scholarly journals Adaptive optics enhanced all-optical photoacoustic tomography

2021 ◽  
Author(s):  
Jakub Czuchnowski ◽  
Robert Prevedel
Keyword(s):  
High Resolution ◽  
Image Quality ◽  
Adaptive Optics ◽  
Photoacoustic Signal ◽  
Photoacoustic Tomography ◽  
Optical Aberrations ◽  
Fabry Perot ◽  
Mammalian Tissues ◽  
All Optical

AbstractAll-optical ultrasound detection bears a number of unique advantages for photoacoustic tomography, including the ability for high resolution sampling of the acoustic field and its compatibility with a wide variety of other optical modalities. However, optical schemes based on miniaturized cavities are sensitive to optical aberrations as well as manufacturing-induced cavity imperfections which degrade sensor sensitivity and deteriorate photoacoustic image quality. Here we present an experimental method based on adaptive optics that is capable of enhancing the overall sensitivity of Fabry-Pérot based photoacoustic sensors. We experimentally observe clear improvements in photoacoustic signal detection as well as overall image quality after photoacoustic tomography reconstructions when applied to mammalian tissues in vivo.

scholarly journals High-Resolution Adaptive Optics in Vivo Autofluorescence Imaging in Stargardt Disease

2019 ◽  
Vol 137 (6) ◽  
pp. 603 ◽  
Author(s):  
Hongxin Song ◽  
Ethan A. Rossi ◽  
Qiang Yang ◽  
Charles E. Granger ◽  
Lisa R. Latchney ◽  
...  
Keyword(s):  
High Resolution ◽  
Adaptive Optics ◽  
Autofluorescence Imaging ◽  
Stargardt Disease

scholarly journals Ultra-high resolution adaptive optics: optical coherence tomography for in vivo imaging of healthy and diseased retinal structures

2008 ◽  
Author(s):  
Robert J. Zawadzki ◽  
Yan Zhang ◽  
Steven M. Jones ◽  
Stacey S. Choi ◽  
Barry Cense ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Adaptive Optics ◽  
In Vivo Imaging ◽  
Optical Coherence

Adaptive optics - optical coherence tomography for in vivo retinal imaging: effects of spectral bandwidth on image quality

2006 ◽  
Author(s):  
Robert J. Zawadzki ◽  
Steven M. Jones ◽  
Mingtao Zhao ◽  
Stacey S. Choi ◽  
Sophie S. Laut ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Image Quality ◽  
Adaptive Optics ◽  
Retinal Imaging ◽  
Optical Coherence ◽  
Spectral Bandwidth

scholarly journals All-optical endoscopic probe for high resolution 3D photoacoustic tomography

2017 ◽  
Author(s):  
R. Ansari ◽  
E. Zhang ◽  
A. E. Desjardins ◽  
P. C. Beard
Keyword(s):  
High Resolution ◽  
Photoacoustic Tomography ◽  
All Optical

In vivo high-resolution fluorescence retinal imaging with adaptive optics

2006 ◽  
Author(s):  
Daniel C. Gray ◽  
William Merigan ◽  
Bernard P. Gee ◽  
Jessica I. Wolfing ◽  
Jason Porter ◽  
...  
Keyword(s):  
High Resolution ◽  
Adaptive Optics ◽  
Retinal Imaging

scholarly journals Statistical analysis of ocular monochromatic aberrations in Chinese population for adaptive optics ophthalmoscope design

2017 ◽  
Vol 10 (01) ◽  
pp. 1650038 ◽  
Author(s):  
Junlei Zhao ◽  
Fei Xiao ◽  
Jian Kang ◽  
Haoxin Zhao ◽  
Yun Dai ◽  
...  
Keyword(s):  
High Resolution ◽  
Adaptive Optics ◽  
Chinese Population ◽  
Imaging System ◽  
Retinal Imaging ◽  
Clinical Environment ◽  
Monochromatic Aberrations ◽  
Imaging System Design ◽  
Healthy Eyes

It is necessary to know the distribution of the Chinese eye’s aberrations in clinical environment to guide high-resolution retinal imaging system design for large Chinese population application. We collected the monochromatic wave aberration of 332 healthy eyes and 344 diseased eyes in Chinese population across a 6.0-mm pupil. The aberration statistics of Chinese eyes including healthy eyes and diseased eyes were analyzed, and some differences of aberrations between the Chinese and European race were concluded. On this basis, the requirement for adaptive optics (AO) correction of the Chinese eye’s monochromatic aberrations was analyzed. The result showed that a stroke of 20[Formula: see text][Formula: see text]m and ability to correct aberrations up to the 8th Zernike order were needed for reflective wavefront correctors to achieve near diffraction-limited imaging in both groups for a reference wavelength of 550[Formula: see text]nm and a pupil diameter of 6.0[Formula: see text]mm. To verify the analysis mentioned above, an AO flood-illumination system was established, and high-resolution retinal imaging in vivo was achieved for Chinese eye including both healthy and diseased eyes.

scholarly journals Adaptive-optics optical coherence tomography for high-resolution and high-speed 3D retinal in vivo imaging

2005 ◽  
Vol 13 (21) ◽  
pp. 8532 ◽  
Author(s):  
Robert J. Zawadzki ◽  
Steven M. Jones ◽  
Scot S. Olivier ◽  
Mingtao Zhao ◽  
Bradley A. Bower ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Adaptive Optics ◽  
In Vivo Imaging ◽  
High Speed ◽  
Optical Coherence
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