scholarly journals Nephrogenic systemic fibrosis (NSF): a late adverse reaction to some of the gadolinium based contrast agents

2007 ◽  
Vol 7 (1) ◽  
pp. 130-137 ◽  
Author(s):  
Henrik S. Thomsen
Keyword(s):  
Adverse Reaction ◽  
Contrast Agents ◽  
Nephrogenic Systemic Fibrosis ◽  
Late Adverse Reaction

Gadolinium-based MR Contrast Agents and Nephrogenic Systemic Fibrosis

Radiology ◽  
2007 ◽  
Vol 242 (3) ◽  
pp. 647-649 ◽  
Author(s):  
Phillip H. Kuo ◽  
Emanuel Kanal ◽  
Ali K. Abu-Alfa ◽  
Shawn E. Cowper
Keyword(s):  
Contrast Agents ◽  
Nephrogenic Systemic Fibrosis ◽  
Mr Contrast Agents

scholarly journals Nephrogenic systemic fibrosis (NSF) and gadolinium-based contrast media

2013 ◽  
Vol 17 (3) ◽  
pp. 106-107
Author(s):  
P.S. Ngoya ◽  
Z Vawda ◽  
J.W Lotz
Keyword(s):  
Renal Failure ◽  
Contrast Media ◽  
Contrast Agents ◽  
Nephrogenic Systemic Fibrosis ◽  
Overwhelming Majority ◽  
Tissue Fibrosis ◽  
Systemic Disorder ◽  
High Doses

Nephrogenic systemic fibrosis (NSF), unknown before March 1997 and first described in 2000, is a systemic disorder characterised by widespread tissue fibrosis. The first known case occurred in 1997, after the use of gadolinium-based contrast agents (GBCAs) at high doses in patients with renal failure had become routine. An overwhelming majority occurred within weeks to months after injection of a GBCA. This note comprises guidelines on the prevention of NSF.

scholarly journals Non-uremic Calciphylaxis: A Rare and Late Adverse Reaction of Warfarin

2019 ◽  
Vol 14 (3) ◽  
pp. 246-248 ◽  
Author(s):  
Dhruvkumar M. Patel ◽  
Mukundkumar V. Patel ◽  
Akash D. Patel ◽  
Jignesh C. Kaklotar ◽  
Greshaben R. Patel ◽  
...  
Keyword(s):  
Adverse Reaction ◽  
Inflammatory Markers ◽  
Metabolic Profile ◽  
Connective Tissue Diseases ◽  
Skin Ulcer ◽  
Wound Treatment ◽  
History Of ◽  
The Right ◽  
Work Up ◽  
Late Adverse Reaction

Background:Calciphylaxis is a complex dermatological lesion of micro vascular calcification that is typically presented as panniculitis with gangrenous painful lesions having uremic and non-uremic causes.Case Report:We present a case of a 48-year old male with a history of paroxysmal atrial fibrillation and hypertension taking amlodipine 5 mg and warfarin 5 mg daily for the last 26 months. The patient had a 6- months history of painful swelling followed by necrotic skin ulcer over the right leg. His remarkable examination findings were right leg tender ulcer with surrounding erythema and secondary sepsis. His hemogram, metabolic profile and connective tissue diseases work up were unremarkable except leucocytosis and raised inflammatory markers. His local part radiological and skin biopsy findings were suggestive of calciphylaxis.Results and Conclusion:In our case, warfarin and amlodipine were culprit drugs for the lesion, but Naranjo score (warfarin 7and amlodipine 1) speculate warfarin as a probable adverse reaction of warfarin. The lesion was cured with local wound treatment after discontinuation of warfarin. The physician should be aware of this rare cutaneous disorder of systemic origin for proper management.

scholarly journals Subsequent MRI of pediatric patients after an adverse reaction to Gadolinium-based contrast agents

PLoS ONE ◽  
2020 ◽  
Vol 15 (4) ◽  
pp. e0230781 ◽  
Author(s):  
Azadeh Hojreh ◽  
Andreas Peyrl ◽  
Aleksandra Bundalo ◽  
Zsolt Szepfalusi
Keyword(s):  
Adverse Reaction ◽  
Contrast Agents ◽  
Pediatric Patients

scholarly journals Risk of nephrogenic systemic fibrosis is low in patients with chronic liver disease exposed to gadolinium-based contrast agents

2014 ◽  
Vol 41 (5) ◽  
pp. 1259-1267 ◽  
Author(s):  
Emmanuil Smorodinsky ◽  
David S. Ansdell ◽  
Zeke W. Foster ◽  
Sameer M. Mazhar ◽  
Irene Cruite ◽  
...  
Keyword(s):  
Liver Disease ◽  
Contrast Agents ◽  
Chronic Liver Disease ◽  
Nephrogenic Systemic Fibrosis ◽  
Chronic Liver
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