Transplant Kidney Biopsy for Proteinuria with Stable Creatinine: Findings and Outcomes

2021 ◽  
Author(s):  
Sandesh Parajuli ◽  
Kurt Swanson ◽  
James Alstott ◽  
Fahad Aziz ◽  
Neetika Garg ◽  
...  
Keyword(s):  
Kidney Biopsy ◽  
Transplant Kidney

Pre-discharge, post-transplant kidney biopsy does not predict rejection

1982 ◽  
Vol 32 (3) ◽  
pp. 269-274 ◽  
Author(s):  
A.J. Matas ◽  
R. Sibley ◽  
S.M. Mauer ◽  
Y. Kim ◽  
D.E.R. Sutherland ◽  
...  
Keyword(s):  
Kidney Biopsy ◽  
Post Transplant ◽  
Transplant Kidney

Risk of bleeding with transplant kidney biopsy followed by apheresis – A single center’s experience

2020 ◽  
Vol 93 (6) ◽  
pp. 305-306
Author(s):  
Tiffany Wong ◽  
Nicole Aqui ◽  
Abdallah S. Geara
Keyword(s):  
Kidney Biopsy ◽  
Risk Of Bleeding ◽  
Transplant Kidney

scholarly journals The First Transplant Kidney Biopsy Ever Performed

2013 ◽  
Vol 13 (5) ◽  
pp. 1367-1368 ◽  
Author(s):  
H. Kreis ◽  
L.-H. Noël ◽  
C. Legendre
Keyword(s):  
Kidney Biopsy ◽  
Transplant Kidney

scholarly journals PREDICTING GRAFT OUTCOME WITH EVALUATION OF PRE-TRANSPLANT KIDNEY BIOPSY USING A CUMULATIVE PATHOLOGY SCORE

2008 ◽  
Vol 86 (Supplement) ◽  
pp. 20
Author(s):  
R B. Munivenkatappa ◽  
J C. Papadimitriou ◽  
C B. Drachenberg ◽  
A Haririan ◽  
F Rasetto ◽  
...  
Keyword(s):  
Kidney Biopsy ◽  
Graft Outcome ◽  
Transplant Kidney

The Management of Arterio-Venous Malformations Following Transplant Kidney Biopsy

2012 ◽  
Vol 94 (10S) ◽  
pp. 876
Author(s):  
R. Dave ◽  
C. Ecuyer ◽  
L. Hostert ◽  
M. Attia ◽  
K. Menon ◽  
...  
Keyword(s):  
Kidney Biopsy ◽  
Venous Malformations ◽  
Transplant Kidney

scholarly journals Histological Evaluation of Extended Criteria Donors: Donor’s Kidney Biopsy and Graft Outcome after 5 Years of Transplantation

2020 ◽  
Vol 4 (2) ◽  
pp. 61-66
Author(s):  
Paolo Carta ◽  
Emma Bartaletti ◽  
Giulia Ghiandai ◽  
Leonardo Caroti ◽  
Aida Larti ◽  
...  
Keyword(s):  
Kidney Biopsy ◽  
Graft Loss ◽  
Histological Evaluation ◽  
Kidney Graft ◽  
Graft Outcome ◽  
Histological Score ◽  
Transplant Kidney ◽  
Single Kidney ◽  
Marginal Donors

Pre-transplant kidney biopsy is routinely used to decide whether kidneys from marginal donors should be transplanted as single or double trans-plantation. This is a 5-year extension of the follow-up of a previous study. In that study, graft outcomes were compared retrospectively between a group of 44 recipients of a single kidney graft from an extended criteria donor and a Karpinski histological score of 3 or less, and another group of 56 recipients of a single transplant with a Karpinski histological score of 4 or 5. After 5 years of transplantation, there was no difference between the two groups in terms of recipient’s serum creatinine levels (1.8 ± 0.5 vs 1.9 ± 0.6 mg/dL, P = 0.5), creatinine clearance (53 ± 23 vs 49 ± 27.0 mL/min, P = 0.6), or the rates of graft loss (41% vs 49%,P = 0.5). Therefore, the choice between single and double transplant should not be made only on the basis of histological score but should be done together with the evaluation of donor’s clinical parameters, especially the renal function.

scholarly journals MO090TRANSPLANT KIDNEY BIOPSY FINDINGS IN COVID-19: A SYSTEMATIC REVIEW

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Henry Wu ◽  
Vishnu Jeyalan ◽  
Rajkumar Chinnadurai ◽  
Arvind Ponnusamy
Keyword(s):  
Renal Biopsy ◽  
Kidney Biopsy ◽  
Single Case ◽  
Wide Spectrum ◽  
Case Reports ◽  
Case Series ◽  
Antibody Mediated Rejection ◽  
Early Results ◽  
Transplant Kidney ◽  
Transplanted Kidneys

