An intelligent monitoring and control system for highway daily maintenance is described in this paper. To manage maintenance machinery and operators more effectively, geographical information system (GIS), global positioning system (GPS), and wireless communication technologies are applied to the system which consists of three subsystems, detection and maintenance sequence planning system, detection and maintenance monitoring system, and PDA execution system. Maintenance machinery sequence planning system generates routes and schedules for maintenance machinery using GIS and optimization techniques. Maintenance machinery monitoring system monitors current positions of machinery and actual maintenance results as compared with planned sequences, routes and visit times, while PDA execution system transmits information for machinery positions and actual maintenance results using GPS and wireless communication technologies. The intelligent monitoring and control system can promote operation efficiency and reduce maintenance costs.