scholarly journals X-ray crystal structures of the influenza A M2 proton channel bound to amantadine, rimantadine and inhibiting compounds

2017 ◽  
Vol 73 (a1) ◽  
pp. a78-a78
Author(s):  
Jessica L. Thomaston ◽  
William F. DeGrado
Keyword(s):  
Crystal Structures ◽  
Influenza A ◽  
Proton Channel ◽  
X Ray ◽  
M2 Proton Channel

scholarly journals X-ray Crystal Structures of the Influenza M2 Proton Channel Drug-Resistant V27A Mutant Bound to a Spiro-Adamantyl Amine Inhibitor Reveal the Mechanism of Adamantane Resistance

Biochemistry ◽  
2020 ◽  
Vol 59 (4) ◽  
pp. 627-634 ◽  
Author(s):  
Jessica L. Thomaston ◽  
Athina Konstantinidi ◽  
Lijun Liu ◽  
George Lambrinidis ◽  
Jingquan Tan ◽  
...  
Keyword(s):  
Crystal Structures ◽  
Proton Channel ◽  
Drug Resistant ◽  
X Ray ◽  
M2 Proton Channel

scholarly journals X-ray Crystal Structure of the Influenza A M2 Proton Channel S31N Mutant in Two Conformational States: An Open and Shut Case

2019 ◽  
Vol 141 (29) ◽  
pp. 11481-11488 ◽  
Author(s):  
Jessica L. Thomaston ◽  
Yibing Wu ◽  
Nicholas Polizzi ◽  
Lijun Liu ◽  
Jun Wang ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Influenza A ◽  
Proton Channel ◽  
Conformational States ◽  
X Ray ◽  
M2 Proton Channel

scholarly journals Functional, Dynamic and Structural Understanding of M2 Proton Channel from Influenza A and its Inhibition

2016 ◽  
Vol 110 (3) ◽  
pp. 192a
Author(s):  
Timothy A. Cross ◽  
Riqiang Fu ◽  
E. Vindana Ekanayake ◽  
Yimin Miao ◽  
Joana Paulino ◽  
...  
Keyword(s):  
Influenza A ◽  
Proton Channel ◽  
M2 Proton Channel

scholarly journals pH Titration and Acid Activation of the Full-Length Influenza a M2 Proton Channel in Lipid Bilayers

2015 ◽  
Vol 108 (2) ◽  
pp. 246a
Author(s):  
Yimin Miao ◽  
Riqiang Fu ◽  
Huan-Xiang Zhou ◽  
Huajun Qin ◽  
Timothy A. Cross
Keyword(s):  
Lipid Bilayers ◽  
Influenza A ◽  
Full Length ◽  
Proton Channel ◽  
Acid Activation ◽  
Ph Titration ◽  
M2 Proton Channel

scholarly journals Channel activity of mirror-image M2 proton channel of influenza A virus is blocked by achiral or chiral inhibitors

2018 ◽  
Vol 10 (3) ◽  
pp. 211-216 ◽  
Author(s):  
Qing-Yan Guo ◽  
Long-Hua Zhang ◽  
Chao Zuo ◽  
Dong-Liang Huang ◽  
Zhipeng A. Wang ◽  
...  
Keyword(s):  
Influenza A Virus ◽  
Influenza A ◽  
Mirror Image ◽  
Proton Channel ◽  
Channel Activity ◽  
M2 Proton Channel

scholarly journals Asp44 Stabilizes the Trp41 Gate of the M2 Proton Channel of Influenza A Virus

Structure ◽  
2013 ◽  
Vol 21 (11) ◽  
pp. 2033-2041 ◽  
Author(s):  
Chunlong Ma ◽  
Giacomo Fiorin ◽  
Vincenzo Carnevale ◽  
Jun Wang ◽  
Robert A. Lamb ◽  
...  
Keyword(s):  
Influenza A Virus ◽  
Influenza A ◽  
Proton Channel ◽  
M2 Proton Channel
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