Pyrrole Plasma Polymer-Coated Fibrillar Scaffold Implant: Pilot Study in Rat Spinal Cord Transection with MRI

2021 ◽  
Author(s):  
Diana M. Osorio-Londono ◽  
Gloria S. Sanchez-Morales ◽  
Gustavo Garcia-Garcia ◽  
Axayacatl Morales-Guadarrama ◽  
Roberto Olayo-Gonzalez
Keyword(s):  
Spinal Cord ◽  
Pilot Study ◽  
Spinal Cord Transection ◽  
Plasma Polymer ◽  
Rat Spinal Cord

Regional blood flow in transected rat spinal cord during hypothermia

1990 ◽  
Vol 259 (6) ◽  
pp. H1649-H1654
Author(s):  
T. Sakamoto ◽  
A. Iwai ◽  
W. W. Monafo
Keyword(s):  
Spinal Cord ◽  
Blood Flow ◽  
Sciatic Nerve ◽  
Rectal Temperature ◽  
Regional Blood Flow ◽  
Spinal Cord Transection ◽  
The Other ◽  
Rat Spinal Cord ◽  
Caudal Spinal Cord

Regional blood flow (RBF) increases in the spinal cord and sciatic nerve of acutely hypothermic rats. To determine whether cord transection affects this response, we measured RBF in rat spinal cord and sciatic nerve 2 h after cord transection at vertebrae T8 (n = 18 rats) and T11 (n = 18 rats) using [14C]butanol distribution. Nine in each group were normothermic controls. In T11 transection-hypothermia (25-27 degrees C rectal temperature), RBF increased in the three rostral cord segments by 28-40% (P less than 0.05); caudally, cord RBF was depressed in two segments (P less than 0.05), unchanged in the other; RBF fell in nerve (P less than 0.05). In T8 transection-hypothermia, RBF was unchanged in the two rostral cord segments; caudally, RBF was depressed in one cord segment (P less than 0.05) and unchanged in the others; RBF was unchanged in nerve. We conclude that RBF does not rise in caudal spinal cord segments or in sciatic nerve during hypothermia in rats with prior spinal cord transection.

scholarly journals Complete rat spinal cord transection as a faithful model of spinal cord injury for translational cell transplantation

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Dunja Lukovic ◽  
Victoria Moreno-Manzano ◽  
Eric Lopez-Mocholi ◽  
Francisco Javier Rodriguez-Jiménez ◽  
Pavla Jendelova ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Cell Transplantation ◽  
Spinal Cord Transection ◽  
Rat Spinal Cord ◽  
Cord Injury

scholarly journals Noradrenergic innervation of the rat spinal cord caudal to a complete spinal cord transection: Effects of olfactory ensheathing glia

2010 ◽  
Vol 222 (1) ◽  
pp. 59-69 ◽  
Author(s):  
Aya Takeoka ◽  
Marc D. Kubasak ◽  
Hui Zhong ◽  
Jennifer Kaplan ◽  
Roland R. Roy ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Transection ◽  
Rat Spinal Cord ◽  
Noradrenergic Innervation ◽  
Olfactory Ensheathing Glia

The integration of NSC-derived and host neural networks after rat spinal cord transection

Biomaterials ◽  
2013 ◽  
Vol 34 (12) ◽  
pp. 2888-2901 ◽  
Author(s):  
Bi-Qin Lai ◽  
Jun-Mei Wang ◽  
Jing-Jing Duan ◽  
Yuan-Feng Chen ◽  
Huai-Yu Gu ◽  
...  
Keyword(s):  
Neural Networks ◽  
Spinal Cord ◽  
Spinal Cord Transection ◽  
Rat Spinal Cord

Integration of donor mesenchymal stem cell-derived neuron-like cells into host neural network after rat spinal cord transection

Biomaterials ◽  
2015 ◽  
Vol 53 ◽  
pp. 184-201 ◽  
Author(s):  
Xiang Zeng ◽  
Xue-Cheng Qiu ◽  
Yuan-Huan Ma ◽  
Jing-Jing Duan ◽  
Yuan-Feng Chen ◽  
...  
Keyword(s):  
Neural Network ◽  
Spinal Cord ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Spinal Cord Transection ◽  
Rat Spinal Cord

scholarly journals Graft of a Tissue-Engineered Neural Scaffold Serves as a Promising Strategy to Restore Myelination after Rat Spinal Cord Transection

2014 ◽  
Vol 23 (8) ◽  
pp. 910-921 ◽  
Author(s):  
Bi-Qin Lai ◽  
Jun-Mei Wang ◽  
Eng-Ang Ling ◽  
Jin-Lang Wu ◽  
Yuan-Shan Zeng
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Transection ◽  
Rat Spinal Cord ◽  
Promising Strategy

Implantation of a functional TEMPO-hydrogel induces recovery from rat spinal cord transection through promoting nerve regeneration and protecting bladder tissue

2020 ◽  
Vol 8 (6) ◽  
pp. 1695-1701 ◽  
Author(s):  
Yu Zhang ◽  
Liming Li ◽  
Jiafu Mu ◽  
Jiachen Chen ◽  
Shiqing Feng ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Nerve Regeneration ◽  
Nerve Repair ◽  
Spinal Cord Transection ◽  
Rat Spinal Cord ◽  
Bladder Tissue ◽  
Cord Injury

A novel TEMPO-immobilized hyaluronic hydrogel is fabricated to promote nerve repair through mitigating the oxidant microenvironment of spinal cord injury.

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