Abstract Background and Aims Patients with transplanted kidneys are more susceptible to COVID-19 infections compared to those with native kidneys because of chronic immunosuppression and co-existing co-morbidities. A wide spectrum of renal pathologies has been reported from renal biopsies taken from patients with native kidneys following COVID-19 presentation. In comparison, biopsy-proven findings in the setting of kidney transplantation and COVID-19 diagnosis are seldom described. Our study aims to review early reported histological findings of transplant kidney biopsies from patients testing positive for COVID-19. Method This is a secondary analysis of a larger study (PROSPERO registration number: CRD42020218048) which reviewed the histopathological findings of kidney biopsies in adults with concurrent COVID-19 infection. A systematic literature search was conducted independently by two authors (HW, VJ) through ‘PubMed’, ‘Web of Science’, ‘Embase’ and ‘Medline-ProQuest’ using the following keywords: “COVID-19 AND Kidney Biopsy”, “COVID-19 AND Renal Biopsy”, “SARS-CoV-2 AND Kidney Biopsy” and “SARS-CoV-2 AND Renal Biopsy”. Articles were screened by three authors (HW, VJ, RC) for relevance and duplicates were removed. The study selection process was carried out as per the PRISMA guideline. In this analysis, we included all research articles reporting biopsies in transplanted kidneys in adults over age > 18 who tested positive with COVID-19 following a PCR swab test. We only included articles published in the English language. All relevant articles published before November 1st 2020 were included in this review. Information regarding demographic data, co-morbidities, renal presentation, renal parameters at time of COVID-19 diagnosis, management, need for renal replacement therapy and outcomes were extracted from selected articles. Results Our review identified 11 cases reporting transplant kidney biopsies in patients with positive COVID-19 status. These 11 cases were reported from 7 articles, which were either single case reports or part of a case series. Mean age of the reported cases was 43.6 years ± 10.7. Transplant kidney biopsies were taken from 4 female and 7 male patients, where 7 patients were of black ethnicity. The review involved 3 live donor and 6 deceased donor transplanted kidneys, and 2 cases did not report type of kidney transplant received. All of the documented cases presented with acute kidney injury. 9 patients have essential hypertension or hypertension secondary to other co-morbidities. Biopsy findings revealed 2 cases of acute T-cell mediated and antibody mediated rejection, 2 cases of acute tubular injury, 5 cases of either FSGS or collapsing FSGS and 1 report of post-transplant kidney infarction. Acute treatment received involved different regimes. All 11 patients were eventually discharged from hospital, where 2 patients required dialysis following discharge. Table 1 describes data from the extracted cases. Conclusion There are multiple histological pathologies observed amongst transplant kidney biopsies taken from patients admitted following COVID-19 diagnosis. Early results suggest aggressive medical treatment to manage inflammation, transplant rejection and co-morbidities such as hypertension may optimize general and renal-specific outcomes. Collation of further cases is required to determine a clearer association between COVID-19 and characteristics demonstrated from transplant kidney biopsies.

scholarly journals Bleeding Complications after Pediatric Kidney Biopsy

2018 ◽  
Vol 14 (1) ◽  
pp. 57-65 ◽  
Author(s):  
Charles D. Varnell ◽  
Hillarey K. Stone ◽  
Jeffrey A. Welge
Keyword(s):  
Blood Transfusion ◽  
Confidence Interval ◽  
Pediatric Patients ◽  
Kidney Biopsy ◽  
Meta Analysis ◽  
Secondary Analysis ◽  
Outpatient Setting ◽  
Bleeding Complications ◽  
Additional Intervention ◽  
Transplant Kidney

Background and objectivesKidney biopsy is an essential tool for the diagnosis and treatment of patients with kidney disease; however, because of its invasive nature, bleeding complications may arise.Design, setting, participants, & measurementsWe performed a meta-analysis of prospective or retrospective observational studies and randomized, controlled trials in pediatric patients undergoing native or transplant kidney biopsy in an inpatient or outpatient setting in MEDLINE-indexed studies from January 1998 to November 1, 2017 to determine the proportion of patients who develop hematoma, need blood transfusion, or need an additional intervention due to a complication after kidney biopsy.ResultsTwenty-three studies of 5504 biopsies met inclusion criteria. The proportion of patients developing hematoma after biopsy was between 11% (95% confidence interval, 7% to 17%) and 18% (95% confidence interval, 9% to 35%) using two analyses that included different time periods. The proportion needing blood transfusion was 0.9% (95% confidence interval, 0.5% to 1.4%). The proportion needing an additional intervention due to postbiopsy complication was 0.7% (95% confidence interval, 0.4% to 1.1%). Secondary analysis was not possible due to lack of data in the original manuscripts on laboratory values, needle gauges, number of needle passes, age of patient, or performer (attending versus trainee). Analysis with metaregression found that use of real-time ultrasound during biopsy did not modify the risk for hematoma, requirement of a blood products transfusion, or requirement of an additional procedure after biopsy. Analysis with metaregression comparing native biopsies with transplant biopsies did not reveal that biopsy type (native kidney biopsy versus transplant kidney biopsy) was associated with the need for a blood transfusion or requirement of an additional intervention after biopsy.ConclusionsThe development of perinephric hematoma after kidney biopsy is not an infrequent finding. The proportion of patients requiring blood transfusion or needing an additional intervention as a result of kidney biopsy in pediatric patients is significantly smaller.

The First Transplant Kidney Biopsy Ever Performed

2013 ◽  
pp. n/a-n/a
Author(s):  
H. Kreis ◽  
L.-H. Noël ◽  
C. Legendre
Keyword(s):  
Kidney Biopsy ◽  
Transplant Kidney
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