Improvements in Early Mortality and Coagulopathy are Sustained Better in Patients With Blunt Trauma After Institution of a Massive Transfusion Protocol in a Civilian Level I Trauma Center

2009 ◽  
Vol 66 (6) ◽  
pp. 1616-1624 ◽  
Author(s):  
Christopher J. Dente ◽  
Beth H. Shaz ◽  
Jeffery M. Nicholas ◽  
Robert S. Harris ◽  
Amy D. Wyrzykowski ◽  
...  
Keyword(s):  
Blunt Trauma ◽  
Trauma Center ◽  
Massive Transfusion ◽  
Early Mortality ◽  
Massive Transfusion Protocol ◽  
Level I ◽  
Transfusion Protocol

scholarly journals Effects of Massive Transfusion Protocol Implementation in Trauma Patients at a Level I Trauma Center

2020 ◽  
Vol 33 (2) ◽  
pp. 74-80
Author(s):  
Hyun Woo Sun ◽  
Sang Bong Lee ◽  
Sung Jin Park ◽  
Chan Ik Park ◽  
Jae Hun Kim
Keyword(s):  
Trauma Center ◽  
Massive Transfusion ◽  
Trauma Patients ◽  
Protocol Implementation ◽  
Massive Transfusion Protocol ◽  
Level I ◽  
Transfusion Protocol

Improvement of Treatment Outcomes after Implementation of a Massive Transfusion Protocol: A Level I Trauma Center Experience

2017 ◽  
Vol 83 (4) ◽  
pp. 394-398 ◽  
Author(s):  
Andrew Nunn ◽  
Peter Fischer ◽  
Ronald Sing ◽  
Megan Templin ◽  
Michael Avery ◽  
...  
Keyword(s):  
Length Of Stay ◽  
Trauma Center ◽  
Massive Transfusion ◽  
Unit Length ◽  
Hospital Length Of Stay ◽  
Modest Improvement ◽  
Massive Transfusion Protocol ◽  
Fresh Frozen ◽  
Level I ◽  
Transfusion Protocol

We assessed the effectiveness of the implementation of an institutional massive transfusion protocol (MTP) for resuscitation with a 1:1:1 transfusion ratio of packed red blood cell (PRBC), fresh frozen plasma, and platelet units. In a Level I trauma center database, all trauma admissions (2004–2012) that received massive transfusions (≥10 units PRBCs in the first 24 hours) were reviewed retrospectively. Demographic data, transfusion ratios, and outcomes were compared before (PRE) and after (POST) MTP implementation in May 2008. Age, sex, and mechanism of injury were similar between 239 PRE and 208 POST trauma patients requiring massive transfusion. Transfusion ratios of fresh frozen plasma:PRBC and platelet:PRBC increased after MTP implementation. Among survivors, MTP implementation shortened hospital length of stay from 31 to 26 days (P = 0.04) and intensive care unit length of stay from 31 to 26 days (P = 0.02). Linear regression identified treatment after (versus before) implementation of MTP as an independent predictor of decreased ventilator days after adjusting for age, Glasgow Coma Scale, and chest Abbreviated Injury Score (P < 0.0001). Modest improvement in ratios likely does not account for all significant improvements in outcomes. Implementing a standardized protocol likely impacts automation, efficiency, and/or timeliness of product delivery.

scholarly journals Evaluation of massive transfusion protocol practices by type of trauma at a level I trauma center

2018 ◽  
Vol 21 (5) ◽  
pp. 261-266 ◽  
Author(s):  
Roshan Givergis ◽  
Swapna Munnangi ◽  
Katayoun Fayaz M Fomani ◽  
Anthony Boutin ◽  
Luis Carlos Zapata ◽  
...  
Keyword(s):  
Trauma Center ◽  
Massive Transfusion ◽  
Massive Transfusion Protocol ◽  
Level I ◽  
Transfusion Protocol

