A Multicentric Comparison of Apparent Diffusion Coefficient Mapping and the Kaiser Score in the Assessment of Breast Lesions

Background: It is very important for surgeons to know the accurate borders of malignant bone tumors before they can precisely resect the tumors. The objective of the study is to investigate the usefulness of apparent diffusion coefficient value for estimating the extent of malignant bone tumor. Methods: VX2 tumor fragments were implanted into the tibiae of 30 rabbits. After 4 weeks, magnetic resonance plain scans were performed and then tumor specimens were cut into sagittal sections and partitioned into histology slices for dot-to-dot comparisons with microscopic findings. The sizes of the tumors measured separately on specimen, conventional magnetic resonance imaging sequences, and diffusion-weighted imaging (by measuring apparent diffusion coefficient value on apparent diffusion coefficient mapping) were compared statistically with each other. Results: The mean tumor sizes measured on specimen and apparent diffusion coefficient mapping (by calculating apparent diffusion coefficient value) were 5.20 ± 0.89 cm and 5.31 ± 0.87 cm, respectively; there was no significant difference between the 2 ( P > .05). The tumor sizes measured on T1WI, T2WI, T2WI with fat suppression were 4.82 ± 0.87 cm, 5.58 ± 0.87 cm, 5.63 ± 0.85 cm, respectively, and these values were significantly different from that measured on specimen (5.20 ± 0.89 cm, P < .05). Conclusion: The extent of the VX2 malignant bone tumor can be estimated accurately by measurement of apparent diffusion coefficient value.

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Reperfusion demonstrated by apparent diffusion coefficient mapping after local intra-arterial thrombolysis for ischaemic stroke

Neuroradiology ◽

10.1007/s002340100555 ◽

2001 ◽

Vol 43 (7) ◽

pp. 591-594 ◽

Cited By ~ 20

Author(s):

M. Taleb ◽

K. O. Lövblad ◽

M. El-Koussy ◽

R. Guzman ◽

C. Bassetti ◽

...

Keyword(s):

Diffusion Coefficient ◽

Apparent Diffusion Coefficient ◽

Ischaemic Stroke ◽

Apparent Diffusion ◽

Apparent Diffusion Coefficient Mapping ◽

Arterial Thrombolysis

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Magnetic Resonance Diffusion W Imaging in Cerebral Fat Embolism

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques ◽

10.1017/s0317167100003565 ◽

2004 ◽

Vol 31 (3) ◽

pp. 417-421 ◽

Cited By ~ 13

Author(s):

G.B. Marshall ◽

V.R. Heale ◽

L. Herx ◽

A. Abdeen ◽

L. Mrkonjic ◽

...

Keyword(s):

Cell Death ◽

Diffusion Coefficient ◽

Magnetic Resonance ◽

Apparent Diffusion Coefficient ◽

Diffusion Weighted Imaging ◽

Fat Embolism ◽

Cytotoxic Edema ◽

Apparent Diffusion ◽

Weighted Sequences ◽

Apparent Diffusion Coefficient Mapping

The use of diffusion weighted imaging with apparent diffusion coefficient mapping in the diagnosis of cerebral fat embolism is shown here to demonstrate infarcts secondary to fat emboli more intensely than T2 weighted sequences 24 hours after the onset of symptoms. Embolic foci are hypointense on apparent diffusion coefficient mapping consistent with cytotoxic edema associated with cell death and restricted water diffusion. This technique increases the sensitivity for detecting cerebral fat embolism and offers a potentially important tool in its diagnosis.

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