In Vivo Three-Dimensional Corneal Epithelium Imaging in Normal Eyes by Anterior-Segment Optical Coherence Tomography

Cornea ◽  
2013 ◽  
Vol 32 (11) ◽  
pp. 1493-1498 ◽  
Author(s):  
Anastasios John Kanellopoulos ◽  
George Asimellis
Keyword(s):  
Optical Coherence Tomography ◽  
Corneal Epithelium ◽  
Anterior Segment ◽  
Three Dimensional ◽  
Optical Coherence

scholarly journals In Vivo Confocal Microscopy and Anterior Segment Optical Coherence Tomography Analysis of the Microcystic Keratitis

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Michał Dembski ◽  
Anna Nowińska ◽  
Klaudia Ulfik ◽  
Sławomir Teper ◽  
Edward Wylęgała
Keyword(s):  
Optical Coherence Tomography ◽  
Epithelial Cells ◽  
Confocal Microscopy ◽  
Corneal Epithelium ◽  
Anterior Segment ◽  
Corneal Stroma ◽  
Acute Stage ◽  
Optical Coherence ◽  
In Vivo Confocal Microscopy

Purpose. To describe the findings of in vivo confocal microscopy (IVCM) and anterior segment optical coherence tomography (AS-OCT) in a case of bilateral acute microcystic epitheliopathy after daily soft contact lens wear. Methods. IVCM and AS-OCT were used in the course of the bilateral epitheliopathy of a 23-year-old patient at the acute stage of the disease and at recovery after four days of treatment. The images were analyzed and compared. Results. On AS-OCT of the right eye, general hyperreflectivity and the increased thickness of the central corneal epithelium to 150 μm with numerous hyporeflective small, oval cysts were revealed and resolved completely at day 4 after diagnosis and treatment. AS-OCT scans of the left eye revealed oval shaped, hyperreflective material within the corneal epithelium. IVCM of both eyes showed numerous microcysts of different sizes filled with hyperreflective material mostly within superficial epithelial layers. Epithelial cells showed a polymorphism along with disruption of a cytoarchitecture. Basal epithelial cells and anterior stroma showed inflammatory changes. Posterior corneal stroma and endothelium presented normal morphology. Conclusions. Microcystic keratitis appeared as localized microcystic inflammation of epithelium on AS-OCT, which was confirmed by IVCM. Both IVCM and AS-OCT are helpful diagnostic instruments in case of cystic inflammation of corneal epithelium.

Characteristics of Linear Interstitial Keratitis by In Vivo Confocal Microscopy and Anterior Segment Optical Coherence Tomography

Cornea ◽  
2018 ◽  
Vol 37 (6) ◽  
pp. 785-788
Author(s):  
Aleksandra Petrovic ◽  
Kattayoon Hashemi ◽  
Frank Blaser ◽  
Wolfgang Wild ◽  
George Kymionis
Keyword(s):  
Optical Coherence Tomography ◽  
Confocal Microscopy ◽  
Anterior Segment ◽  
Optical Coherence ◽  
In Vivo Confocal Microscopy ◽  
Interstitial Keratitis

Uveo-scleral outflow pathways after ultrasonic cyclocoagulation in refractory glaucoma: an anterior segment optical coherence tomography and in vivo confocal study

2016 ◽  
Vol 100 (12) ◽  
pp. 1668-1675 ◽  
Author(s):  
Rodolfo Mastropasqua ◽  
Luca Agnifili ◽  
Vincenzo Fasanella ◽  
Lisa Toto ◽  
Lorenza Brescia ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Segment ◽  
Optical Coherence ◽  
Refractory Glaucoma

scholarly journals In Vivo Evaluation of the Limbus Using Anterior Segment Optical Coherence Tomography

2018 ◽  
Vol 7 (4) ◽  
pp. 12 ◽  
Author(s):  
Qihua Le ◽  
Daniel Cordova ◽  
Jianjiang Xu ◽  
Sophie X. Deng
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Segment ◽  
Optical Coherence ◽  
In Vivo Evaluation

Clinical and morphological manifestations of aniridia-associated keratopathy on anterior segment optical coherence tomography and in vivo confocal microscopy

2017 ◽  
Vol 15 (4) ◽  
pp. 759-769 ◽  
Author(s):  
Anna Voskresenskaya ◽  
Nadezhda Pozdeyeva ◽  
Tatyana Vasilyeva ◽  
Yevgeniy Batkov ◽  
Aleksandr Shipunov ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Confocal Microscopy ◽  
Anterior Segment ◽  
Optical Coherence ◽  
In Vivo Confocal Microscopy

scholarly journals Imaging depth extension of optical coherence tomography in rabbit eyes using optical clearing agents

2020 ◽  
Vol 245 (18) ◽  
pp. 1629-1636
Author(s):  
Ruiming Kong ◽  
Wenjuan Wu ◽  
Rui Qiu ◽  
Lei Gao ◽  
Fengxian Du ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Ex Vivo ◽  
Light Attenuation ◽  
Anterior Segment ◽  
Posterior Segment ◽  
Glycerol Solution ◽  
Optical Coherence ◽  
Optical Clearing ◽  
Imaging Depth

Optical coherence tomography has become an indispensable diagnostic tool in ophthalmology for imaging the retina and the anterior segment of the eye. However, the imaging depth of optical coherence tomography is limited by light attenuation in tissues due to optical scattering and absorption. In this study of rabbit eye both ex vivo and in vivo, optical coherence tomography imaging depth of the anterior and posterior segments of the eye was extended by using optical clearing agents to reduce multiple scattering. The sclera, the iris, and the ciliary body were clearly visualized by direct application of glycerol at an incision on the conjunctiva, and the posterior boundary of sclera and even the deeper tissues were detected by submerging the posterior segment of eye in glycerol solution ex vivo or by retro-bulbar injection of glycerol in vivo. The ex vivo rabbit eyes recovered to their original state in 60 s after saline-wash treatment, and normal optical coherence tomography images of the posterior segment of the sample eyes proved the self-recovery of in vivo performance. Signal intensities of optical coherence tomography images obtained before and after glycerol treatment were compared to analysis of the effect of optical clearing. To the best of our knowledge, this is the first study for imaging depth extension of optical coherence tomography in both the anterior and posterior segments of eye by using optical clearing agents.

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