Intraoperative Resuscitation by Specialized Trauma Nurse Clinicians Improves Adherence to Massive Transfusion Protocol

2020 ◽  
Vol 86 (1) ◽  
pp. 35-41
Author(s):  
L. Andrew May ◽  
Kevin N. Harrell ◽  
Christopher M. Bell ◽  
Angela Basham-Saif ◽  
Donald E. Barker ◽  
...  
Keyword(s):  
Blood Product ◽  
Trauma Registry ◽  
Massive Transfusion ◽  
Blood Products ◽  
Packed Red Blood Cells ◽  
Massive Blood Loss ◽  
Massive Transfusion Protocol ◽  
Nurse Clinicians ◽  
Level I ◽  
Transfusion Protocol

A massive transfusion protocol (MTP) was implemented at a Level I trauma center in 2007 for patients with massive blood loss. A goal ratio of plasma to pheresed platelets to packed red blood cells (PRBCs) of 1:1:1 was established. From 2007 to 2014, trauma nurse clinicians (TNCs) administered the MTP during initial resuscitation and anesthesia personnel administered the MTP intraoperatively. In 2015, TNCs began administering the MTP intraoperatively. This study evaluates intraoperative blood product ratios and crystalloid volume administered by anesthesia personnel or TNCs. A retrospective review of trauma registry patients requiring MTP from 2007 to 2017 was performed. Patient data were stratified according to MTP administration by either anesthesia personnel (2007–2015) or TNCs (2015–2017). Ninety-seven patients were included with 54 anesthesia patients and 44 TNC patients. Patients undergoing resuscitation by MTP administered by TNCs received less median crystalloid (3000 mL vs 1500 mL, P < 0.001). The ratio of plasma:PRBC (0.75 vs 0.93, P = 0.027) and platelets:PRBC (0.75 vs 1.04, P = 0.003) was found to be significantly closer to 1:1 for TNC patients. MTP intraoperative blood product administration by TNCs reduced the amount of infused crystalloid and improved adherence to MTP in achieving a 1:1:1 ratio of blood products.

Cost-effectiveness of using recombinant factor VIIa (rFVIIa) in a massive transfusion protocol for severe blunt trauma

2011 ◽  
Vol 213 (3) ◽  
pp. S116 ◽  
Author(s):  
Mayur B. Patel ◽  
Judson B. Williams ◽  
Syamal D. Bhattacharya ◽  
Richard S. Miller ◽  
John A. Morris ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Blunt Trauma ◽  
Massive Transfusion ◽  
Recombinant Factor Viia ◽  
Factor Viia ◽  
Massive Transfusion Protocol ◽  
Transfusion Protocol

Implementation of Trauma Center and Massive Transfusion Protocol Improves Outcomes for Major Trauma Patients: A Study at a Single Institution in Korea

2017 ◽  
Vol 42 (7) ◽  
pp. 2067-2075 ◽  
Author(s):  
Kyungjin Hwang ◽  
Junsik Kwon ◽  
Jayun Cho ◽  
Yunjung Heo ◽  
John Cook-Jong Lee ◽  
...  
Keyword(s):  
Trauma Center ◽  
Major Trauma ◽  
Massive Transfusion ◽  
Trauma Patients ◽  
Single Institution ◽  
Massive Transfusion Protocol ◽  
Transfusion Protocol

scholarly journals No impact of a massive transfusion protocol on coagulopathy and mortality at a level 1 trauma center: why?

Critical Care ◽  
2012 ◽  
Vol 16 (S1) ◽  
Author(s):  
C Bourassa-Fulop ◽  
J Chauny ◽  
J Paquet ◽  
R Daoust ◽  
E Notebaert
Keyword(s):  
Trauma Center ◽  
Massive Transfusion ◽  
Massive Transfusion Protocol ◽  
Level 1 ◽  
Level 1 Trauma Center ◽  
Transfusion Protocol
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