Crystallography of the integral membrane protein EmrE fromEscherichia coli

2004 ◽  
Vol 60 (12) ◽  
pp. 2399-2402 ◽  
Author(s):  
Che Ma ◽  
Geoffrey Chang
Keyword(s):  
Membrane Protein ◽  
Integral Membrane Protein ◽  
Fromescherichia Coli

Crystallization and preliminary X-ray analysis of ferric enterobactin receptor FepA, an integral membrane protein fromEscherichia coli

1998 ◽  
Vol 54 (4) ◽  
pp. 697-699 ◽  
Author(s):  
Barbara S. Smith ◽  
Bostjan Kobe ◽  
Ravi Kurumbail ◽  
Susan K. Buchanan ◽  
Lalitha Venkatramani ◽  
...  
Keyword(s):  
Membrane Protein ◽  
Integral Membrane Protein ◽  
X Ray ◽  
Fromescherichia Coli

scholarly journals Solution NMR Structure and Functional Analysis of the Integral Membrane Protein YgaP fromEscherichia coli

2014 ◽  
Vol 289 (34) ◽  
pp. 23482-23503 ◽  
Author(s):  
Cédric Eichmann ◽  
Christos Tzitzilonis ◽  
Enrica Bordignon ◽  
Innokentiy Maslennikov ◽  
Senyon Choe ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Membrane Protein ◽  
Integral Membrane Protein ◽  
Nmr Structure ◽  
Solution Nmr ◽  
Fromescherichia Coli

Purification, crystallization and preliminary crystallographic studies of an integral membrane protein, cytochromebo3ubiquinol oxidase fromEscherichia coli

2000 ◽  
Vol 56 (8) ◽  
pp. 1076-1078 ◽  
Author(s):  
Jeff Abramson ◽  
Gisela Larsson ◽  
Bernadette Byrne ◽  
Anne Puustinen ◽  
Arturo Garcia-Horsman ◽  
...  
Keyword(s):  
Membrane Protein ◽  
Integral Membrane Protein ◽  
Fromescherichia Coli

scholarly journals Predicting the Structure and Dynamics of Membrane Protein GerAB from Bacillus subtilis

2021 ◽  
Vol 22 (7) ◽  
pp. 3793
Author(s):  
Sophie Blinker ◽  
Jocelyne Vreede ◽  
Peter Setlow ◽  
Stanley Brul
Keyword(s):  
Bacillus Subtilis ◽  
Membrane Protein ◽  
Spore Germination ◽  
Structural Information ◽  
Transmembrane Protein ◽  
Homology Modelling ◽  
Water Channel ◽  
Md Simulations ◽  
Integral Membrane Protein ◽  
Starting Point

Bacillus subtilis forms dormant spores upon nutrient depletion. Germinant receptors (GRs) in spore’s inner membrane respond to ligands such as L-alanine, and trigger spore germination. In B. subtilis spores, GerA is the major GR, and has three subunits, GerAA, GerAB, and GerAC. L-Alanine activation of GerA requires all three subunits, but which binds L-alanine is unknown. To date, how GRs trigger germination is unknown, in particular due to lack of detailed structural information about B subunits. Using homology modelling with molecular dynamics (MD) simulations, we present structural predictions for the integral membrane protein GerAB. These predictions indicate that GerAB is an α-helical transmembrane protein containing a water channel. The MD simulations with free L-alanine show that alanine binds transiently to specific sites on GerAB. These results provide a starting point for unraveling the mechanism of L-alanine mediated signaling by GerAB, which may facilitate early events in spore germination.

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