Fresh frozen plasma resuscitation attenuates platelet dysfunction compared with normal saline in a large animal model of multisystem trauma

2014 ◽  
Vol 76 (4) ◽  
pp. 998-1007 ◽  
Author(s):  
Martin Sillesen ◽  
Pär I. Johansson ◽  
Lars S. Rasmussen ◽  
Guang Jin ◽  
Cecilie H. Jepsen ◽  
...  
1982 ◽  
Vol 4 (1) ◽  
pp. 27-27

A reader commented:"In the October issue of PIR(3:121, 1981), in "Necrotizing Entercolitis" Burg and Polin recommend partial exchange transfusion for high hematocrit, using normal saline. I was taught to use fresh frozen plasma or albumin for partial exchanges. What are the advantages, if any, of isotonic saline over plasma or albumin?" Drs Burg and Polin reply: "Although, theoretical arguments can be made for use of fresh frozen plasma to reduce the hematocrit, either saline, synthetic plasma expanders, or 5% albumin would be suitable. Much of the albumin given in plasma or synthetic solutions quickly leaks out of the newborn infant's intravascular compartment. The purpose of a partial exchange transfusion in neonatal polycythemia is to lower the hematocrit and lessen the hyperviscosity; it is not to replace coagulation or immune factors or remove toxins. Saline would be just as satisfactory as plasma for this purpose."


Nitric Oxide ◽  
2021 ◽  
Author(s):  
Barbara Adamik ◽  
Claes Frostell ◽  
Urszula Paslawska ◽  
Barbara Dragan ◽  
Stanislaw Zielinski ◽  
...  

2020 ◽  
Vol 7 (3) ◽  
pp. A142-146
Author(s):  
Lata . Lata . ◽  
◽  
Manju Kumari ◽  
Sachin Kolte ◽  
Rashmi Arora ◽  
...  

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