scholarly journals Glycemic Control and Risk Factors for In‐Hospital Mortality and Vascular Complications after Coronary Artery Bypass Grafting in Patients with and without Preexisting Diabetes

2020 ◽  
Author(s):  
Yanyan Chen ◽  
Heng Zhang ◽  
Xiaopei Hou ◽  
Xiaojue Li ◽  
Xin Qian ◽  
...  
2011 ◽  
Vol 14 (2) ◽  
pp. 81 ◽  
Author(s):  
Scot C. Schultz ◽  
Scott Woodward ◽  
George Ebra

Background: At a time when cost containment in health care is under increased scrutiny, coronary artery bypass grafting remains the most widely performed cardiac surgical procedure in the world. This study compares 30-day mortality, morbidity, and resource use for off-pump coronary artery bypass (OPCAB) versus conventional coronary artery bypass (CCAB) revascularization.Methods: From January 2000 through December 2008, 1003 patients underwent OPCAB grafting by a single surgeon (S.C.S.). Data were prospectively collected, entered into a Society of Thoracic Surgeons adult cardiac surgery database, and analyzed retrospectively. We used propensity-matching techniques to match this cohort to a group of 1003 patients who underwent CCAB.Results: The hospital mortality rate was lower for the OPCAB patients than for the CCAB patients: 2.0% (20/1003) versus 2.8% (28/1003). Predictors of hospital mortality for the entire cohort included age (P = .001), cardiogenic shock (P = .001), congestive heart failure (P = .019), history of myocardial infarction (P = .001), and reoperation (P = .007). The overall incidence of morbidity was lower for the OPCAB patients (reoperation for bleeding, P = .011; prolonged ventilation, P = .035; stroke, P = .045; cardiac arrest, P = .004). OPCAB patients experienced significantly reduced procedure times (P = .001), postoperative ventilation times (P = .035), post-operative lengths of stay (P = .035), and blood product use (intraoperative, P = .001; postoperative, P = .001).Conclusion: These outcomes clearly demonstrate that OPCAB is a safe and effective procedure for myocardial revascularization. This retrospective, nonrandomized observational study has shown that the patients who underwent OPCAB had reduced morbidity and mortality, as well as decreased resource use, compared with those who underwent CCAB.


Renal Failure ◽  
2007 ◽  
Vol 29 (7) ◽  
pp. 823-828 ◽  
Author(s):  
Beril Akman ◽  
Ayse Bilgic ◽  
Gulsah Sasak ◽  
Siren Sezer ◽  
Atilla Sezgin ◽  
...  

Author(s):  
Iuliia Kareva ◽  
Vidadiue Efendiev ◽  
Alexey Nesmachnyy ◽  
Sardor Rakhmonov ◽  
Alexander Chernyavskiy ◽  
...  

Background and Aim: We aimed to identify risk factors for recurrent mitral regurgitation in two surgical treatment groups: isolated coronary artery bypass grafting (CABG) and CABG combined with mitral valve (MV) repair in patients with moderate ischemic mitral regurgitation (IMR). Methods: A single-centre, prospective, randomised study, which included 76 patients with ICM and moderate mitral regurgitation (MR). Study included two groups: isolated CABG and CABG with MV repair (MVR). Isolated annuloplasty was used to correct mitral insufficiency in the CABG + MVR group. Results: Isolated CABG or CABG combined with MVR in patients with ICM does not lead to a statistically significant decreasing of MR in the long-term period compared to baseline values. However, in one year after surgery, the degree of MR after combined surgery is lower than the initial values. The identification of predictors of the progression of IMR in ICM made it possible to determine the threshold values for the effectiveness of MVR, and the assessment of echocardiographic predictors for annuloplasty helps to choose the right surgical tactic of patients. Conclusions: Coronary revascularization with surgical of IMR in patients with ICM does not increase the number of complications in the early postoperative period compared to the group of isolated CABG. In patients with ICM and moderate MR after isolated CABG, the progression of MR (MR of the 3rd degree, initially 0%, after 12 months 31%, after 36 months 71%; p <0.001) was observed even with an initially moderate expansion of the fibrous ring of the MV.


