scholarly journals Acquisition session length modulates consolidation effects produced by 5-HT2C ligands in a mouse autoshaping-operant procedure

2010 ◽  
Vol 21 (2) ◽  
pp. 83-89 ◽  
Author(s):  
Ellen A. Walker ◽  
John J. Foley
1971 ◽  
Vol 21 (4) ◽  
pp. 545-564 ◽  
Author(s):  
Richard W. Malott ◽  
Kay Malott ◽  
John G. Svinicki ◽  
Frederick Kladder ◽  
Ernest Ponicki

2018 ◽  
Vol 48 (5) ◽  
pp. 389-398 ◽  
Author(s):  
Gang Jee Ko ◽  
Yoshitsugu Obi ◽  
Melissa Soohoo ◽  
Tae Ik Chang ◽  
Soo Jeong Choi ◽  
...  

Background: The population of elderly end-stage renal disease patients initiating dialysis is rapidly growing. Although longer treatment is supposed to benefit for hemodialysis (HD) patients through more solute clearance and slower fluid removal, it is not yet clear how treatment session length affects mortality risk in octogenarians and nonagenarians. Methods: In a cohort of 112,026 incident HD patients between 2007 and 2011, we examined the association of treatment session length with all-cause mortality, adjusting for demographics and comorbid conditions. We also used restricted spline functions for age to evaluate continuous changes in the association of short (< 210 min) and extended (≥240 min) HD treatment (vs. 210 to < 240 min) with all-cause mortality over continuous age. Results: During the first 91 days of dialysis, patients aged ≥80 years tended to have the lowest treatment session length (median [interquartile range] 211 [193–230] min, r > 0.5). Longer treatment was associated with better survival in patients < 65 and 65 to < 80 years but not in octogenarians/nonagenarians. The association of extended treatment (≥240 min) with better survival was attenuated across age and not significant among patients aged ≥80 years with a hazard ratio of 1.10 (95% CI 0.99–1.20). Shorter treatment sessions (< 210 min) was associated with higher mortality across all age groups. Conclusion: Extended HD was not associated with lower mortality among octogenarians and nonagenarians, while it was associated with better survival among younger patients. Further studies are needed to determine the optimal treatment session length in elderly incident HD patients.


2019 ◽  
Vol 11 (21) ◽  
pp. 6127
Author(s):  
Maciej Bazanowski ◽  
Anna Szostak-Chrzanowski ◽  
Adam Chrzanowski

Extraction of underground minerals causes subsidence of the ground surface due to gravitational forces. The subsidence rate depends on the type of extracted ore, as well as its shape, thickness, and depth. Additionally, the embedding and overburden rock properties influence the time needed for the deformations to reach the surface. Using the results of geodetic deformation monitoring, which supply the information on pattern and magnitude of surface deformation, the performance of the mine may be evaluated. The monitoring can supply information on the actual rock mass behaviour during the operation and in many cases during the years after the mining operations have ceased. Geodetic methods of deformation monitoring supply information on the absolute and relative displacements (changes in position in a selected coordinate system) from which displacement and strain fields for the monitored object may be derived. Thus, geodetic measurements provide global information on absolute and relative displacements over large areas, either at discrete points or continuous in the space domain. The geodetic methods are affected by errors caused by atmospheric refraction and delay of electromagnetic signal. Since geodetic measurements allow for redundancy and statistical evaluation of the quality of the data, they generally provide reliable results. Usually, the designed accuracy of deformation measurements should allow for the detection of at least one third of the expected maximum deformations over the desired time span at the 95% probability level. In ground subsidence studies in mining areas, 10 mm accuracy at 95% level in both vertical and horizontal displacements is typically required. In the case of salt mines, the process of ground subsidence in viscous rock is slow; therefore, subsidence monitoring surveys may be performed once a year. In subsidence determination, two techniques are commonly used: leveling and satellite positioning. The satellite positioning technique is used to determine the 3D (horizontal coordinates and height) or 2D position of monitored points (only horizontal coordinates). When comparing the heights determined from satellite and leveling surveys, it has to be noted that the leveling heights are referred with respect to the geoid (orthometric heights), while heights determined from satellite surveys are referred with respect to the ellipsoid (ellipsoidal height). In the case of satellite surveys, the accuracy of horizontal position is typically 2–3 times better than vertical. The analysis of the optimal session duration lead to the conclusion that in order to achieve the sub-cm accuracy of horizontal coordinates at 95% confidence level, the satellite positioning session length using Global Positioning System (GPS) should be at least three hours long. In order to achieve the sub-cm accuracy of height coordinate at 95% confidence level in a single observation session, the GPS session length should be at least twelve hours long.


1978 ◽  
Vol 22 (1) ◽  
pp. 517-521
Author(s):  
Gordon H. Robinson ◽  
Thomas R. Jacobson

The argument is presented that we too often label human acts which lead to accidents as idiosyncratic rather than as part of the normal variability in expected performance and that this tendency impedes progress in understanding causation. Some choice reaction time data is examined in terms of variability as related to skill, work session length, alcohol stress, sleep deprivation and compatibility. Analytic distributions are examined as to their possible applicability and properties of their far right tails.


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