A Comparative Study of the Water Drinking Test in Eyes With Open-Angle Glaucoma and Prior Trabeculectomy or Tube Shunt

2017 ◽  
Vol 26 (2) ◽  
pp. 119-125 ◽  
Author(s):  
Patricia Martinez ◽  
Valerie Trubnik ◽  
Benjamin E. Leiby ◽  
Sarah E. Hegarty ◽  
Reza Razeghinejad ◽  
...  
2018 ◽  
Vol 27 (11) ◽  
pp. 950-956 ◽  
Author(s):  
Carolina N. Susanna ◽  
Remo Susanna ◽  
Marcelo Hatanaka ◽  
Bianca N. Susanna ◽  
Fernanda N. Susanna ◽  
...  

2020 ◽  
pp. 112067212091133
Author(s):  
Izabela Almeida ◽  
Ana Luiza B Scoralick ◽  
Diego T Dias ◽  
Michele Ushida ◽  
Syril Dorairaj ◽  
...  

Purpose: To compare provocative test-based and long-term intraocular pressure variation parameters in patients with stable open-angle glaucoma. Methods: A prospective observational study was carried out in which stable open-angle glaucoma patients (⩾3 years of follow-up without any changes on current medical regimen) were consecutively enrolled. All patients were submitted to a water-drinking test. Long-term intraocular pressure parameters were obtained from isolated intraocular pressure measurements from each visit (⩾5 visits). We investigated the correlation and agreement between the following water-drinking test and long-term intraocular pressure parameters: mean, peak, and fluctuation. In addition, the percentage of eyes with significant intraocular pressure peaks during the water-drinking test (defined as a difference ⩾25% between water-drinking test intraocular pressure peak and mean long-term intraocular pressure) was assessed. Results: Sixty-three eyes from 63 open-angle glaucoma patients (mean age, 60.7 ± 11.8 years) were included. Mean and water-drinking test intraocular pressure peak correlated significantly with mean ( r = 0.67) and maximum long-term intraocular pressure ( r = 0.52), respectively ( p < 0.01). The correlation between water-drinking test intraocular pressure fluctuation and long-term intraocular pressure fluctuation was not significant ( p = 0.45). Limits of agreement from Bland–Altman plots exceeded the maximum allowed difference between methods (3 mm Hg) for all the intraocular pressure parameters analyzed, suggesting poor agreement between water-drinking test–derived and long-term intraocular pressure values. Overall, significant water-drinking test intraocular pressure peaks were observed in 39.7% of these eyes with stable open-angle glaucoma. Conclusion: Although some water-drinking test–based and long-term intraocular pressure parameters correlate significantly, water-drinking test results may not reflect the long-term intraocular pressure profile of stable open-angle glaucoma patients, as their agreement is poor. Many of these patients may experience significant water-drinking test intraocular pressure peaks, despite long-standing stable disease and unchanged medical regimen.


2005 ◽  
Vol 21 (3) ◽  
pp. 250-257 ◽  
Author(s):  
Michele Vetrugno ◽  
Dario Sisto ◽  
Tiziana Trabucco ◽  
Francesca Balducci ◽  
Nicola Delle Noci ◽  
...  

2017 ◽  
Vol 1 (3) ◽  
pp. 47-59
Author(s):  
Fauze A. Goncalves ◽  
Fernando Henrique R. Amorim ◽  
Camila S. Zangalli ◽  
Jose Paulo C. Vasconcellos ◽  
Vital P. Costa

Aim: To investigate whether the water-drinking test (WDT) and the postural-change test (PCT) can predict the 24-hour diurnal tensional curve (DTC) intraocular pressure (IOP) peak and fluctuation by assessing the correlation and agreement between these three tests in medically treated primary open-angle glaucoma (POAG) patients.Methods: 18 POAG patients underwent the DTC, WDT and PCT. Pearson’s correlation coefficient and Bland-Altman plots were used to assess the correlation and agreement between the results, respectively.Results: Mean DTC IOP peak was 18.72 + 4.31 mmHg and mean DTC IOP fluctuation was 7.00 + 2.54 mmHg. The IOP peak was outside office hours in 50% of the subjects. We observed poor correlations between the DTC and WDT fluctuations and the DTC and PCT fluctuations (r=-0.125, P=0.619; r=0.349, P=0.155, respectively). There was a moderate positive correlation between the DTC and WDT peaks (r=0.493, P=0.03) and a strong positive correlation between the DTC and PCT peaks (r=0.722, P<0.001). However, Bland-Altman plots demonstrated poor agreement between the IOP peaks and fluctuations between the 3 tests. WDT and DTC IOP peaks differed by 2 mmHg or more in 56% of the measurements. PCT and DTC IOP peaks showed that 83% of the measurements had differences greater than 2 mmHg.Conclusions: Despite moderate to strong correlations between DCT and WDT peaks and DTC and PCT IOP peaks, the agreement was generally poor, suggesting that they should be used with caution to estimate peak IOP.


QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Eman Sayed Ahmed ◽  
Mohammed Adel Abdelshafik ◽  
Momen Mahmoud Hamdi ◽  
Noha Mohsen Mahmoud

Abstract Background Glaucoma is a chronic optic neuropathy characterized by the excavation of the optic disc due to atrophy of the retinal ganglion cells. A progression of such atrophy leads to reduction of the visual field and eventually to the loss of sight at the end-stage of the disease, Glaucoma is the second leading cause of blindness worldwide Objectives To study the correlation between intraocular pressure (IOP) fluctuation during water drinking test (WDT) and the IOP fluctuation of modified diurnal tension curve (mDTC) in glaucomatous eyes Patients and Methods Fifty participants (24 males and 26 females) were recruited in this prospective study; forty participants with known Primary Open Angle Glaucoma and the other ten participants with non- glaucomatous healthy eyes which served as control. Patients attending the outpatient clinic at Al-Demerdash Hospital and Cairo Fatemic Hospital from October 2018 to March 2019 were prospectively recruited. Four IOP measurements were taken at 8:00 am, 12:00 pm, 4:00 pm and 8:00 pm which represented the mDTC, while WDT was represented by a single measurement of IOP before ingestion of one liter of water over five minutes, followed by three IOP measurements after ingestion of this amount of water at thirty minute intervals. Results Distribution of the studied participants as regards Age and sex: 50 participants were included in the this study. 40 presented the case group (20 males and 20 females) and the mean age of the case group was 54.7 years, 10 presented the control group(4 males and 6 females) and the mean age of the control group was 51.2years. 59% of participants had a peak IOP at 8:00 am, while 10% had a peak IOP at 12:00 pm, 6% at 4:00 pm and 25% of the participants had IOP peak at 8:00 pm during the mDTC. In the WDT, 96% of the participants had a peak IOP after 30 minutes of ingesting one liter of water, while 4% had a peak IOP after 60 minutes. None of the participants had IOP peak after 90 minutes of ingesting one liter of water.. The IOP fluctuations detected during the WDT were significantly correlated to fluctuations observed during the mDTC. Conclusion The data of this study suggested that WDT can be used as a useful provocative test for the detection of the diurnal IOP peaks and fluctuation observed in the glaucoma patients.


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