Extended field-of-view ultrathin microendoscopes with built-in aberration correction for high-resolution imaging with minimal invasiveness
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We present a novel approach to correct optical aberrations in ultrathin gradient-index rod lens-based endoscopes using microfabricated aspherical lenses. Corrected microendoscopes have up to 9 folds larger field-of-view compared to uncorrected probes. Using extended field-of-view (eFOV) microendoscopes, we report two-photon imaging of GCaMP6 signals in the mouse hippocampus in vivo with unprecedented combination of high spatiotemporal resolution and minimal invasiveness.
2003 ◽
Vol 35
(Supplement 1)
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pp. S266
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2010 ◽
Vol 109
(6)
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pp. 1974-1979
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2017 ◽
Vol 63
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pp. 179-185
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2020 ◽
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2016 ◽
Vol 49
(9)
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pp. 1948-1952
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Keyword(s):
2020 ◽
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