scholarly journals Protective ventilation in patients with acute respiratory distress syndrome related to COVID-19

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Chiara Mega ◽  
Irene Cavalli ◽  
Vito Marco Ranieri ◽  
Tommaso Tonetti
2019 ◽  
Vol 130 (4) ◽  
pp. 620-633 ◽  
Author(s):  
Tom Schepens ◽  
Ewan C. Goligher

A novel approach to ventilation aims to be both lung- and diaphragm-protective. This strategy integrates concerns over excessive lung stress during spontaneous breathing while avoiding both insufficient and excessive inspiratory effort.


JAMA ◽  
2013 ◽  
Vol 309 (7) ◽  
pp. 654 ◽  
Author(s):  
Brian M. Fuller ◽  
Nicholas M. Mohr ◽  
Christopher R. Carpenter

2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
Jed Lipes ◽  
Azadeh Bojmehrani ◽  
Francois Lellouche

Protective ventilation with low tidal volume has been shown to reduce morbidity and mortality in patients suffering from acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Low tidal volume ventilation is associated with particular clinical challenges and is therefore often underutilized as a therapeutic option in clinical practice. Despite some potential difficulties, data have been published examining the application of protective ventilation in patients without lung injury. We will briefly review the physiologic rationale for low tidal volume ventilation and explore the current evidence for protective ventilation in patients without lung injury. In addition, we will explore some of the potential reasons for its underuse and provide strategies to overcome some of the associated clinical challenges.


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