Personal treatment experience for severe generalized pustular psoriasis of pregnancy: two case reports

2013 ◽  
Vol 27 (3) ◽  
pp. 174-177 ◽  
Author(s):  
Li Luan ◽  
Shixin Han ◽  
Zhenying Zhang ◽  
Xiaoming Liu
2008 ◽  
Vol 12 (4) ◽  
pp. 184-188 ◽  
Author(s):  
Shannon B. Routhouska ◽  
Pranav B. Sheth ◽  
Neil J. Korman

Background: Infliximab, a tumor necrosis factor α antagonist, has recently been shown to be successful for the short-term treatment of generalized pustular psoriasis (GPP) in multiple case reports. Objective: The goal of this case series was to assess the efficacy of the longer-term management of GPP with infliximab. Methods: Three patients with severe GPP were followed to assess the efficacy of long-term treatment with infliximab. Results: Infliximab therapy was more efficacious with infusion every 6 to 8 weeks in combination with methotrexate. Conclusion: Infliximab may be efficacious for some patients for the long-term management of GPP. Maintaining a strict infliximab infusion schedule and concomitant methotrexate therapy may decrease infusion reactions and increase efficacy.


2016 ◽  
Vol 9 (2) ◽  
pp. 55-59 ◽  
Author(s):  
Aoibheann Flynn ◽  
Naomi Burke ◽  
Bridgette Byrne ◽  
Noreen Gleeson ◽  
Bairbre Wynne ◽  
...  

Generalized pustular psoriasis of pregnancy is a rare dermatosis with potential serious consequences for both the mother and fetus. Treatment is difficult and historically steroids were the mainstay of treatment. Cyclosporin has been used for a few cases resistant to steroids. We report our own experience of two cases of generalized pustular psoriasis of pregnancy. Cases of generalized pustular psoriasis of pregnancy need review by a dermatologist with experience of skin disorders in pregnancy. Both the fetus and mother need to be monitored closely when systemic illness occurs, as there is a risk of stillbirth. Maternal sepsis is a known complication of generalized pustular psoriasis of pregnancy. Cyclosporin, when used appropriately is effective and relatively safe.


2020 ◽  
Vol 48 (3) ◽  
pp. 030006052091209
Author(s):  
Jiajing Lu ◽  
Ying Li ◽  
Ning Yu ◽  
Fujuan Chen ◽  
Yangfeng Ding ◽  
...  

1979 ◽  
Vol 115 (10) ◽  
pp. 1215-1216 ◽  
Author(s):  
F. R. Murphy

1999 ◽  
Vol 61 (2) ◽  
pp. 144-147
Author(s):  
Miyako KUDO ◽  
Yoshihiro UMEBAYASHI ◽  
Tomoe KOTSUJI ◽  
Fujio OTSUKA

2013 ◽  
Vol 75 (6) ◽  
pp. 504-507
Author(s):  
Reiko TSUTSUMI ◽  
Koji ADACHI ◽  
Yuichi YOSHIDA ◽  
Osamu YAMAMOTO

2001 ◽  
Vol 63 (3) ◽  
pp. 248-251 ◽  
Author(s):  
Tomomi NAKATANI ◽  
Minoru TAKATA ◽  
Shigeru KAWARA ◽  
Kiyoshi UCHIDA

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