2005 ◽  
Vol 14 (12) ◽  
pp. 48-49
Author(s):  
T. Schachner ◽  
A. Zimmer ◽  
G. Nagele ◽  
G. Laufer ◽  
J. Bonatti

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Ayman Elbadawi ◽  
Mohammed Elzeneini ◽  
Islam Y Elgendy ◽  
Mohamed Omer ◽  
Gbolahan O Ogunbayo ◽  
...  

Introduction: There is paucity of data on the outcomes of coronary artery bypass grafting (CABG) among patients presenting with ST-segment elevation myocardial infarction (STEMI). Methods: We queried the National Inpatient Sample database (2002-2016) for patients with STEMI who underwent CABG. We reported the trends in utilization of CABG for STEMI, and the associated in-hospital outcomes. Using multivariable analysis, we compared in-hospital outcomes in patients undergoing CABG on hospitalization day 1 vs. day 2 vs. day ≥3 , in the early (2002 to 2009) and contemporary cohorts (2012 to 2016). Results: Our analysis yielded 2,910,960 patients with STEMI, of whom 7.6% underwent CABG (9.6% in 2002 versus 3.9% in 2016, P trend <0.001). There was an increase in in-hospital mortality (5.8% in 2002 versus 7.6% in 2016, P trend <0.001) which corresponded to an increase in comorbidities burden among patients undergoing CABG. There was a rising trend in performing CABG on hospitalization day ≥ 3 corresponding to an increase in the utilization of MCS and pre-CABG PCI during the study years. CABG was more likely to be performed on admission day 1 in patients with anterior STEMI, cardiogenic shock or mechanical complications. In the early cohort, CABG on day 1 and day 2 was associated with higher in-hospital mortality, while in the contemporary cohort only CABG on day 1 was associated with higher in-hospital mortality compared with CABG on day ≥ 3. CABG on day 1 was associated with higher rate of cardiac arrest, hemorrhagic stroke, blood transfusion and cardiac tamponade in the earlier cohort, while in the more contemporary cohort it was associated with higher blood transfusion. Conclusions: There was a downtrend in performing CABG for STEMI, and an uptrend in in-hospital mortality after CABG. Patients undergoing emergent CABG on day 1 were more likely to have mechanical complications and cardiogenic shock and were associated with higher in-hospital mortality.


1999 ◽  
Vol 8 (3) ◽  
pp. 149-153 ◽  
Author(s):  
MA Goldsborough ◽  
MH Miller ◽  
J Gibson ◽  
S Creighton-Kelly ◽  
CA Custer ◽  
...  

BACKGROUND: The reported prevalence of leg wound complications after coronary artery bypass grafting is 2% to 24%. Decreased length of hospital stay for patients who have this surgical procedure poses new care requirements in both acute care and community settings. OBJECTIVE: To determine the prevalence of postoperative leg wound complications in patients undergoing coronary artery bypass grafting and the risk factors associated with these complications. METHOD: In this prospective, observational study, 547 consecutive patients who had coronary artery bypass grafting alone or in combination with other cardiac surgical procedures were examined for evidence of leg wound complications each day after surgery during hospitalization. After discharge, problems were detected by home care nurses. RESULTS: The prevalence of leg wound complications was 6.8%. Factors significant by multiple logistic regression included preoperative hospitalization, use of an Ace elastic bandage in the operating room, the length of time the leg incision remained open in the operating room, and administration of nicardipine intravenously in the intensive care unit. Odds ratios were calculated for each variable. Premorbid factors such as diabetes or peripheral vascular disease were not predictive of complications. On average, most problems occurred on postoperative day 10, when many patients were at home. CONCLUSIONS: The results highlight the need to detect complications early, in both the hospital and the community settings. The determination of factors related to poor outcomes may assist clinicians in improving healthcare delivery.


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