Effects of Negative Middle Ear Pressure on Distortion Product Otoacoustic Emissions and Application of a Compensation Procedure in Humans

2009 ◽  
Vol 30 (2) ◽  
pp. 191-202 ◽  
Author(s):  
Xiao-Ming Sun ◽  
Mark D. Shaver
Keyword(s):  
Middle Ear ◽  
Otoacoustic Emissions ◽  
Distortion Product Otoacoustic Emissions ◽  
Distortion Product ◽  
Middle Ear Pressure

Relationships among Standard and Wideband Measures of Middle Ear Function and Distortion Product Otoacoustic Emissions

2011 ◽  
Vol 22 (05) ◽  
pp. 253-264 ◽  
Author(s):  
Kim S. Schairer ◽  
Brooke Morrison ◽  
Ellyn Szewczyk ◽  
Cynthia G. Fowler
Keyword(s):  
Middle Ear ◽  
Repeated Measures ◽  
Otoacoustic Emissions ◽  
Transfer Functions ◽  
Ambient Pressure ◽  
Normal Hearing ◽  
Distortion Product Otoacoustic Emissions ◽  
Distortion Product ◽  
Two Systems ◽  
The Relationship

Background: The overall goal of the current study was to examine the relationships among uncompensated admittance (Ya) at ambient pressure extracted from tympanograms, energy reflectance (ER) measures at ambient pressure from wideband acoustic transfer functions (WATF), and distortion product otoacoustic emissions (DPOAEs). If WATF measures of Ya are comparable to tympanometric measures of Ya at ambient pressure, it would be further evidence that the two systems provide comparable information at ambient pressure. Such a relationship could be used as a cross-check or validation for WATF measures and support the use of WATFs in lieu of tympanograms in some applications. Finally, if WATF measures of Ya and/or ER at DPOAE stimulus frequencies can account for some of the variability observed in DPOAE levels and/or signal-to-noise ratios (SNRs) in ears with normal hearing, the relationships could be used to improve hearing screening procedures. Purpose: The hypotheses were as follows: (1) measures of Ya at ambient pressure are significantly correlated as measured with tympanometric and WATF procedures and (2) measures of Ya and ER at DPOAE stimulus frequencies are significantly correlated with DPOAE level and SNR. Research Design: Repeated measures in human adults. Study Sample: Forty ears of 20 adults with normal hearing and middle ear function were included in the final sample. Data Collection and Analysis: Tympanograms were obtained using probe frequencies of 226, 678, and 1000 Hz; WATFs were obtained using a click probe, and DPOAEs were elicited with f2's of 1000, 2000, and 4000 Hz. A repeated measures analysis of variance (RM-ANOVA) was completed to identify significant differences between ears and among probe frequencies for Ya measured at ambient pressure from the Tympstar and for Ya measured at the three closest frequencies on the WATFs. Lines were fit to the comparison of Ya from the Tympstar and WATF, and percent variance accounted for (r2) was calculated. Ya and ER were extracted at all stimulus frequencies that were used to elicit DPOAEs and were compared to DPOAE levels and SNRs. RM-ANOVAs were completed to identify any significant differences in DPOAE level and SNR between ears and among f2 conditions. Lines were fit to the comparison of Ya and ER measures at f1 and f2 with the DPOAE levels and SNRs. The relationship between behavioral air conduction threshold at each f2 and DPOAE level (and SNR) was examined with regression analysis. Results: Ya was significantly correlated between the tympanometric and WATF measures at all three probe-tone frequencies. Ya and ER at f1 and f2 were significantly correlated with DPOAE level for f2 = 4000 Hz. Conclusions: The implications are as follows: (1) WATFs, which can be obtained with the same probe microphone system as DPOAEs, could be used as a supplement to tympanometry in a diagnostic test battery, and the relationship between Ya measured on the two systems could be used for verification, and (2) Ya and ER measures from WATFs at both DPOAE stimulus frequencies account for some of the variability observed in DPOAE levels at f2 = 4000 Hz in normal ears.

Safety and Efficacy of Topical Mitomycin C in Myringotomy Patency

2001 ◽  
Vol 124 (4) ◽  
pp. 368-373 ◽  
Author(s):  
David Jassir ◽  
Craig A. Buchman ◽  
Orlando Gomez-Marin
Keyword(s):  
Guinea Pig ◽  
Mitomycin C ◽  
Middle Ear ◽  
Otoacoustic Emissions ◽  
Saline Solution ◽  
Argon Laser ◽  
Distortion Product Otoacoustic Emissions ◽  
Safety And Efficacy ◽  
Distortion Product ◽  
Middle Ear Ventilation

OBJECTIVE: To develop an alternative method for prolonged middle ear ventilation using topical mitomycin C. STUDY DESIGN AND SETTING: Twenty guinea pigs with normal ears had bilateral myringotomies performed using the argon laser. After myringotomy, either mitomycin C (0.4 mg/mL) or saline pledgets were applied topically. Monitoring consisted of otomicroscopy and distortion-product otoacoustic emissions. RESULTS: Before myringotomy, all tympanic membranes were intact, and distortion-product otoacoustic emissions were measurable. After myringotomy, none (0%) of the saline-treated myringotomies were patent at day 7 as compared with 100% of the mitomycin C-treated myringotomies. At day 42, 10 (52.6%) of 19 mitomycin-treated myringotomies remained patent and 4 (28.6%) of 14 were patent at 131 days. Five (13.1%) ears developed purulent otorrhea; 3 were mitomycin C-treated and 2 were treated with saline solution. Distortion-product otoacoustic emissions testing did not document any evidence of ototoxicity. CONCLUSION: Topical mitomycin C appears to be safe and effective at prolonging the duration of myringotomy patency in the guinea pig. SIGNIFICANCE: Mitomycin C may be useful as an adjunct for preventing myringotomy closure.

High frequency distortion product otoacoustic emissions in children with and without middle ear dysfunction

2007 ◽  
Vol 71 (1) ◽  
pp. 125-133 ◽  
Author(s):  
Joseph Kei ◽  
Bronwyn Brazel ◽  
Kimberley Crebbin ◽  
Amber Richards ◽  
Natalie Willeston
Keyword(s):  
Middle Ear ◽  
High Frequency ◽  
Otoacoustic Emissions ◽  
Distortion Product Otoacoustic Emissions ◽  
Distortion Product

The Latency of Distortion Product Otoacoustic Emissions in Patients with Middle Ear Effusion

2006 ◽  
Vol 2 (2) ◽  
pp. 155-159
Author(s):  
Mee-Sook Lee ◽  
Wook Song ◽  
Hyun-Sook Jang ◽  
Ko-Jung Moon ◽  
Hee-Jong Chang
Keyword(s):  
Middle Ear ◽  
Otoacoustic Emissions ◽  
Distortion Product Otoacoustic Emissions ◽  
Middle Ear Effusion ◽  
Distortion Product ◽  
Ear Effusion

scholarly journals The influence of pressure compensation in the middle ear on the detection of distortion product otoacoustic emissions

2016 ◽  
Vol 15 (1) ◽  
pp. 43-62 ◽  
Author(s):  
Aleksandar Karić ◽  
Sanja Đoković ◽  
Nadežda Dimić ◽  
Svetlana Slavnić ◽  
Radomir Savić
Keyword(s):  
Middle Ear ◽  
Otoacoustic Emissions ◽  
Distortion Product Otoacoustic Emissions ◽  
Distortion Product ◽  
Pressure Compensation
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