Seminal vesicles of infertile patients with male accessory gland infection: ultrasound evaluation after prolonged treatment with tadalafil, a selective phosphodiesterase-5 inhibitor

Andrologia ◽  
2012 ◽  
Vol 45 (6) ◽  
pp. 386-391 ◽  
Author(s):  
S. La Vignera

Andrology ◽  
2012 ◽  
Vol 1 (2) ◽  
pp. 245-250 ◽  
Author(s):  
S. La Vignera ◽  
R. A. Condorelli ◽  
E. Vicari ◽  
F. Lotti ◽  
V. Favilla ◽  
...  


2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Rosita A. Condorelli ◽  
Enzo Vicari ◽  
Laura M. Mongioi ◽  
Giorgio I. Russo ◽  
Giuseppe Morgia ◽  
...  

This study evaluated the ultrasound (US) features of 20 patients with MAGI and concomitantpapilloma virus(HPV) infection compared to 20 patients with microbial (presence ofChlamydia trachomatisalone) MAGI and 20 patients with amicrobial (inflammatory) MAGI. Patients with HPV infection showed significantly (p<0.05) higher total prostate, seminal vesicles, and epididymal US signs (18.0 ± 2.0) compared to the other 2 groups (12.0 ± 4.0 versus 10.0 ± 3.0, resp.). In addition, patients with MAGI and HPV had a higher prevalence of complicated forms of MAGI [prostatovesiculitis (PV) and prostate-vesiculo-epididymitis (PVE)] and a higher frequency of the fibrosclerotic variant compared to the other groups (70.0 ± 10.0% versus 48.0 ± 5.0% versus 15.0 ± 10.0%). Moreover, HPV infected patients had a higher number of US criteria suggestive for MAGI in the periurethral region of the prostate compared to the other groups. In particular, the patients showed a higher ratio between periurethral and lobar US criteria distribution (5.0 versus 0.5). Finally, the seminal fluid concentration ofCD45posleukocytes (2.0 ± 0.2 versus 1.3 ± 0.3 versus 1.0 ± 0.3 mil/mL) was significantly higher and sperm progressive motility was significantly lower in these patients compared to other groups.



1981 ◽  
Vol 59 (3) ◽  
pp. 332-346 ◽  
Author(s):  
J. R. Linley

This paper describes the initial stages of sperm transfer in Culicoides melleus. A description of the male and female reproductive tracts is given and an account of events during the first 2 min of coitus. In this period the male secretes a spermatophore, which, during copulation, is held predominantly in the male genitalia. The course of ejaculation, involving passage of spermatozoa through the seminal vesicles and glutinous glands of the male accessory gland, and subsequently through the ejaculatory ducts, is described. Extrusion of the spermatophore at the aedeagus is illustrated and an explanation advanced to account for encapsulation of the sperm masses. The structure and content of the spermatophore is described with the aid of electron micrographs. A feature of particular interest is the "membrane complex," secreted prior to ejaculation by cells of the glutinous glands. The complex consists of a layer of membranes, which separates the ejaculate from the spermatophore walls.



Andrology ◽  
2021 ◽  
Author(s):  
Sandro La Vignera ◽  
Andrea Crafa ◽  
Rosita A. Condorelli ◽  
Federica Barbagallo ◽  
Laura M. Mongioì ◽  
...  


2021 ◽  
pp. 205141582098768
Author(s):  
Hosam A. Noweir ◽  
Vaibhav Modgil ◽  
Ian Pearce

Male accessory gland infection (MAGI) is a generic acronym indicating inflammatory conditions affecting the prostate gland, seminal vesicles, the ductus deferens and the epididymis. It is a frequent disease, mostly with a chronic course. Majority of the MAGIs remain asymptomatic, thereby leading to a debate whether to treat these patients or not. The primary criterion for MAGI was suggested by Comhaire and colleagues in 1980. The role of MAGI in causing infertility and sexual dysfunctions has long been a matter of debate. The most recent studies show that MAGI could alter, with various mechanisms, both conventional and biofunctional sperm parameters, and determine worst reproductive outcome. This article provides an overview of up-to-date research findings about MAGI with special focus on data published on its impact on fertility; and diagnostic criteria including cellular and seminal biomarkers along with the promising results of emerging proteomic platforms for the identification of MAGI.



2011 ◽  
Vol 35 (2) ◽  
pp. 183-189 ◽  
Author(s):  
E. Vicari ◽  
A. E. Calogero ◽  
R. A. Condorelli ◽  
L. O. Vicari ◽  
S. La Vignera


2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Sandro La Vignera ◽  
Rosita A. Condorelli ◽  
Laura M. Mongioi ◽  
Aldo E. Calogero

Aim of this study was to evaluate the effects of pharmacological treatment with Tadalafil 5 mg daily on symptoms and quality of sperm parameters in selected patients with amicrobic MAGI (male accessory gland inflammation). 120 patients with amicrobic MAGI (mean age 27.0 ± 6.0 years) with mild-moderate ED (erectile dysfunction) according to IIEF-5 (International Index of Erectile Function 5 Items) scores underwent pharmacological treatment with Tadalafil 5 mg daily for six months. Before and after treatment these patients were evaluated through IIEF-5, semen analysis (according to WHO Criteria, 2010), SI-MAGI (Structured Interview about Male Accessory Gland Inflammation), and ultrasound evaluation. Patients with PVE (prostate-vesciculo-epididymitis) showed a significant increase in the percentage of spermatozoa with total (16.0 ± 8.0 versus 30.0 ± 6.0%) and progressive motility (8.00 ± 10.0 versus 25.0 ± 6.00%). It was a significant reduction of the number of patients with complicated ultrasound forms (30.0 versus 52.0) and a significant increase of the number of patients with uncomplicated ultrasound form (90.0 versus 68.0). Finally, there was a significant reduction in the percentage of patients with alterations of sexual function different from DE, such as premature ejaculation (4.00 versus 8.00%), painful ejaculation (4.00 versus 10.0%), delayed ejaculation (12.50 versus 8.00%), and decreased libido (10.0 versus 25.0%).



2011 ◽  
Vol 49 (08) ◽  
Author(s):  
P Deibert ◽  
S Eggerking ◽  
L Kupcinskas ◽  
J Sumskiene ◽  
R Mohrbacher ◽  
...  


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