Methotrexate in ocular manifestations of Behcet's disease: a longitudinal study up to 15 years

2013 ◽  
Vol 16 (5) ◽  
pp. 568-577 ◽  
Author(s):  
Fereydoun Davatchi ◽  
Hormoz Shams ◽  
Farhad Shahram ◽  
Abdolhadi Nadji ◽  
Cheyda Chams-Davatchi ◽  
...  
2005 ◽  
Vol 8 (2) ◽  
pp. 119-123 ◽  
Author(s):  
Fereydoun DAVATCHI ◽  
Hormoz SHAMS ◽  
Farhad SHAHRAM ◽  
Abdol-Hadi NADJI ◽  
Ahmad-Reza JAMSHIDI ◽  
...  

2016 ◽  
Vol 7 (1) ◽  
pp. 141-147 ◽  
Author(s):  
Roy Schwartz ◽  
Sara Borok ◽  
Michaella Goldstein ◽  
Anat Kesler ◽  
Keren Regev ◽  
...  

Purpose: To report a unique case of Behçet's disease that presented with atypical ocular manifestations. Methods: Case report. Results: A 23-year-old homosexual male presented with bilateral anterior uveitis, vitritis, neuroretinitis and a unilateral superior hemivein occlusion with frosted branch angiitis pattern. These were accompanied by systemic findings of recurrent oral aphthous ulcers, erythema nodosum, and neurological and gastrointestinal involvement. A positive HLA-B51 examination supported the diagnosis of Behçet's disease. Conclusion: Neuroretinitis and frosted branch angiitis may be the clinical manifestations of Behçet's disease and may present simultaneously.


2019 ◽  
Vol 2019 (7) ◽  
Author(s):  
Dimos Merinopoulos ◽  
Janak Saada ◽  
Colin Jones ◽  
Chetan Mukhtyar

Abstract A 25-year-old woman presented with ophthalmic and neurological manifestations. Her ocular manifestations included bilateral uveitis, multifocal retinal phlebitis, vitreitis and multiple retinal haemorrhages. Her neurological manifestations included migrainous headaches with visual aura, transient sensory symptoms and posterior circulation Transient Ischemic Attack (TIA). Magnetic resonance imaging of the brain demonstrated lesions that involved the deep white matter lesions initially and progressed to also involve the juxta cortical white and deep grey matter and brain stem, but without further neurological manifestations. She was sequentially treated with intravenous and oral glucocorticoid, cyclophosphamide and mycophenolate mofetil, but she continued to suffer with persistent episodes of retinal haemorrhages. Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL), Susac syndrome and Behcet’s disease were considered in the differential diagnosis. Genetic workup and clinical picture were not suggestive of the former two. Further history of oro-genital ulceration in younger age emerged, which pointed strongly towards a diagnosis of Behcet’s disease with neurological involvement. She was treated with infliximab and methotrexate with complete resolution of her symptoms and withdrawal of corticosteroids for the first time in over two decades.


2010 ◽  
Vol 30 (4) ◽  
pp. 541-547 ◽  
Author(s):  
Fereydoun Davatchi ◽  
Farhad Shahram ◽  
Hormoz Shams ◽  
Abdolhadi Nadji ◽  
Cheyda Chams-Davatchi ◽  
...  

2013 ◽  
Vol 71 (Suppl 3) ◽  
pp. 682.13-682
Author(s):  
R.G. Goloeva ◽  
Z. Alekberova ◽  
V. Tankovskyi ◽  
I. Guseva

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