Endothelial Cell Loss and Central Corneal Thickness in Patients With and Without Diabetes After Manual Small Incision Cataract Surgery

Cornea ◽  
2011 ◽  
Vol 30 (4) ◽  
pp. 424-428 ◽  
Author(s):  
Priya Thomas Mathew ◽  
Sarada David ◽  
Nihal Thomas
2016 ◽  
Vol 7 (2) ◽  
pp. 124-134
Author(s):  
Rahul Bhargava ◽  
Shiv Kumar Sharma ◽  
Mini Chandra ◽  
Prachi Kumar ◽  
Yogesh Arora

Introduction: Endothelial cell loss and complications after cataract surgery may be higher when cataract is complicated by uveitis.Objective: To compare endothelial cell damage and complication rates after phacoemulsification and manual small incision cataract surgery (SICS) in patients with uveitis.Materials and methods: Patients with uveitic cataract were randomly allocated for phacoemulsification (n=75) or manual SICS (n=80) in a double blind prospective study. In the bag implantation of a hydrophobic acrylic intraocular lens was aimed in all cases. Patients with follow up of less than six months were excluded. Main outcome measures were alteration in endothelial cell counts (ECC) and morphology, improvement in vision and complication rates. ECC was measured preoperatively and at 1 week, 3 months and six months, postoperatively.Results: Six patients were lost to follow up and another three due inability to implant IOL. There were no significant difference in endothelial cell counts (P= 0.032), the variance of endothelial cell size (CV) and percentage of hexagonal cells between both the groups at six months (Mann-Whitney test, P=0.283). Endothelial cell density was significantly less in the group in which vitrectomy and/or pupil dilatation procedures were performed (2290±31.5 cells/mm2) versus (2385±50.3 cells/mm2), respectively (t test, P<0.001). Incidence of postoperative complications that were observed like persistent uveitis (P=0.591), macular edema (P=0.671) and PCO (P=0.678) and visual outcome (P=0.974) were comparable between the two groups.Conclusions: Manual SICS and phacoemulsification do not differ significantly in endothelial cell loss and complication rates in uveitic eyes. However, increased anterior chamber manoeuvring due to additional procedures may lead to significantly higher endothelial cell loss.


2016 ◽  
Vol 5 (73) ◽  
pp. 5410-5415
Author(s):  
Papineni Satyavani ◽  
Srinivas Prasad Killani ◽  
Atti Sri Hari ◽  
Superna Mahendra ◽  
Suneesha Gajula

1970 ◽  
Vol 3 (2) ◽  
pp. 177-180 ◽  
Author(s):  
SKD Thakur ◽  
A Dan ◽  
M Singh ◽  
A Banerjee ◽  
A Ghosh ◽  
...  

DOI: http://dx.doi.org/10.3126/nepjoph.v3i2.5273Nepal J Ophthalmol 2011; 3(2): 177-180


2010 ◽  
Vol 36 (2) ◽  
pp. 247-253 ◽  
Author(s):  
Parikshit Gogate ◽  
Prachi Ambardekar ◽  
Sucheta Kulkarni ◽  
Rahul Deshpande ◽  
Shilpa Joshi ◽  
...  

2015 ◽  
Vol 23 (2) ◽  
pp. 54 ◽  
Author(s):  
SomilN Jagani ◽  
AbhayA Lune ◽  
RenuM Magdum ◽  
AkashP Shah ◽  
Manisha Singh ◽  
...  

2021 ◽  
Vol 7 (3) ◽  
pp. 471-476
Author(s):  
Monika Dahiya ◽  
Gursimran Kaur ◽  
A K Khurana ◽  
Urmil Chawla

Phacoemulsification is a variant of extracapsular cataract extraction surgery which is the gold standard treatment modality for cataract surgery nowadays. The common nucleotomy techniques of phacoemulsification are divide and conquer, stop and chop and phaco chop.Aim of this studyto compare different techniques of nucleotomy during phacoemulsification with respect to corneal endothelial cell loss, central corneal thickness (CCT) and comment on their merits and demerits. 60 patients undergoing cataract surgery by phacoemulsification were randomly divided into three groups of 20 each (Group A, B and C) who underwent nucleotomy by divide and conquer, stop and chop and phaco chop technique respectively. The preoperative endothelial cell density and central corneal thickness were recorded using Topcon SP3000P non-contrast specular microscope. All patients were followed up at 1, 4 and 12week after surgery and evaluated for vision, slit lamp examination, endothelial cell count and central corneal thickness.The age group of patients studied was 50-80 years, where maximum number of patients were in 51-60 years age group. Out of 60 patients, most common morphological type of cataract was nuclear (40%) cataract followed by cortico-nuclear (36.67%) cataract. After 1 week of surgery, drop in endothelial cell density was 7.06% in Group A, 6.49% in Group B and 6.84% in Group C patients. A further slight decrease in endothelial cell count was recorded during 4week and on final follow up visit at 12 weeks after cataract surgery, there was an endothelial cell loss of 9.51%, 10.9% and 11% in Group A, B and C respectively. The central corneal thickness at 1postoperative week increased by 2.75%, 2.35% and 2.20% in group A, B and C respectively. Further evaluation of CCT at 4and 12 week after surgery showed the values to be almost same as preoperative values. The rate of complications, which mainly included postoperative keratitis, mild anterior uveitis and cystoid macular edema, were found to be almost the same in all the three study groups.All the three nucleotomy techniques of phacoemulsification i.e divide and conquer, stop and chop and phaco chop are equally efficacious in terms of CCT changes, endothelial cell loss and complications rate in the hands of an experienced surgeon.


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