Anterior Gradient 2 and Mucin 4 Expression Mirrors Tumor Cell Differentiation in Pancreatic Adenocarcinomas, But Aberrant Anterior Gradient 2 Expression Predicts Worse Patient Outcome in Poorly Differentiated Tumors

Pancreas ◽  
2014 ◽  
Vol 43 (1) ◽  
pp. 75-81 ◽  
Author(s):  
Veronika Brychtova ◽  
Marketa Hermanova ◽  
Petr Karasek ◽  
Jiri Lenz ◽  
Iveta Selingerova ◽  
...  
Keyword(s):  
Patient Outcome ◽  
Cell Differentiation ◽  
Tumor Cell ◽  
Poorly Differentiated ◽  
Tumor Cell Differentiation

scholarly journals Correlation Between Tumor Cell Differentiation and CEA Levels in Patients with Adenocarcinoma of the Rectum

2020 ◽  
Vol 52 (4) ◽  
Author(s):  
Reno Rudiman ◽  
Kiki Lukman ◽  
Tubagus Izzul Barr
Keyword(s):  
Cell Differentiation ◽  
Tumor Cell ◽  
Histopathological Examination ◽  
P Value ◽  
Stage Iiic ◽  
Serum Cea ◽  
Poorly Differentiated ◽  
The Mean ◽  
Well Differentiated ◽  
Tumor Cell Differentiation

Adenocarcinoma of the rectum is the most common colorectal cancer in Indonesia. This cancer has the highest recurrence after curative surgical therapy with or without adjuvant therapy. With the advancing modern histopathology and molecular biology, the prognosis after therapy can be predicted through surveillance using tumor cell differentiation and carcinoembryonic antigen (CEA). The aim of this study was to analyze the correlation between tumor cell differentiation and serum CEA level in patients with adenocarcinoma of the rectum in Dr. Hasan Sadikin General Hospital Bandung, Indonesia. This was a retrospective observational analytic study conducted from January 2018- January 2019. There were 36 patients involved in this study consisting of 3 patients (8.3%) diagnosed with Stage II, 10 patients (27.7%) with Stage IIIA, 20 patients (55.5%) with stage IIIB, and 3 patients (8.3%) with stage IIIC. On histopathological examination, it was demonstrated that19 patients (52.8%) were well-differentiated, 15 patients (41.7%) were moderately differentiated, and 2 patients (5.6%) were poorly differentiated. The mean CEA level (CI 95%) for well-differentiated patients before surgery was 138.18 (15.99-260.38) ng/ml while the same level for the moderately differentiated patients was 64.34 (34.34-163.02) ng/ml. The mean CEA level for poorly differentiated patients was 1.55 (6.71-9.81) ng / ml. The result of the Kruskal Wallis test showed a p-value of 0.004. There is a strong correlation between the level of tumor cell differentiation and CEA level.

scholarly journals Acetate supplementation restores chromatin accessibility and promotes tumor cell differentiation under hypoxia

2020 ◽  
Vol 11 (2) ◽  
Author(s):  
Yang Li ◽  
Joshua J. Gruber ◽  
Ulrike M. Litzenburger ◽  
Yiren Zhou ◽  
Yu Rebecca Miao ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Tumor Cell ◽  
Chromatin Accessibility ◽  
Tumor Cell Differentiation

Influence of in Vitro Culture Conditions on Tumor Cell Differentiation

1986 ◽  
Vol 72 (1) ◽  
pp. 15-20 ◽  
Author(s):  
Giuliana Porro ◽  
Elda Tagliabue ◽  
Sylvie Ménard ◽  
M.I. Colnaghi
Keyword(s):  
Cell Differentiation ◽  
Tumor Cell ◽  
In Vitro Culture ◽  
Culture Conditions ◽  
Tumor Cell Differentiation

CASP8 (rs3834129) and CASP3 (rs4647601) polymorphisms in oropharynx cancer risk, tumor cell differentiation, and prognosis in a cohort of the Brazilian population

2019 ◽  
Vol 46 (6) ◽  
pp. 6557-6563 ◽  
Author(s):  
Gabriela Arielo Tortorelli ◽  
Caroline Torricelli ◽  
Juliana Carron ◽  
Ericka Francislaine Dias Costa ◽  
Leisa Lopes-Aguiar ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Cancer Risk ◽  
Tumor Cell ◽  
Brazilian Population ◽  
Oropharynx Cancer ◽  
Tumor Cell Differentiation

scholarly journals NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma

Cell Reports ◽  
2020 ◽  
Vol 31 (12) ◽  
pp. 107782 ◽  
Author(s):  
Yan Cheng ◽  
Shengyou Liao ◽  
Gang Xu ◽  
Jian Hu ◽  
Duancheng Guo ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Tumor Cell ◽  
Tumor Cell Differentiation

The antitumor activity of the platinum complex D-17872 is associated with tumor cell differentiation

1993 ◽  
Vol 32 (2) ◽  
pp. 123-128 ◽  
Author(s):  
Hans Rainer Maurer ◽  
Christine Echarti ◽  
Rainer Voegeli ◽  
J�rg Pohl ◽  
Peter Hilgard
Keyword(s):  
Cell Differentiation ◽  
Antitumor Activity ◽  
Tumor Cell ◽  
Platinum Complex ◽  
Tumor Cell Differentiation

scholarly journals RANK Signaling Blockade Reduces Breast Cancer Recurrence by Inducing Tumor Cell Differentiation

2016 ◽  
Vol 76 (19) ◽  
pp. 5857-5869 ◽  
Author(s):  
Guillermo Yoldi ◽  
Pasquale Pellegrini ◽  
Eva M. Trinidad ◽  
Alex Cordero ◽  
Jorge Gomez-Miragaya ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Differentiation ◽  
Tumor Cell ◽  
Cancer Recurrence ◽  
Breast Cancer Recurrence ◽  
Rank Signaling ◽  
Tumor Cell Differentiation
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