Translocation and Expression of CSF1 in Pigmented Villonodular Synovitis, Tenosynovial Giant Cell Tumor, Rheumatoid Arthritis and Other Reactive Synovitides

2007 ◽  
Vol 31 (6) ◽  
pp. 970-976 ◽  
Author(s):  
John S. Cupp ◽  
Melinda A. Miller ◽  
Kelli D. Montgomery ◽  
Torsten O. Nielsen ◽  
John X. O??Connell ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Pigmented Villonodular Synovitis ◽  
Cell Tumor ◽  
Villonodular Synovitis ◽  
Tenosynovial Giant Cell Tumor ◽  
Pigmented Villonodular

scholarly journals Results of the surgical treatment of diffuse pigmented villonodular synovitis (diffuse-type tenosynovial giant-cell tumor) of the knee

2021 ◽  
Vol 23 (5) ◽  
pp. 656-663
Author(s):  
S. I. Herasymenko ◽  
O. A. Kostogryz ◽  
Yu. O. Kostogryz ◽  
A. M. Babko ◽  
V. M. Mayko
Keyword(s):  
Surgical Treatment ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Treatment Algorithm ◽  
State Institution ◽  
Pigmented Villonodular Synovitis ◽  
Cell Tumor ◽  
Villonodular Synovitis ◽  
Tenosynovial Giant Cell Tumor ◽  
Pigmented Villonodular

The aim. To develop a treatment algorithm with the aim of improving the treatment results of diffuse pigmented villonodular synovitis of the knee. To study and analyze the results of surgical treatment of diffuse pigmented villonodular synovitis of the knee. Materials and methods. The study was based on the results of treatment of 48 patients with pathohistologically verified diagnosis of diffuse pigmented villonodular synovitis (tenosynovial giant cell tumor) of the knee undergoing treatment at the State Institution “Institute of Traumatology and Orthopedics of the National Academy of Medical Sciences of Ukraine” from 2010 to 2019. Results. The best functional results can be achieved in patients with diffuse pigmented villonodular synovitis of the knee in stage I of the disease. Using the method of mathematical statistics to evaluate the results obtained, we see that scores obtained through the Lysholm Scoring Scale were statistically significantly different in stages before a surgery (P = 0.000782), 3 months (P = 0.00005) and 6 months after the surgery (P = 0.04); but over time, these differences diminished and became actually insignificant 12 months after the surgery (P = 0.89). Conclusions. Applying our therapeutic algorithm for the treatment of patients with diffuse pigmented villonodular synovitis of the knee, the outcome of the Lysholm score was excellent in 22 % of patients, good – in 45 %, satisfactory – in 21 % and poor – in 12 % of patients.

Concomitant Spondyloarthritis and Tenosynovial Giant Cell Tumor in Pigmented Villonodular Synovitis Challenging Cases

2018 ◽  
Vol 26 (5) ◽  
pp. e115-e117
Author(s):  
Mirko Manetti ◽  
Nicola Mondanelli ◽  
Irene Rosa ◽  
Lidia Ibba-Manneschi ◽  
Maurizio Benucci ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Pigmented Villonodular Synovitis ◽  
Cell Tumor ◽  
Villonodular Synovitis ◽  
Tenosynovial Giant Cell Tumor ◽  
Pigmented Villonodular

scholarly journals BILATERAL LOCALIZED PIGMENTED VILLONODULAR SYNOVITIS OF THE KNEE: CASE REPORT AND REVIEW

2018 ◽  
Vol 26 (3) ◽  
pp. 183-186
Author(s):  
TIAGO LAZZARETTI FERNANDES ◽  
LIVIA DAU VIDEIRA ◽  
SANDRA UMEDA SASAKI ◽  
RENATO JOSÉ MENDONÇA NATALINO ◽  
ADRIANO MARQUES DE ALMEIDA ◽  
...  
Keyword(s):  
Case Report ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Case Series ◽  
Pigmented Villonodular Synovitis ◽  
Cell Tumor ◽  
Villonodular Synovitis ◽  
Tenosynovial Giant Cell Tumor ◽  
Localized Pigmented Villonodular Synovitis ◽  
Pigmented Villonodular

ABSTRACT Objectives Several cases of bilateral diffuse pigmented villonodular synovitis (PVNS) or tenosynovial giant cell tumor have been described in the literature. Nevertheless, some presentations are rare and differential diagnoses are necessary. Methods The purpose of this study was to perform a systematic review of the literature related to PVNS and to report a rare supra-patellar bilateral and focal presentation. We performed a systematic data review in the Pubmed Clinical Queries database using MeSH and keywords related to PVNS and tenosynovial giant cell tumor. Results Two cases of bilateral and local PVNS had been previously described, but neither was localized in the supra-patellar compartment. To our knowledge, this case report is the first to describe supra-patellar bilateral and localized PVNS of the knee. This case involves a 28 -year-old woman with bilateral localized PVNS of the supra-patellar recess of the knee. MRI showed a low-signal intensity nodule in T1- and T2-weighted images. These were associated with hemosiderin pigmentation. Conclusion The most important finding of the case reported is related to rarity and location. Histopathology analysis confirmed a rare case of hemosiderin pigmentation in the capsular nodule with internal non-pigmented villous content. Lipoma arborescens in the supra-patellar form must be ruled out as a differential diagnosis since it occurs in the same site. Level of Evidence IV; Case series.

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