The application of the integrals of the motion of a quantum system in deriving Green function or propagator is established. The Greenfunction is shown to be the eigenfunction of the integrals of the motion which described initial points of the system trajectory in the phasespace. The explicit expressions for the Green functions of the damped harmonic oscillator, the harmonic oscillator with strongly pulsatingmass, and the harmonic oscillator with mass growing with time are obtained in co-ordinate representations. The connection between theintegrals of the motion method and other method such as Feynman path integral and Schwinger method are also discussed.