scholarly journals Holographic optical trapping Raman micro-spectroscopy of interacting live cells

2018 ◽  
Author(s):  
F. Sinjab ◽  
H. M. Elsheikha ◽  
D. Awuah ◽  
G. Gibson ◽  
M. Padgett ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Optical Tweezers ◽  
Optical Trapping ◽  
High Spectral Resolution ◽  
Live Cells ◽  
Light Modulator ◽  
Complex Interactions ◽  
Laser Trap ◽  
Confocal Raman ◽  
Interactive Manipulation

ABSTRACTWe present a combined holographic optical tweezers and confocal Raman spectroscopy instrument which allows fast, flexible, and interactive manipulation with molecular measurement of interacting live cell systems. Multiple laser foci created using a spatial light modulator are simultaneously used for optical trapping and spontaneous Raman spectroscopy. To enable confocal Raman measurements with high spectral resolution, a digital micro-mirror device was used to generate reflective pinholes which are matched to each laser trap. We demonstrate this unique capability by initiating complex interactions between multiple live cells whilst non-invasively acquiring Raman spectra of the processes with high spatial, spectral, and temporal resolution.

Dual wavelength optical tweezers for confocal Raman spectroscopy

2005 ◽  
Vol 245 (1-6) ◽  
pp. 465-470 ◽  
Author(s):  
C.M. Creely ◽  
G.P. Singh ◽  
D. Petrov
Keyword(s):  
Raman Spectroscopy ◽  
Optical Tweezers ◽  
Dual Wavelength ◽  
Confocal Raman Spectroscopy ◽  
Confocal Raman

Optical trapping of particles combined with confocal Raman spectroscopy in an optofluidic chip

2017 ◽  
Author(s):  
Heidi Ottevaere ◽  
Qing Liu ◽  
Diane de Coster ◽  
Jürgen Van Erps ◽  
Michael Vervaeke ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Optical Trapping ◽  
Confocal Raman Spectroscopy ◽  
Confocal Raman ◽  
Optofluidic Chip

Use of Confocal RAMAN Spectroscopy to Evaluate Penetration of Chemicals into the Cornea: Proof of Principle

2015 ◽  
Vol 238 (2) ◽  
pp. S326
Author(s):  
H. Rothe ◽  
B.D. Brandner ◽  
L. Ringstad ◽  
P. McNamee
Keyword(s):  
Raman Spectroscopy ◽  
Confocal Raman Spectroscopy ◽  
Confocal Raman ◽  
Proof Of Principle

scholarly journals Single-cell discrimination based on optical tweezers Raman spectroscopy

2013 ◽  
Vol 58 (21) ◽  
pp. 2594-2600 ◽  
Author(s):  
HongFei Ma ◽  
Yong Zhang ◽  
AnPei Ye
Keyword(s):  
Raman Spectroscopy ◽  
Single Cell ◽  
Optical Tweezers ◽  
Cell Discrimination

Non-invasive analysis of hormonal variations and effect of postmenopausal Vagifem treatment on women using in vivo high wavenumber confocal Raman spectroscopy

The Analyst ◽  
2013 ◽  
Vol 138 (14) ◽  
pp. 4120 ◽  
Author(s):  
Shiyamala Duraipandian ◽  
Wei Zheng ◽  
Joseph Ng ◽  
Jeffrey J. H. Low ◽  
A. Ilancheran ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Confocal Raman Spectroscopy ◽  
Non Invasive ◽  
Confocal Raman

scholarly journals Effect of Ionic Liquids on the Physical Properties of the Newly Synthesized Conducting Polymer

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Dong Uk Lee ◽  
Jin Yeong Jeong ◽  
Ji Woong Han ◽  
Gi-Chung Kwon ◽  
Pankaj Attri ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Ionic Liquids ◽  
Conducting Polymer ◽  
Optical Devices ◽  
Polymer Mixtures ◽  
Confocal Raman Spectroscopy ◽  
Vis Spectroscopy ◽  
Film Roughness ◽  
Confocal Raman ◽  
Insight Into

Conducting polymer has many applications in electronics, optical devices, sensors, and so on; however, there is still a massive scope of improvement in this area. Therefore, towards this aim, in this study, we synthesized a new thiophene-based conducting polymer, 2-heptadecyl-5-hexyl-6-(5-methylthiophen-2-yl)-4-(5-((E)-prop-1-enyl)thiophen-2-yl)-5H-pyrrolo[3,4-d]thiazole (HHMPT). Further, to increase its application, the interactions between the conducting polymer (HHMPT) and ionic liquids (ILs) were investigated by UV-Vis spectroscopy, FTIR spectroscopy, and confocal Raman spectroscopy techniques. Moreover, film roughness and conductivity of the polymer film with or without ILs were also studied. The imidazolium- and ammonium family ILs with the potential to interact with the newly synthesized conducting polymer were used. The results of the interaction studies revealed that the imidazolium family IL-polymer mixtures and ammonium family IL-polymer mixtures have almost similar conductivity at low concentration of ILs. This study provides an insight into the combined effect of a polymer and ILs and may generate many theoretical and experimental opportunities.

The Potential Applications of Raman Spectroscopy in Unravelling Complex Palaeowildfire Ecosystems

2021 ◽  
Author(s):  
Thomas Theurer ◽  
David Muirhead ◽  
David Jolley ◽  
Dmitri Mauquoy
Keyword(s):  
Raman Spectroscopy ◽  
Carbonaceous Material ◽  
Complex Interactions ◽  
Intensity Changes ◽  
Potential Applications ◽  
Ecosystem Studies ◽  
History Of ◽  
The Impact ◽  
Unique Relationship

<p>Raman spectroscopy represents a novel methodology of characterising plant-fire interactions through geological history, with enormous potential. Applications of Raman spectroscopy to charcoal have shown that this is an effective method of understanding intensity changes across palaeofire regimes. Such analyses have relied on the determination of appropriate Raman parameters, given their relationship with temperature of formation and microstructural changes in reference charcoals. Quantitative assessments of charcoal microstructure have also been successfully applied to the assessment of carbonaceous maturation under alternate thermal regimes, such as pyroclastic volcanism. Palaeowildfire systems in association with volcanism may present a complex history of thermal maturation, given interactions between detrital charcoals and volcanogenic deposition. However, whilst palaeofire and volcanic maturation of carbonaceous material are well understood individually, their interaction has yet to be characterised. Here we present the first analysis of palaeofire charcoals derived from volcanic ignition utilising Raman spectroscopy. Our results indicate that complex interactions between volcanism and palaeofire systems may be better understood by the characterisation of charcoal microstructure, alongside palaeobotanical and ecosystem studies. Understanding the unique relationship between wildfires and volcanism, and the impact that this has on the fossil record, may better assist our understanding of wildfire systems in deep history. Further still, this highlights the potential for better understanding the socioecological impacts of modern and future wildfire systems closely associated with volcanic centres. </p>

A Portable Ultrawideband Confocal Raman Spectroscopy System with a Handheld Probe for Skin Studies

ACS Sensors ◽  
2021 ◽  
Author(s):  
Ruochong Zhang ◽  
Renzhe Bi ◽  
Chris Ho Jun Hui ◽  
Poongkulali Rajarahm ◽  
U.S. Dinish ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Confocal Raman Spectroscopy ◽  
Spectroscopy System ◽  
Confocal Raman
Sign in / Sign up

Export Citation Format

Share Document