scholarly journals Duodenal adenomatosis in Japanese patients with familial adenomatous polyposis

2014 ◽  
Vol 26 ◽  
pp. 30-34 ◽  
Author(s):  
Yuji Maehata ◽  
Motohiro Esaki ◽  
Minako Hirahashi ◽  
Takanari Kitazono ◽  
Takayuki Matsumoto
Keyword(s):  
Familial Adenomatous Polyposis ◽  
Japanese Patients ◽  
Adenomatous Polyposis ◽  
Duodenal Adenomatosis

scholarly journals Clinical outcomes of gastric polyps and neoplasms in patients with familial adenomatous polyposis

2017 ◽  
Vol 05 (03) ◽  
pp. E137-E145 ◽  
Author(s):  
Keiko Nakamura ◽  
Satoru Nonaka ◽  
Takeshi Nakajima ◽  
Tatsuo Yachida ◽  
Seiichiro Abe ◽  
...  
Keyword(s):  
Familial Adenomatous Polyposis ◽  
Clinical Outcomes ◽  
Japanese Patients ◽  
Gastrointestinal Diseases ◽  
Gastric Neoplasms ◽  
Fundic Gland ◽  
Adenomatous Polyposis ◽  
Gastric Lesions ◽  
Upper Gastrointestinal

Abstract Background and study aims Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome caused by a germline mutation in the adenomatous polyposis coli (APC) gene, characterized by the presence of more than 100 adenomatous polyps in the colorectum. The upper gastrointestinal tract is an extracolonic site for malignancy in patients with FAP. The frequency of death in Japanese patients with FAP because of gastric cancer is 2.8 % and that because of colon cancer is 60.6 %. Few studies have reported upper gastrointestinal diseases in patients with FAP. In the present study, we investigated the clinical outcomes of patients with FAP diagnosed with gastric neoplasms. Patients and methods We enrolled 80 patients with FAP who underwent esophagogastroduodenoscopy from October 1997 to December 2011. We investigated patient characteristics, endoscopic findings of gastric lesions, treatment outcomes, and long-term courses. Results Fundic gland polyposis was observed in 51 patients (64 %) and gastric neoplasms in 22 patients (28 %), including 20 with non-invasive and 2 with invasive neoplasm. Of the 26 neoplasms, 11 were treated by endoscopic resection (ER) and 4 by surgical resection. Metachronous gastric neoplasms were observed in 7 patients (15 lesions) and treated by ER, except for in 1 patient. No patients died of gastric lesions during a median follow-up period of 6.5 years (range, 0 – 14). Conclusion Because gastric lesions including gastric cancers in patients with FAP did not cause any deaths, they can be considered to have favorable prognoses. Early detection of gastric neoplasms through an appropriate follow-up interval may have contributed to these good outcomes.

Progressive Duodenal Adenomatosis in a Familial Adenomatous Polyposis Pedigree with APC Mutation at Codon 1556

2002 ◽  
Vol 45 (2) ◽  
pp. 229-233 ◽  
Author(s):  
Takayuki Matsumoto ◽  
Mitsuo Iida ◽  
Yoichiro Kobori ◽  
Mitsuru Mizuno ◽  
Shotaro Nakamura ◽  
...  
Keyword(s):  
Familial Adenomatous Polyposis ◽  
Adenomatous Polyposis ◽  
Duodenal Adenomatosis ◽  
Apc Mutation

Characteristics and Clinical Outcomes of Duodenal Neoplasia in Japanese Patients With Familial Adenomatous Polyposis

2017 ◽  
Vol 51 (5) ◽  
pp. 407-411 ◽  
Author(s):  
Tatsuo Yachida ◽  
Takeshi Nakajima ◽  
Satoru Nonaka ◽  
Keiko Nakamura ◽  
Haruhisa Suzuki ◽  
...  
Keyword(s):  
Familial Adenomatous Polyposis ◽  
Clinical Outcomes ◽  
Japanese Patients ◽  
Adenomatous Polyposis

Detoxification enzyme polymorphisms are not involved in duodenal adenomatosis in familial adenomatous polyposis

2007 ◽  
Vol 95 (4) ◽  
pp. 499-505 ◽  
Author(s):  
M. Berkhout ◽  
H. M. J. Roelofs ◽  
R. H. M. te Morsche ◽  
E. Dekker ◽  
J. H. J. M. van Krieken ◽  
...  
Keyword(s):  
Familial Adenomatous Polyposis ◽  
Adenomatous Polyposis ◽  
Detoxification Enzyme ◽  
Enzyme Polymorphisms ◽  
Duodenal Adenomatosis

scholarly journals Duodenal adenomatosis in familial adenomatous polyposis

Gut ◽  
2004 ◽  
Vol 53 (3) ◽  
pp. 381-386 ◽  
Author(s):  
S Bulow
Keyword(s):  
Familial Adenomatous Polyposis ◽  
Adenomatous Polyposis ◽  
Duodenal Adenomatosis

Surgical management for advanced duodenal adenomatosis and duodenal cancer in Dutch patients with familial adenomatous polyposis: A nationwide retrospective cohort study

Surgery ◽  
2012 ◽  
Vol 151 (5) ◽  
pp. 681-690 ◽  
Author(s):  
Bjorn W.H. van Heumen ◽  
Marry H. Nieuwenhuis ◽  
Harry van Goor ◽  
Lisbeth (E) M.H. Mathus-Vliegen ◽  
Evelien Dekker ◽  
...  
Keyword(s):  
Cohort Study ◽  
Familial Adenomatous Polyposis ◽  
Surgical Management ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Duodenal Cancer ◽  
Adenomatous Polyposis ◽  
Duodenal Adenomatosis

scholarly journals Endoscopic management of duodenal adenomatosis in familial adenomatous polyposis—A case‐based review

2021 ◽  
Author(s):  
E. Soons ◽  
T. M. Bisseling ◽  
M. C. A. van Kouwen ◽  
G. Möslein ◽  
P. D. Siersema
Keyword(s):  
Familial Adenomatous Polyposis ◽  
Endoscopic Management ◽  
Adenomatous Polyposis ◽  
Duodenal Adenomatosis ◽  
Case Based

scholarly journals Progression of duodenal adenomatosis in familial adenomatous polyposis: due to ageing of subjects and advances in technology

2011 ◽  
Vol 10 (3) ◽  
pp. 491-499 ◽  
Author(s):  
Elisabeth M. H. Mathus-Vliegen ◽  
Karam S. Boparai ◽  
Evelien Dekker ◽  
Nan van Geloven
Keyword(s):  
Familial Adenomatous Polyposis ◽  
Adenomatous Polyposis ◽  
Duodenal Adenomatosis
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