Characterization of CD4 + T cell subsets and HIV susceptibility in the inner and outer foreskin of Ugandan men

2019 ◽  
Vol 82 (1) ◽  
Author(s):  
Ronald Moses Galiwango ◽  
Sergey Yegorov ◽  
Vineet Joag ◽  
Jessica Prodger ◽  
Kamnoosh Shahabi ◽  
...  
Keyword(s):  
T Cell ◽  
T Cell Subsets ◽  
Cd4 T Cell ◽  
Hiv Susceptibility

scholarly journals Characterization of HIV-induced remodeling reveals differences in infection susceptibility of memory CD4+ T cell subsets in vivo

Cell Reports ◽  
2021 ◽  
Vol 35 (4) ◽  
pp. 109038
Author(s):  
Guorui Xie ◽  
Xiaoyu Luo ◽  
Tongcui Ma ◽  
Julie Frouard ◽  
Jason Neidleman ◽  
...  
Keyword(s):  
T Cell ◽  
T Cell Subsets ◽  
Cd4 T Cell ◽  
Infection Susceptibility

scholarly journals Characterization of CD4+ T cell subsets in allergy

2012 ◽  
Vol 24 (6) ◽  
pp. 700-706 ◽  
Author(s):  
Erik Wambre ◽  
Eddie A James ◽  
William W Kwok
Keyword(s):  
T Cell ◽  
T Cell Subsets ◽  
Cd4 T Cell

scholarly journals Characterization of mouse CD4 T cell subsets defined by expression of KLRG1

2007 ◽  
Vol 37 (12) ◽  
pp. 3445-3454 ◽  
Author(s):  
Niklas Beyersdorf ◽  
Xin Ding ◽  
Julia K. Tietze ◽  
Thomas Hanke
Keyword(s):  
T Cell ◽  
T Cell Subsets ◽  
Cd4 T Cell

scholarly journals Characterization of a Human Cervical CD4+T Cell Subset Coexpressing Multiple Markers of HIV Susceptibility

2011 ◽  
Vol 187 (11) ◽  
pp. 6032-6042 ◽  
Author(s):  
Lyle R. McKinnon ◽  
Billy Nyanga ◽  
Duncan Chege ◽  
Preston Izulla ◽  
Makobu Kimani ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Subset ◽  
Cd4 T Cell ◽  
T Cell Subset ◽  
Hiv Susceptibility ◽  
Multiple Markers

scholarly journals Characterization of CD4+ T Cell Subsets in Patients with Abdominal Aortic Aneurysms

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Fábio Haach Téo ◽  
Rômulo Tadeu Dias de Oliveira ◽  
Liana Villarejos ◽  
Ronei Luciano Mamoni ◽  
Albina Altemani ◽  
...  
Keyword(s):  
T Cell ◽  
Mononuclear Cells ◽  
Aortic Aneurysms ◽  
T Cell Subsets ◽  
Cd4 T Cell ◽  
Peripheral Blood Mononuclear ◽  
Abdominal Aortic ◽  
Tissue Degradation

Background. The mediators produced by CD4+ T lymphocytes are involved in the pathogenesis of aneurysmal lesions in abdominal aortic aneurysm (AAA) patients. The aim of this study was to identify and characterize the CD4+ T cell subsets involved in human AAA. Methods. The CD4+ T cell subsets in 30 human aneurysmal lesions were determined using flow cytometry (FC) and immunohistochemistry (IHC). The peripheral blood mononuclear cells (PBMCs) from patients with AAA were also analyzed by FC and compared with control subjects. Results. Human aneurysmal lesions contained IFN-γ, IL-12p35, IL-4, IL-23p19, IL-17R, and IL-22 positive cells. PBMCs from AAA patients had higher expression levels of IFN-γ, TNF-α, IL-4, and IL-22 when compared to controls. Conclusions. Our results show the presence of TH1, TH2, TH17, and TH22 subsets in aneurysmal lesions of AAA patients and suggest that these cells may be mainly activated in situ, where they can induce tissue degradation and contribute to the pathogenesis of AAA.

Preferential HIV Susceptibility of Specific CD4+ T Cell Subsets in the Cervix

2014 ◽  
Vol 30 (S1) ◽  
pp. A47-A47
Author(s):  
Vineet R. Joag ◽  
Lyle R. McKinnon ◽  
Segen Kidane ◽  
Mark Yudin ◽  
Steve Kimwaki ◽  
...  
Keyword(s):  
T Cell ◽  
T Cell Subsets ◽  
Cd4 T Cell ◽  
Hiv Susceptibility

scholarly journals Traditional Thai Massage Promoted Immunity in the Elderly via Attenuation of Senescent CD4+ T Cell Subsets: A Randomized Crossover Study

2021 ◽  
Vol 18 (6) ◽  
pp. 3210
Author(s):  
Kanda Sornkayasit ◽  
Amonrat Jumnainsong ◽  
Wisitsak Phoksawat ◽  
Wichai Eungpinichpong ◽  
Chanvit Leelayuwat
Keyword(s):  
T Cells ◽  
T Cell ◽  
Crossover Study ◽  
Intracellular Cytokine Staining ◽  
The Elderly ◽  
Complementary Therapy ◽  
T Cell Subsets ◽  
Cd4 T Cell ◽  
T Subsets ◽  
Randomized Crossover Study

The beneficial physiological effects of traditional Thai massage (TTM) have been previously documented. However, its effect on immune status, particularly in the elderly, has not been explored. This study aimed to investigate the effects of multiple rounds of TTM on senescent CD4+ T cell subsets in the elderly. The study recruited 12 volunteers (61–75 years), with senescent CD4+ T cell subsets, who received six weekly 1-h TTM sessions or rest, using a randomized controlled crossover study with a 30-day washout period. Flow cytometry analysis of surface markers and intracellular cytokine staining was performed. TTM could attenuate the senescent CD4+ T cell subsets, especially in CD4+28null NKG2D+ T cells (n = 12; p < 0.001). The participants were allocated into two groups (low < 2.75% or high ≥ 2.75%) depending on the number of CD4+28null NKG2D+ T cells. After receiving TTM over 6 sessions, the cell population of the high group had significantly decreased (p < 0.001), but the low group had no significant changes. In conclusion, multiple rounds of TTM may promote immunity through the attenuation of aberrant CD4+ T subsets. TTM may be provided as a complementary therapy to improve the immune system in elderly populations.

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