Automating the application of smart materials for protein crystallization
2015 ◽
Vol 71
(3)
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pp. 534-540
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Keyword(s):
The fabrication and validation of the first semi-liquid nonprotein nucleating agent to be administered automatically to crystallization trials is reported. This research builds upon prior demonstration of the suitability of molecularly imprinted polymers (MIPs; known as `smart materials') for inducing protein crystal growth. Modified MIPs of altered texture suitable for high-throughput trials are demonstrated to improve crystal quality and to increase the probability of success when screening for suitable crystallization conditions. The application of these materials is simple, time-efficient and will provide a potent tool for structural biologists embarking on crystallization trials.
2011 ◽
Vol 108
(27)
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pp. 11081-11086
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2011 ◽
Vol 108
(45)
◽
pp. 18566-18566
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2015 ◽
Vol 135
(8)
◽
pp. 305-310
2020 ◽
Vol 12
(sp1)
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2013 ◽
Vol 40
(7)
◽
pp. 1071-1075
2010 ◽
Vol 38
(3)
◽
pp. 401-404