scholarly journals Correction of the Cutaneous Manifestations of Essential Fatty Acid Deficiency in Man by Application of Sunflower-Seed Oil to the Skin

1975 ◽  
Vol 64 (4) ◽  
pp. 228-234 ◽  
Author(s):  
Colin Prottey ◽  
Peter J Hartop ◽  
Martin Press
Keyword(s):  
Fatty Acid ◽  
Essential Fatty Acid ◽  
Essential Fatty Acid Deficiency ◽  
Sunflower Seed ◽  
Seed Oil ◽  
Cutaneous Manifestations ◽  
Sunflower Seed Oil ◽  
Acid Deficiency ◽  
Fatty Acid Deficiency

Correction of Essential Fatty Acid Deficiency in Newborn Infants by Cutaneous Application of Sunflower-Seed Oil

PEDIATRICS ◽  
1976 ◽  
Vol 58 (5) ◽  
pp. 650-654
Author(s):  
Zvi Friedman ◽  
Stephen J. Shochat ◽  
M. Jeffrey Maisels ◽  
Keith H. Marks ◽  
Edward L. Lamberth
Keyword(s):  
Fatty Acid ◽  
Essential Fatty Acid ◽  
Sunflower Seed ◽  
Seed Oil ◽  
Newborn Infants ◽  
Eicosatrienoic Acid ◽  
Sunflower Seed Oil ◽  
Fatty Acid Deficiency ◽  
Cutaneous Application

Two newborn infants receiving long-term, fat-free parenteral nutrition developed essential fatty acid (EFA) deficiency. Biochemical evidence of EFA deficiency was documented in plasma, red blood cells, and adipose tissue and included a decrease in arachidonic and linoleic acids, an increase in 5,8,11-eicosatrienoic acid, palmitoleic and oleic acids and a trienoic/tetraenoic ratio of more than 0.4. Cutaneous application of sunflower-seed oil, a source rich in the essential fat linoleic acid, rapidly reversed the clinical and biochemical manifestations of deficiency in plasma.

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