Positron emission tomography in nonsmall cell lung cancer

2007 ◽  
Vol 19 (2) ◽  
pp. 78-83 ◽  
Author(s):  
Johan Vansteenkiste ◽  
Christophe Dooms
CHEST Journal ◽  
2005 ◽  
Vol 128 (4) ◽  
pp. 171S
Author(s):  
Rosemary F. Kelly ◽  
Vita V. Sullivan ◽  
Douglas B. Nelson ◽  
Amy M. Holmstrom ◽  
Frank A. Lederle ◽  
...  

Author(s):  
Hiroaki Nomori ◽  
Yoichi Machida ◽  
Ikuo Yamazaki ◽  
Koichi Honma ◽  
Ayumu Otsuki ◽  
...  

Abstract Background This study was aimed to examine the significance of fluorodeoxyglucose positron emission tomography in predicting prognosis after segmentectomy in lung cancer. Methods This was a retrospective cohort study, including 227 patients with cT1N0M0 nonsmall cell lung cancer who underwent positron emission tomography followed by segmentectomy between 2012 and 2019. Significance of tumor histology, T-stage, tumor size, and standardized uptake value on positron emission tomography in relation to recurrence-free survival were examined using Cox's proportional hazard analysis. Median follow-up period was 56 months (range: 1–95 months). Results Tumor stages were Tis in 25 patients, T1mi/T1a in 51, T1b in 98, and T1c in 53. Twenty-six patients (11%) experienced recurrences, including local (n = 8) and distant (n = 18). Multivariate analysis showed that the significant variables for recurrence-free survival were T-stage and standardized uptake value (p = 0.002 and 0.015, respectively), whereas tumor histology and tumor size were not significant (p = 0.28 and 0.44, respectively). When tumor size was divided into ≤2 cm and >2 cm for analysis, it was not significant again (p = 0.49), whereas standardized uptake value remained significant (p = 0.008). While standardized uptake value of tumors with recurrences was significantly higher than those without (4.9–2.8 and 2.6–2.5, respectively, p < 0.001), there was no significant difference between local and distant recurrences (p = 0.32). Cut-off value of standardized uptake value for recurrences was 3.2. Five-year recurrence-free survival rates in tumors with standardized uptake value <3.2 and ≥3.2 were 86 and 65%, respectively (p < 0.001). Conclusion Positron emission tomography could predict the prognosis after segmentectomy better than tumor size.


Cancer ◽  
2007 ◽  
Vol 110 (10) ◽  
pp. 2155-2168 ◽  
Author(s):  
Jeremy J. Erasmus ◽  
Homer A. Macapinlac ◽  
Stephen G. Swisher

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