Effects of preload, after-load and myocardial contractility on pressure-volume loop of the cardiovascular system model

2015 ◽  
Author(s):  
Yonghua Lao ◽  
Hongke Ji ◽  
Yuming Huang ◽  
Junwei Liang ◽  
Yueshan Huang ◽  
...  
Keyword(s):  
Cardiovascular System ◽  
Myocardial Contractility ◽  
System Model ◽  
Cardiovascular System Model

scholarly journals Structural identifiability analysis of a cardiovascular system model

2016 ◽  
Vol 38 (5) ◽  
pp. 433-441 ◽  
Author(s):  
Antoine Pironet ◽  
Pierre C. Dauby ◽  
J. Geoffrey Chase ◽  
Paul D. Docherty ◽  
James A. Revie ◽  
...  
Keyword(s):  
Cardiovascular System ◽  
System Model ◽  
Structural Identifiability ◽  
Identifiability Analysis ◽  
Cardiovascular System Model ◽  
Structural Identifiability Analysis

scholarly journals Cardiovascular System Model-Based Phenotyping of Heart Failure with Preserved Ejection Fraction

2019 ◽  
Vol 25 (8) ◽  
pp. S33
Author(s):  
Edith Jones ◽  
David M. Cameron ◽  
Daniel A. Beard ◽  
Scott L. Hummel ◽  
Brian E. Carlson
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Cardiovascular System ◽  
System Model ◽  
Preserved Ejection Fraction ◽  
Model Based ◽  
Cardiovascular System Model

scholarly journals Simulating transient ventricular interaction using a minimal cardiovascular system model

2006 ◽  
Vol 27 (2) ◽  
pp. 165-179 ◽  
Author(s):  
Bram W Smith ◽  
J Geoffrey Chase ◽  
Geoff M Shaw ◽  
Roger I Nokes
Keyword(s):  
Cardiovascular System ◽  
System Model ◽  
Ventricular Interaction ◽  
Cardiovascular System Model

scholarly journals Experimentally verified minimal cardiovascular system model for rapid diagnostic assistance

2005 ◽  
Vol 13 (9) ◽  
pp. 1183-1193 ◽  
Author(s):  
Bram W. Smith ◽  
J. Geoffrey Chase ◽  
Geoffrey M. Shaw ◽  
Roger I. Nokes
Keyword(s):  
Cardiovascular System ◽  
System Model ◽  
Cardiovascular System Model

scholarly journals Practical identifiability analysis of a minimal cardiovascular system model

2019 ◽  
Vol 171 ◽  
pp. 53-65 ◽  
Author(s):  
Antoine Pironet ◽  
Paul D. Docherty ◽  
Pierre C. Dauby ◽  
J. Geoffrey Chase ◽  
Thomas Desaive
Keyword(s):  
Cardiovascular System ◽  
System Model ◽  
Identifiability Analysis ◽  
Practical Identifiability ◽  
Cardiovascular System Model

EQUILIBRIUM MULTIPLICITY IN A CARDIOVASCULAR SYSTEM MODEL

2006 ◽  
Vol 14 (03) ◽  
pp. 445-461 ◽  
Author(s):  
JOSE ALVAREZ-RAMIREZ ◽  
EDUARDO RODRIGUEZ ◽  
JUAN CARLOS ECHEVERRIA ◽  
JORGE X. VELASCO-HERNANDEZ
Keyword(s):  
Stroke Volume ◽  
Cardiovascular System ◽  
Equilibrium Points ◽  
Venous Pressure ◽  
Feedback Mechanism ◽  
System Model ◽  
Trivial Equilibrium ◽  
Cardiovascular System Model ◽  
Reliability And Robustness ◽  
Pressure Changes

The aim of this paper is to show that, for some parameters, a two-dimensional cardiovascular system model can exhibit intrinsic equilibrium multiplicity generated by a backward bifurcation, regardless of the baroreflex effect. The model considers the dynamics of arterial and venous compartments and a feedback effect in the stroke volume induced by venous pressure changes. The results of the mathematical analysis indicate that multiple non-trivial equilibrium points exist when the stroke volume function is convex around the origin. Interestingly, this equilibrium point structure would imply that under certain stroke volume functions, the baroreflex system would have to stabilize and regulate an unstable operating condition produced by certain values of the stroke volume. The paper ends with the discussion of some implications for the reliability and robustness of the baroreflex-feedback mechanism.

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