt ◽  
...  

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