The Impact of Resection Margin Status and Postoperative CA19-9 Levels on Survival and Patterns of Recurrence After Postoperative High-Dose Radiotherapy With 5-FU—Based Concurrent Chemotherapy for Resectable Pancreatic Cancer

2008 ◽  
Vol 31 (5) ◽  
pp. 446-453 ◽  
Author(s):  
Timothy J. Kinsella ◽  
Yuji Seo ◽  
Joseph Willis ◽  
Thomas A. Stellato ◽  
Christopher T. Siegel ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Resection Margin ◽  
Concurrent Chemotherapy ◽  
Margin Status ◽  
High Dose ◽  
Resectable Pancreatic Cancer ◽  
Resection Margin Status ◽  
The Impact ◽  
Patterns Of Recurrence

scholarly journals The impact of resection margin status on pancreatic cancer-associated survival: A meta-analysis

HPB ◽  
2016 ◽  
Vol 18 ◽  
pp. e130-e131
Author(s):  
I.E. Demir ◽  
C.A. Jäger ◽  
H. Friess ◽  
G.O. Ceyhan
Keyword(s):  
Pancreatic Cancer ◽  
Resection Margin ◽  
Meta Analysis ◽  
Margin Status ◽  
Resection Margin Status ◽  
The Impact

scholarly journals Redefining resection margin status in pancreatic cancer

HPB ◽  
2009 ◽  
Vol 11 (4) ◽  
pp. 282-289 ◽  
Author(s):  
Caroline S. Verbeke ◽  
Krishna V. Menon
Keyword(s):  
Pancreatic Cancer ◽  
Resection Margin ◽  
Margin Status ◽  
Resection Margin Status

Variability in Reporting Resection Margin Status in Pancreatic Cancer

2008 ◽  
Vol 247 (4) ◽  
pp. 716-717 ◽  
Author(s):  
Caroline S. Verbeke ◽  
Krishna V. Menon
Keyword(s):  
Pancreatic Cancer ◽  
Resection Margin ◽  
Margin Status ◽  
Resection Margin Status

scholarly journals The Impact of Intraoperative Frozen Section on Resection Margin Status and Survival of Patients Underwent Pancreatoduodenectomy for Distal Cholangiocarcinoma

2021 ◽  
Vol 11 ◽  
Author(s):  
Zhiqiang Chen ◽  
Bingran Yu ◽  
Jiaping Bai ◽  
Qiong Li ◽  
Bowen Xu ◽  
...  
Keyword(s):  
Median Survival ◽  
Statistical Difference ◽  
Resection Margin ◽  
Frozen Section ◽  
Margin Status ◽  
R0 Resection ◽  
Distal Cholangiocarcinoma ◽  
Intraoperative Frozen Section ◽  
Resection Margin Status ◽  
The Impact

BackgroundIntraoperative frozen section (FS) is broadly used during pancreaticoduodenectomy (PD) to ensure a negative margin status, but its survival benefits on obtaining a secondary R0 resection for distal cholangiocarcinoma (dCCA) is controversial and unclear.MethodsClinical data of 107 patients who underwent PD for dCCA was retrospectively collected and divided into different groups based on use of FS (FS and non-FS groups) and status of resection margin (pR0, sR0 and R1 groups), and clinical parameters and survival of patients were compared and analyzed accordingly.ResultsThere were 50 patients in FS group with a median survival of 28 months, 57 patients in non-FS group with a median survival of 27 months. There was no statistical difference between the two groups with Kaplan-Meier survival analysis (P = 0.347). There were 98 patients in R0 group (88 in pR0 and 10 in sR0) and nine patients in R1 group, with a median survival of 29 months and 22 months respectively, which showed a better survival in R0 group than in R1 group (P = 0.006). Survival analyses between subgroups revealed difference between pR0 and R1 group (P = 0.005), while no statistical difference concerning pR0 vs. sR0 (P = 0.211) and sR0 vs. R1 groups (P = 0.262). Multivariate Cox regression analysis revealed resection margin status, pre-operative biliary drainage and lymph node invasion to be independent prognostic factors for dCCA patients.ConclusionsIntraoperative FS should be recommended as it significantly increased the rate of R0 resection, which was positively related to a better survival. A primary R0 resection should also be encouraged and if not, a secondary R0 could be considered at the discretion of surgeons as it showed similar survival with primary R0 resection.

scholarly journals Prognosis of resected pancreatic cancer: is the refined resection margin status dispensable?

2012 ◽  
Vol 397 (6) ◽  
pp. 859-860 ◽  
Author(s):  
Werner Hartwig ◽  
Jens Werner ◽  
Markus W. Büchler
Keyword(s):  
Pancreatic Cancer ◽  
Resection Margin ◽  
Margin Status ◽  
Resection Margin Status

Impact of resection margin status on survival in pancreatic cancer patients after neoadjuvant treatment and pancreatoduodenectomy

Surgery ◽  
2020 ◽  
Vol 167 (5) ◽  
pp. 803-811 ◽  
Author(s):  
Shimpei Maeda ◽  
Alexandra M. Moore ◽  
Lavanya Yohanathan ◽  
Tatsuo Hata ◽  
Mark J. Truty ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Patients ◽  
Resection Margin ◽  
Neoadjuvant Treatment ◽  
Margin Status ◽  
Resection Margin Status

scholarly journals Impact of resection margin status on recurrence and survival in pancreatic cancer surgery

2019 ◽  
Vol 106 (8) ◽  
pp. 1055-1065 ◽  
Author(s):  
W. S. Tummers ◽  
J. V. Groen ◽  
B. G. Sibinga Mulder ◽  
A. Farina‐Sarasqueta ◽  
J. Morreau ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Resection Margin ◽  
Cancer Surgery ◽  
Margin Status ◽  
Resection Margin Status

Variability in Reporting Resection Margin Status in Pancreatic Cancer

2008 ◽  
Vol 247 (4) ◽  
pp. 717-718 ◽  
Author(s):  
Chandrajit P. Raut ◽  
Douglas B. Evans
Keyword(s):  
Pancreatic Cancer ◽  
Resection Margin ◽  
Margin Status ◽  
Resection Margin Status
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