Expression of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is required for virus growth and neoplastic transformation

Journal of General Virology ◽

10.1099/0022-1317-73-6-1417 ◽

1992 ◽

Vol 73 (6) ◽

pp. 1417-1428 ◽

Author(s):

C. C. Smith ◽

M. Kulka ◽

J. P. Wymer ◽

T. D. Chung ◽

L. Aurelian

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Ribonucleotide Reductase ◽

Herpes Simplex Virus Type ◽

Large Subunit ◽

Neoplastic Transformation ◽

Virus Growth ◽

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Leucine repeats in the large subunit of herpes simplex virus type 2 ribonucleotide reductase (RR; ICP10) are involved in RR activity and subunit complex formation

Journal of General Virology ◽

10.1099/0022-1317-72-5-1139 ◽

1991 ◽

Vol 72 (5) ◽

pp. 1139-1144 ◽

Author(s):

T. D. Chung ◽

J. Luo ◽

J. P. Wymer ◽

C. C. Smith ◽

L. Aurelian

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Complex Formation ◽

Ribonucleotide Reductase ◽

Herpes Simplex Virus Type ◽

Large Subunit ◽

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ATP and SH3 Binding Sites in the Protein Kinase of the Large Subunit of Herpes Simplex Virus Type 2 of Ribonucleotide Reductase (ICP10)

Journal of Biological Chemistry ◽

10.1074/jbc.271.29.17021 ◽

1996 ◽

Vol 271 (29) ◽

pp. 17021-17027 ◽

Author(s):

John W. Nelson ◽

Jia Zhu ◽

Cynthia C. Smith ◽

Michael Kulka ◽

Laure Aurelian

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Protein Kinase ◽

Ribonucleotide Reductase ◽

Herpes Simplex Virus Type ◽

Binding Sites ◽

Large Subunit ◽

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Immediate early and functional AP-1 cis-response elements are involved in the transcriptional regulation of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10)

Virus Research ◽

10.1016/0168-1702(92)90112-m ◽

1992 ◽

Vol 23 (3) ◽

pp. 253-270 ◽

Author(s):

James P. Wymer ◽

Colette M.J. Aprhys ◽

Theodore D. Chung ◽

Chu-Pei Feng ◽

Michael Kulka ◽

...

Keyword(s):

Transcriptional Regulation ◽

Herpes Simplex Virus ◽

Herpes Simplex ◽

Ribonucleotide Reductase ◽

Herpes Simplex Virus Type ◽

Large Subunit ◽

Response Elements ◽

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AP-1cis-Response Elements Are Involved in Basal Expression and Vmw110 Transactivation of the Large Subunit of Herpes Simplex Virus Type 2 Ribonucleotide Reductase (ICP10)

Virology ◽

10.1006/viro.1997.8522 ◽

1997 ◽

Vol 231 (2) ◽

pp. 301-312 ◽

Author(s):

Jia Zhu ◽

Laure Aurelian

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Ribonucleotide Reductase ◽

Herpes Simplex Virus Type ◽

Large Subunit ◽

Response Elements ◽

Basal Expression ◽

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Herpes simplex virus type 2 unique biological properties include neoplastic potential mediated by the Pk domain of the large subunit of ribonucleotide reductase

Frontiers in Bioscience ◽

10.2741/a238 ◽

1998 ◽

Vol 3 (4) ◽

pp. d237-249 ◽

Author(s):

Laure Aurelian

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Ribonucleotide Reductase ◽

Herpes Simplex Virus Type ◽

Large Subunit ◽

Biological Properties ◽

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Stress up-regulates neuronal expression of the herpes simplex virus type 2 large subunit of ribonucleotide reductase (R1; ICP10) by activating activator protein 1

Journal of NeuroVirology ◽

10.1080/13550280591002423 ◽

2005 ◽

Vol 11 (4) ◽

pp. 329-336 ◽

Author(s):

Michael D Gober ◽

Samantha Q Wales ◽

J Colin Hunter ◽

Bhuvnesh K Sharma ◽

Laure Aurelian

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Ribonucleotide Reductase ◽

Herpes Simplex Virus Type ◽

Large Subunit ◽

Activator Protein 1 ◽

Activator Protein ◽

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Identification of immediate-early-type cis-response elements in the promoter for the ribonucleotide reductase large subunit from herpes simplex virus type 2.

Journal of Virology ◽

10.1128/jvi.63.6.2773-2784.1989 ◽

1989 ◽

Vol 63 (6) ◽

pp. 2773-2784 ◽

Author(s):

J P Wymer ◽

T D Chung ◽

Y N Chang ◽

G S Hayward ◽

L Aurelian

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Ribonucleotide Reductase ◽

Herpes Simplex Virus Type ◽

Large Subunit ◽

Response Elements ◽

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Enhanced malignant transformation induced by expression of a distinct protein domain of ribonucleotide reductase large subunit from herpes simplex virus type 2.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.88.18.8257 ◽

1991 ◽

Vol 88 (18) ◽

pp. 8257-8261 ◽

Author(s):

M. A. Ali ◽

D. McWeeney ◽

A. Milosavljevic ◽

J. Jurka ◽

R. J. Jariwalla

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Malignant Transformation ◽

Ribonucleotide Reductase ◽

Herpes Simplex Virus Type ◽

Large Subunit ◽

Protein Domain ◽

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Papillomavirus Trans-activator Protein E2 Activates Expression from the Promoter for the Ribonucleotide Reductase Large Subunit from Herpes Simplex Virus Type 2

Journal of General Virology ◽

10.1099/0022-1317-71-8-1817 ◽

1990 ◽

Vol 71 (8) ◽

pp. 1817-1821 ◽

Author(s):

J. P. Wymer ◽

L. Aurelian

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Ribonucleotide Reductase ◽

Herpes Simplex Virus Type ◽

Large Subunit ◽

Activator Protein ◽

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Vaccine potential of a herpes simplex virus type 2 mutant deleted in the PK domain of the large subunit of ribonucleotide reductase (ICP10)

Vaccine ◽

10.1016/s0264-410x(98)00470-8 ◽

1999 ◽

Vol 17 (15-16) ◽

pp. 1951-1963 ◽

Author(s):

L Aurelian

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Ribonucleotide Reductase ◽

Herpes Simplex Virus Type ◽

Large Subunit ◽

Vaccine Potential ◽

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