scholarly journals Impact of thoracic radiation therapy after chemotherapy on survival in extensive‐stage small cell lung cancer: A propensity score‐matched analysis

2019 ◽  
Vol 10 (4) ◽  
pp. 799-806
Author(s):  
Lei Deng ◽  
ZongMei Zhou ◽  
ZeFen Xiao ◽  
DongFu Chen ◽  
QinFu Feng ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Radiation Therapy ◽  
Propensity Score ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Thoracic Radiation ◽  
Extensive Stage

scholarly journals Aggressive Palliation in Extensive Stage Small Cell Lung Cancer, Practice Guidelines versus Clinical Practice: A Case Report and Review of the Literature

2011 ◽  
Vol 2011 ◽  
pp. 1-4
Author(s):  
Edward F. Miles ◽  
Laura L. Jacimore ◽  
John W. Nelson
Keyword(s):  
Lung Cancer ◽  
Radiation Therapy ◽  
Small Cell Lung Cancer ◽  
Metastatic Disease ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Response To Chemotherapy ◽  
Thoracic Radiation ◽  
Extensive Stage

Small cell lung cancer (SCLC) constitutes approximately 16% of all primary lung cancers, with more than 35,000 new cases per year. Two-thirds of patients present with extensive stage disease (ES-SCLC) due to a tendency to metastasize early. Outcomes remain poor, with a median survival of approximately 10 months and a two-year overall survival of <10%. Current recommendations call for combination chemotherapy alone in patients without localized symptoms. Thoracic radiation therapy following a good clinical response is controversial. We report on a patient with ES-SCLC that had an excellent response to chemotherapy and underwent whole brain radiotherapy for a known brain metastasis and consolidative radiotherapy to the thorax. His latest follow-up demonstrates only a stable residual pulmonary nodule and no evidence of active metastatic disease. ES-SCLC is a relatively common presentation with a variable burden of metastatic disease. In the absence of randomized trials demonstrating the efficacy of thoracic radiation therapy, the community radiation oncologist is placed in a difficult position when addressing these patients, particularly those with otherwise good performance status and a good response to initial systemic chemotherapy. More research in this area is sorely needed to help guide treatment recommendations.

Thoracic radiation therapy could give survival benefit to elderly patients with extensive-stage small-cell lung cancer

2017 ◽  
Vol 13 (13) ◽  
pp. 1149-1158 ◽  
Author(s):  
Changchun An ◽  
Wang Jing ◽  
Yan Zhang ◽  
Sujing Liu ◽  
Haiyong Wang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Radiation Therapy ◽  
Elderly Patients ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Survival Benefit ◽  
Small Cell ◽  
Small Cell Lung ◽  
Thoracic Radiation ◽  
Extensive Stage
Sign in / Sign up

Export Citation Format

Share Document