scholarly journals Effect of cenobamate on the single‐dose pharmacokinetics of multiple cytochrome P450 probes using a cocktail approach in healthy subjects

2021 ◽  
Author(s):  
Stephen A. Greene ◽  
Charles Kwak ◽  
Marc Kamin ◽  
Laurent Vernillet ◽  
Kelli J. Glenn ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Single Dose ◽  
Healthy Subjects ◽  
Cocktail Approach

scholarly journals Effect of Short-Term Fasting on Systemic Cytochrome P450-Mediated Drug Metabolism in Healthy Subjects: A Randomized, Controlled, Crossover Study Using a Cocktail Approach

2017 ◽  
Vol 56 (10) ◽  
pp. 1231-1244 ◽  
Author(s):  
Laureen A. Lammers ◽  
Roos Achterbergh ◽  
Ron H. N. van Schaik ◽  
Johannes A. Romijn ◽  
Ron A. A. Mathôt
Keyword(s):  
Cytochrome P450 ◽  
Drug Metabolism ◽  
Crossover Study ◽  
Healthy Subjects ◽  
Short Term ◽  
Randomized Controlled ◽  
Cocktail Approach

scholarly journals Effect of fermented red ginseng on cytochrome P450 and P‐glycoprotein activity in healthy subjects, as evaluated using the cocktail approach

2016 ◽  
Vol 82 (6) ◽  
pp. 1580-1590 ◽  
Author(s):  
Min‐Gul Kim ◽  
Yunjeong Kim ◽  
Ji‐Young Jeon ◽  
Dal‐Sik Kim
Keyword(s):  
Cytochrome P450 ◽  
Healthy Subjects ◽  
Red Ginseng ◽  
P Glycoprotein ◽  
Cocktail Approach

Effect of Cytochrome P450 and ABCB1 Polymorphisms on Imatinib Pharmacokinetics After Single-Dose Administration to Healthy Subjects

2020 ◽  
Vol 40 (7) ◽  
pp. 617-628 ◽  
Author(s):  
María Ángeles Pena ◽  
Javier Muriel ◽  
Miriam Saiz-Rodríguez ◽  
Alberto M. Borobia ◽  
Francisco Abad-Santos ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Single Dose ◽  
Healthy Subjects ◽  
Dose Administration ◽  
Single Dose Administration

Pharmacokinetics and dopamine d2 and serotonin 5-ht2a receptor occupancy of paliperidone in healthy subjects: two open-label, single-dose studies (PAL-115)

2007 ◽  
Vol 40 (05) ◽  
Author(s):  
P Karlsson ◽  
L Hargarter ◽  
E Dencker ◽  
S Nyberg ◽  
E Mannaert ◽  
...  
Keyword(s):  
Single Dose ◽  
Healthy Subjects ◽  
Receptor Occupancy ◽  
Open Label ◽  
Dopamine D2

In vivo Phenotyping Methods: Cytochrome P450 Probes with Emphasis on the Cocktail Approach

2017 ◽  
Vol 23 (14) ◽  
Author(s):  
Guillermo Alberto Keller ◽  
María Laura Ferreirós Gago ◽  
Roberto Alejandro Diez ◽  
Guillermo Di Girolamo
Keyword(s):  
Cytochrome P450 ◽  
Cocktail Approach

The effect of AST-120 on the single-dose pharmacokinetics of metoprolol extended-release tablets in healthy subjects

2014 ◽  
Vol 29 (2) ◽  
Author(s):  
Shinsuke Inoue ◽  
Miho Shimizu ◽  
Kiyoshi Arita ◽  
Kei Akimoto
Keyword(s):  
Single Dose ◽  
Healthy Subjects ◽  
Extended Release

scholarly journals Single-dose pharmacokinetics and tolerability of pegylated interferon-α2b in young and elderly healthy subjects

2003 ◽  
Vol 56 (1) ◽  
pp. 131-134 ◽  
Author(s):  
Samir K. Gupta ◽  
Paul Glue ◽  
Sheila Jacobs ◽  
Donna Belle ◽  
Melton Affrime
Keyword(s):  
Single Dose ◽  
Healthy Subjects ◽  
Pegylated Interferon ◽  
Interferon Α2b

Pharmacokinetic Interactions of Rolapitant With Cytochrome P450 3A Substrates in Healthy Subjects

2018 ◽  
Vol 59 (4) ◽  
pp. 488-499 ◽  
Author(s):  
Xiaodong Wang ◽  
Jing Wang ◽  
Sujata Arora ◽  
Lorraine Hughes ◽  
Jennifer Christensen ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Healthy Subjects ◽  
Cytochrome P450 3A ◽  
Pharmacokinetic Interactions
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