Medical segmentation is the primary task performed to diagnosis the abnormalities in the human body. The brain is the complex organ and anatomical segmentation of brain tissues is a challenging task. In this paper, we used Enhanced Independent component analysis to perform the segmentation of gray matter. We used modified K means, Expected Maximization and Hidden Markov random field to provide better spatial correlation that overcomes in-homogeneity, noise and low contrast. Our objective is achieved in two steps (i) initially unwanted tissues are clipped from the MRI image using skull stripped Algorithm (ii) Enhanced Independent Component analysis is used to perform the segmentation of gray matter. We apply the proposed method on both T1w and T2w MRI to perform segmentation of gray matter at different noisy environments. We evaluate the the performance of our proposed system with Jaccard Index, Dice Coefficient and Accuracy. We further compared the proposed system performance with the existing frameworks. Our proposed method gives better segmentation of gray matter useful for diagnosis neurodegenerative disorders.
Identifying brain networks in synaptic density PET (11C-UCB-J) with independent component analysis