Adipose-Derived Stem Cells Seeded on Acellular Dermal Matrix Grafts Enhance Wound Healing in a Murine Model of a Full-Thickness Defect

2012 ◽  
Vol 69 (6) ◽  
pp. 656-662 ◽  
Author(s):  
Sheng-Ping Huang ◽  
Chia-Chun Hsu ◽  
Shun-Cheng Chang ◽  
Chih-Hsin Wang ◽  
Shou-Cheng Deng ◽  
...  
Keyword(s):  
Stem Cells ◽  
Wound Healing ◽  
Murine Model ◽  
Acellular Dermal Matrix ◽  
Adipose Derived Stem Cells ◽  
Full Thickness ◽  
Dermal Matrix ◽  
Acellular Dermal ◽  
Enhance Wound Healing

Denatured acellular dermal matrix seeded with bone marrow mesenchymal stem cells for wound healing in mice

Burns ◽  
2019 ◽  
Vol 45 (7) ◽  
pp. 1685-1694 ◽  
Author(s):  
Yongjun Qi ◽  
Zhengxue Dong ◽  
Hongzhen Chu ◽  
Qi Zhao ◽  
Xiao Wang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Wound Healing ◽  
Mesenchymal Stem Cells ◽  
Acellular Dermal Matrix ◽  
Dermal Matrix ◽  
Marrow Mesenchymal Stem Cells ◽  
Acellular Dermal

scholarly journals Acellular dermal matrix treats lower extremity full-thickness skin defect on one-stage without skin graft or flaps

2020 ◽  
Author(s):  
Gongchi Li ◽  
Pan Zhou ◽  
Hanlin Liu ◽  
Han Peng ◽  
Binghui Li ◽  
...  
Keyword(s):  
Wound Healing ◽  
Lower Extremity ◽  
Skin Graft ◽  
Lower Extremities ◽  
Acellular Dermal Matrix ◽  
Matrix Product ◽  
Skin Defect ◽  
Full Thickness ◽  
Dermal Matrix ◽  
Acellular Dermal

Abstract Background Self-repair of lower limb wounds has always been one of the research hotspots. Flaps and skin graft are the preferred treatment for lower extremity wound reconstruction. However, these treatments have many disadvantages, such as secondary damage, poor healing quality. In recent years, the use of acellular dermal matrix has emerged as an alternative treatment option for extremity ulcers. Methods This study aimed to explore whether acellular dermal matrix can be used as a single treatment to promote wound healing. 7 patients with lower extremities cutaneous deficiency exposing bone or tendon, was covered by Pelnac, which was an acellular dermal matrix product approved by China Food and Drug Administration. All the wound was treated by Pelnac without flaps and skin graft. The external dressing was changed every 10 days. Results After a maximum of 20 weeks, all the wounds were completely healed. During the 12 months follow-up period none of the patients developed skin wear on the treatment area. All patients maintained their postoperative ambulatory ability. All patients were satisfied with the appearance and feeling after wound healing. Conclusions These findings may mean acellular dermal matrix is a novel method offering opportunity for treatment of lower extremities cutaneous deficiency exposing bone or tendon. It also has the potential to close wounds of all uninfected, non-ischemic, full-thickness cutaneous deficiency.

Acellular Dermal Matrix Seeded with Adipose-Derived Stem Cells as a Subcutaneous Implant

2011 ◽  
Vol 35 (5) ◽  
pp. 756-763 ◽  
Author(s):  
Hakan Orbay ◽  
Yoshihiro Takami ◽  
Hiko Hyakusoku ◽  
Hiroshi Mizuno
Keyword(s):  
Stem Cells ◽  
Acellular Dermal Matrix ◽  
Adipose Derived Stem Cells ◽  
Dermal Matrix ◽  
Acellular Dermal ◽  
Subcutaneous Implant

Human Adipose-Derived Stem Cells Adhere to Acellular Dermal Matrix

2008 ◽  
Vol 32 (4) ◽  
pp. 698-699 ◽  
Author(s):  
A. M. Altman ◽  
E. S. Chiu ◽  
X. Bai ◽  
Y. Yan ◽  
Y. H. Song ◽  
...  
Keyword(s):  
Stem Cells ◽  
Acellular Dermal Matrix ◽  
Adipose Derived Stem Cells ◽  
Dermal Matrix ◽  
Acellular Dermal
Sign in / Sign up

Export Citation Format

Share Document