Intralesional rituximab salvages refractory scalp lesions in a case of pemphigus vulgaris

2019 ◽  
Vol 33 (1) ◽  
Author(s):  
Aayush Gupta ◽  
Yugal K Sharma ◽  
Jitendra S. Bhawalkar ◽  
Preeti Kothari ◽  
Rajeshri Kharat ◽  
...  
2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Marta Sar-Pomian ◽  
Lidia Rudnicka ◽  
Malgorzata Olszewska

Scalp is a unique location for pemphigus because of the abundance of desmogleins localized in hair follicles. Scalp involvement is observed in up to 60% of patients in the course of pemphigus. The lesions may occasionally lead to alopecia. Unforced removal of anagen hairs in a pull test is a sign of high disease activity. Direct immunofluorescence of plucked hair bulbs is considered a reliable diagnostic method in patients with pemphigus. Follicular acantholysis is a characteristic histopathological feature of pemphigus lesions localized on the scalp. Trichoscopy may serve as a supplementary method in the diagnosis of pemphigus. This review summarizes the most recent data concerning scalp involvement in pemphigus vulgaris and pemphigus foliaceus. A systematic literature search was conducted in three medical databases: PubMed, Embase, and Web of Science. The analysis included literature data about desmoglein distribution in hair follicles, as well as information about clinical manifestations, histopathology, immunopathology, and trichoscopy of scalp lesions in pemphigus and their response to treatment.


2014 ◽  
Vol 89 (6) ◽  
pp. 1007-1012 ◽  
Author(s):  
Marta Sar-Pomian ◽  
Marta Kurzeja ◽  
Lidia Rudnicka ◽  
Malgorzata Olszewska

2001 ◽  
Vol 144 (2) ◽  
pp. 421-422 ◽  
Author(s):  
K. Ogata ◽  
H. Nakajima ◽  
M. Ikeda ◽  
Y. Yamamoto ◽  
M. Amagai ◽  
...  

1973 ◽  
Vol 107 (5) ◽  
pp. 751-751 ◽  
Author(s):  
A. Baumal
Keyword(s):  

1969 ◽  
Vol 99 (2) ◽  
pp. 176-179 ◽  
Author(s):  
R. E. Jordon
Keyword(s):  

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