This chapter explores whether living donor liver transplant (LDLT) is morally permissible when the candidate is ineligible for a deceased donor liver transplant (DDLT). Two cases are evaluated: a woman with metastatic colorectal cancer (CRC) and a young female liver transplant recipient with a history of multiple suicide attempts who is in acute liver failure due to another intentional drug overdose. Although both women could benefit (gain life years) from liver transplant, neither is deemed eligible for DDLT by their transplant teams because of a short post-transplant life expectancy in the first case and expected poor organ stewardship in the second case. This chapter argues that LDLT is morally permissible in candidates ineligible for DDLT if the living donor provides a voluntary informed consent, knows he or she can withdraw at any time, and understands that the recipient candidate will not be listed for a DDLT should the LDLT fail.